Click here to switch to the map view.

The map label for this gene is sstT

Identifier: 15602756

GI number: 15602756

Start: 1045965

End: 1047206

Strand: Reverse

Name: sstT

Synonym: PM0891

Alternate gene names: 15602756

Gene position: 1047206-1045965 (Counterclockwise)

Preceding gene: 15602758

Following gene: 15602755

Centisome position: 46.39

GC content: 40.1

Gene sequence:

>1242_bases
ATGAATACATCTCGTTTATTTAGTTTGTTTTTCCAAGGTAATTTGGTGAAACGTATTTTTATTGGTCTTATCTTAGGTTT
GCTTGTTGCGCTCGTTACGCCGACATTACAAAACGTGCTTGGTTTTAATTTAGCGGAAAAAGTTGGGGTATTAGGCACCA
TTTTTGTTCGCTCATTACGTGCTGTTGCACCGATTTTAATTTTTGTCCTTGTCATGGCGGCAATTGCAAATAAAAAAATT
GGTGCGAAAAGCAATATGAAATCCATTATTGTATTGTATCTTTTGGGGACATTTTTAGCCGCACTTTCAGCTGTTATTGC
TGGCTTCTTATTCCCAAGTGAAGTGGCATTAGCCACAAAAGAAGATATGACGTCTGCACCACAAGGTGTTGGTCAGGTAC
TATTAACTTTAGTCTTCAATGTGGTTGATAATCCATTAAATGCGCTCTTTAAAGCGAATTTCGTTGGCGTGCTCGCTTGG
TCAATTGGTTTGGGATTAGCCCTACGTCATGCATCAGAAAGTACAAAAACGATGGTGTCAGATCTAGCAGAAGCTGTATC
GAAAATTGTGTATGTGATTATTGCCTTTGCCCCAATCGGTGTGTTCGGTTTAGTCAGTGAAACCTTGGCAGATAAAGGAT
TAGTGGCGCTCGGTGGTTATATTCATTTATTAGCCGTATTAGTTGGTACGATGTTATTTGTTGCTTTTGTAGTGAACCCA
ATTTTGGTTTACTGGAAAATTCGCCGTAATCCTTATCCATTAGTGTGGACCTGCGTACGTGAAAGTGGTTTAACGGCATT
TTTCACTCGTAGCTCAGCAGCTAACATTCCAGTTAACATCAATCTTGCTAAACGCTTGAATTTAGATGAAGAAACCTATT
CGGTCTCCATTCCATTAGGCGCGACTATTAATATGGCAGGTGCTGCGATTACTGTAACGATTCTTACGTTAGCCGCGGTA
CATACTTTAGATATTCAGATTTCTTTCTTTAGTGCCTTGTTATTGAGTGTCGTTGCCAGTATTTGTGCTTGTGGTGCCTC
TGGTGTCGCGGGGGGATCTTTATTATTGATTCCGTTAGCTTGTAGCTTATTTGGGGTTTCTGATGATGTCGCTGCACAAA
TGATCGGGGTGGGGTTCATTATCGGTATTTTACAAGACTCTACTGAAACTGCATTAAACTCCTCAACGGATGTGTTGTTT
ACTGCAGCAGCCTGTATTGCAGAAGAAAATAAACAAGTTTAA

Upstream 100 bases:

>100_bases
AATGAAAAAGTAAGCTATCTTTAGCACCGTTAGGGGGATCAAACATTTGGTCTAAATTTTTTACAATAAGTGCATTCGCA
CAAGATTACGTGATTTAATT

Downstream 100 bases:

>100_bases
CGAACGGTTATTTAGTGAATAGAAAGCGGATATTTATCCGCTTTTTTTATCGGAGGATGGATGTGCAGTTTACAGCTTAA
AGAAGCCAAATTTAAATTAC

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MNTSRLFSLFFQGNLVKRIFIGLILGLLVALVTPTLQNVLGFNLAEKVGVLGTIFVRSLRAVAPILIFVLVMAAIANKKI
GAKSNMKSIIVLYLLGTFLAALSAVIAGFLFPSEVALATKEDMTSAPQGVGQVLLTLVFNVVDNPLNALFKANFVGVLAW
SIGLGLALRHASESTKTMVSDLAEAVSKIVYVIIAFAPIGVFGLVSETLADKGLVALGGYIHLLAVLVGTMLFVAFVVNP
ILVYWKIRRNPYPLVWTCVRESGLTAFFTRSSAANIPVNINLAKRLNLDEETYSVSIPLGATINMAGAAITVTILTLAAV
HTLDIQISFFSALLLSVVASICACGASGVAGGSLLLIPLACSLFGVSDDVAAQMIGVGFIIGILQDSTETALNSSTDVLF
TAAACIAEENKQV

Sequences:

>Translated_413_residues
MNTSRLFSLFFQGNLVKRIFIGLILGLLVALVTPTLQNVLGFNLAEKVGVLGTIFVRSLRAVAPILIFVLVMAAIANKKI
GAKSNMKSIIVLYLLGTFLAALSAVIAGFLFPSEVALATKEDMTSAPQGVGQVLLTLVFNVVDNPLNALFKANFVGVLAW
SIGLGLALRHASESTKTMVSDLAEAVSKIVYVIIAFAPIGVFGLVSETLADKGLVALGGYIHLLAVLVGTMLFVAFVVNP
ILVYWKIRRNPYPLVWTCVRESGLTAFFTRSSAANIPVNINLAKRLNLDEETYSVSIPLGATINMAGAAITVTILTLAAV
HTLDIQISFFSALLLSVVASICACGASGVAGGSLLLIPLACSLFGVSDDVAAQMIGVGFIIGILQDSTETALNSSTDVLF
TAAACIAEENKQV
>Mature_413_residues
MNTSRLFSLFFQGNLVKRIFIGLILGLLVALVTPTLQNVLGFNLAEKVGVLGTIFVRSLRAVAPILIFVLVMAAIANKKI
GAKSNMKSIIVLYLLGTFLAALSAVIAGFLFPSEVALATKEDMTSAPQGVGQVLLTLVFNVVDNPLNALFKANFVGVLAW
SIGLGLALRHASESTKTMVSDLAEAVSKIVYVIIAFAPIGVFGLVSETLADKGLVALGGYIHLLAVLVGTMLFVAFVVNP
ILVYWKIRRNPYPLVWTCVRESGLTAFFTRSSAANIPVNINLAKRLNLDEETYSVSIPLGATINMAGAAITVTILTLAAV
HTLDIQISFFSALLLSVVASICACGASGVAGGSLLLIPLACSLFGVSDDVAAQMIGVGFIIGILQDSTETALNSSTDVLF
TAAACIAEENKQV

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI4827012, Length=243, Percent_Identity=24.6913580246914, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI169790839, Length=243, Percent_Identity=23.8683127572016, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI223468564, Length=256, Percent_Identity=26.5625, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI223468566, Length=256, Percent_Identity=26.5625, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI5032093, Length=256, Percent_Identity=26.5625, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI66773030, Length=237, Percent_Identity=24.0506329113924, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789473, Length=414, Percent_Identity=61.3526570048309, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1789947, Length=388, Percent_Identity=23.4536082474227, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790514, Length=367, Percent_Identity=24.7956403269755, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71996953, Length=259, Percent_Identity=28.1853281853282, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193206505, Length=381, Percent_Identity=24.6719160104987, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71983099, Length=252, Percent_Identity=23.4126984126984, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71983106, Length=258, Percent_Identity=23.2558139534884, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17537407, Length=270, Percent_Identity=22.5925925925926, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583025, Length=447, Percent_Identity=23.7136465324385, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137668, Length=447, Percent_Identity=23.7136465324385, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583023, Length=447, Percent_Identity=23.7136465324385, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_PASMU (Q9CMD9)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245828.1
- ProteinModelPortal:   Q9CMD9
- SMR:   Q9CMD9
- GeneID:   1244238
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0891
- NMPDR:   fig|272843.1.peg.891
- HOGENOM:   HBG289387
- OMA:   GILQDST
- ProtClustDB:   PRK13628
- BioCyc:   PMUL272843:PM0891-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 43423; Mature: 43423

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd1caf90)-; HASH(0x403a2ef4)-; HASH(0xdb4958c)-; HASH(0xdd93f14)-; HASH(0xd34294c)-; HASH(0xd2315cc)-; HASH(0xdae6134)-; HASH(0xd513c24)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCH
>Mature Secondary Structure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HHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11248100