| Definition | Pasteurella multocida subsp. multocida str. Pm70, complete genome. |
|---|---|
| Accession | NC_002663 |
| Length | 2,257,487 |
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The map label for this gene is gyrA [H]
Identifier: 15602706
GI number: 15602706
Start: 991233
End: 993932
Strand: Direct
Name: gyrA [H]
Synonym: PM0841
Alternate gene names: 15602706
Gene position: 991233-993932 (Clockwise)
Preceding gene: 15602704
Following gene: 15602707
Centisome position: 43.91
GC content: 43.59
Gene sequence:
>2700_bases ATGATTAGGAAGTTTTCAATGACCGATTTAGTCCAAGATACTATGCATCAAGATATTAGCCCAATCAGTATTGAAGAAGA GCTGAAATCCTCATATCTCGATTATGCCATGTCCGTCATCGTAGGGCGTGCATTACCCGATGTACGCGATGGTTTGAAAC CCGTCCATCGCCGCGTATTATTTGCGATGCACGAAGGCGGGAATGCCTATAACAAACCTTATCGTAAATCCGCTCGTATC GTAGGGGATGTAATCGGTAAGTATCACCCTCATGGTGATAGCGCGGTCTATGACACACTCGTGCGCATGGCTCAGCCGTT TTCATTACGTTATATGTTAGTAGATGGGCAAGGTAACTTCGGTTCAATTGATGGCGATGCTGCCGCGGCAATGCGTTATA CTGAAGCCCGCATGACTAAAATCGCCCATGAATTATTAGCGGATCTCGATAAAGAAACTGTCAATTTTGTGCCTAACTAC GATGGCTCTGAACAAATTCCTGAAGTCCTCCCAACTAAAGTCCCTGCGCTTTTAGTCAACGGTTCTTCCGGTATTGCAGT CGGTATGGCAACTAATATTCCCCCTCATAACTTAGGCGAAGTGTTAGACGGTTGCTTAGCGTATATCGAAAACAACGAGA TCAGCATTGATGAGTTAATGACTTATATTCCAGGTCCAGACTTCCCAACCGCCGCATTAATCAATGGTCGCAAAGGGATT GAAGAAGCCTATAAAACAGGACGTGGTAAAATTTATGTACGTGCCAAAGCCGAAGTGGAAACCGATGAAAAAGGCGGTGA AACCATTGTGGTGCATGAAATTCCTTATCAAGTCAACAAAGCCAAATTAATCGAAAAAATTGCTGATCTCGTAAAAGAGA AAAAAGTCGAAGGCATTAGCGCAATCACGGATTTATCTGACAAAGACGGGATGCGTATTGAAATTAAAATCAAACGTGAT GCCGTGGGCGAAGTGGTTCTCAACAACTTGTATGCCTTGACTCAATTGCAAGTCACTTTTGGCATTAACATCGTTGCCCT CGATAAAGGTCAACCCAAACTGCTCAATTTAAAACAATTAATTGAAGCTTTCGTGTTACACCGTCGTGAAGTAGTCACAC GCCGTACCGTTTATGAATTGCGCAAAGCACGTGAGCGTGCCCATATTTTAGAAGGCTTAGCTATTGCTCTTGCCAATGTA GATCCGATTATTGAATTAATCCGCAATGCGCCAAATCCTGAAAGTGCCAAACGTGCATTATTAGCGCAAGCATGGGAGCT TGGCCATGTATCACAAATGCTTGCTGCCACAGGGGTTGATGCGGCACGTCCTGAAGATCTAGAAGAACAATACGGTATTC GTGATGGCATGTATTATCTGACCGAAGTTCAAGCACAAGCGATTTTAGATTTACGTTTACAAAAACTGACTAACTTAGGT CATGATGAAATTCTTGATGAGTACAAAAAACTCCTCGATGTGATCGGCGAATTATTACATATCTTACGTAGCCCTGAACG CTTAATGGAAGTGATTCGTGAAGAATTAGAACAAATTCGCGAACAGTTTAATGATCCACGTCGTACAGAAATTACCGCGA GCTCTGCTGATATCAATCTTGAAGACCTCATTGCCCAAGAAGATGTGGTGGTTACCCTTTCACATGAAGGTTACGTCAAA TATCAACCCCTTACTGACTACGAAGCACAACGTCGTGGTGGTAAAGGGAAATCCGCAGCCAAAACCAAAGAAGAAGATTT CATTGAGCGTCTTTTAGTCGCAAACACCCATGACACCATTCTCTGTTTCTCGAGTCGTGGACGCTTATATTGGTTAAAAG TGTATCAACTCCCACAAGCTAGCCGTGGTGCACGTGGCAGACCGATCGTCAATATTCTTCCATTAGATGAAAATGAACGT ATTACCGCGATTCTACCTGTCACTGCTTATGAAGAGGACAAATTTGTCGTGATGGCAACTGCCGGCGGTATCGTGAAAAA GATTGCCTTAACTGAATTCAGTCGTCCTCGTTCAACAGGCATTATTGCACTCAACTTGCGTGATGAAGACGAACTTATCG GTGTGGATATCACCGATGGTCAAAATGAAATCATGCTCTTCTCCGCACAAGGGCGTGTAGTTCGCTTTAGTGAAAATGCC GTGCGTGCCATGGGGCGTGCAGCAACAGGTGTACGCGGTATTAAACTGGCGTTAACGAATGATTTGTCGGATGATGAAAG TGCGGTCGATATGGAAGAGATCTCTGATGAGAATACTAATGATGCCTTGGATCTCAATATTGATAAAGTCGTGTCACTTG TTATTCCAAAAAATGAAGGCGCCATTTTAACCGCCACACAAAACGGTTATGGTAAACGTACTGAATTAGCGGAATACCCA ACTAAATCACGTAACACCAAAGGCGTGATCTCGATTAAAGTGAGTGAGCGTAACGGCAAAGTCGTTGCAGCAACACAAGT TGAGGAAAGCGATCAAATTATGCTCATTACTGATGCCGGTACGCTAGTACGTACTCGCGTAAACGAAATCAATATTATCG GTCGAAATACACAAGGAGTACGTCTCATTCGAACAAGTGAAAGTGAAACACTGGTTGGATTACAACGCGTTTGTGATGTC GATGAAGAAGACATTGAGAGTGATGCGAGCGAAAGTGCGGTCGAAAGCGCAGAAAGTTAA
Upstream 100 bases:
>100_bases ACGTTATTATTCCCCAAATCAGGCAAAATTTCACTATAAAATTAGGGGAACACTAGATTTTATGCTATAATTCCGTCAAT TTTTTGATTAATCAAACTCA
Downstream 100 bases:
>100_bases ATTCATTCACTAAATACGATATTATTTTAAAGCAGTAGCCTCGCTACTGCTTTCTTTATCTTAGGAAAAAAATCGATGGC ATATTATCTTATTTATCTAC
Product: DNA gyrase subunit A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 899; Mature: 899
Protein sequence:
>899_residues MIRKFSMTDLVQDTMHQDISPISIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHEGGNAYNKPYRKSARI VGDVIGKYHPHGDSAVYDTLVRMAQPFSLRYMLVDGQGNFGSIDGDAAAAMRYTEARMTKIAHELLADLDKETVNFVPNY DGSEQIPEVLPTKVPALLVNGSSGIAVGMATNIPPHNLGEVLDGCLAYIENNEISIDELMTYIPGPDFPTAALINGRKGI EEAYKTGRGKIYVRAKAEVETDEKGGETIVVHEIPYQVNKAKLIEKIADLVKEKKVEGISAITDLSDKDGMRIEIKIKRD AVGEVVLNNLYALTQLQVTFGINIVALDKGQPKLLNLKQLIEAFVLHRREVVTRRTVYELRKARERAHILEGLAIALANV DPIIELIRNAPNPESAKRALLAQAWELGHVSQMLAATGVDAARPEDLEEQYGIRDGMYYLTEVQAQAILDLRLQKLTNLG HDEILDEYKKLLDVIGELLHILRSPERLMEVIREELEQIREQFNDPRRTEITASSADINLEDLIAQEDVVVTLSHEGYVK YQPLTDYEAQRRGGKGKSAAKTKEEDFIERLLVANTHDTILCFSSRGRLYWLKVYQLPQASRGARGRPIVNILPLDENER ITAILPVTAYEEDKFVVMATAGGIVKKIALTEFSRPRSTGIIALNLRDEDELIGVDITDGQNEIMLFSAQGRVVRFSENA VRAMGRAATGVRGIKLALTNDLSDDESAVDMEEISDENTNDALDLNIDKVVSLVIPKNEGAILTATQNGYGKRTELAEYP TKSRNTKGVISIKVSERNGKVVAATQVEESDQIMLITDAGTLVRTRVNEINIIGRNTQGVRLIRTSESETLVGLQRVCDV DEEDIESDASESAVESAES
Sequences:
>Translated_899_residues MIRKFSMTDLVQDTMHQDISPISIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHEGGNAYNKPYRKSARI VGDVIGKYHPHGDSAVYDTLVRMAQPFSLRYMLVDGQGNFGSIDGDAAAAMRYTEARMTKIAHELLADLDKETVNFVPNY DGSEQIPEVLPTKVPALLVNGSSGIAVGMATNIPPHNLGEVLDGCLAYIENNEISIDELMTYIPGPDFPTAALINGRKGI EEAYKTGRGKIYVRAKAEVETDEKGGETIVVHEIPYQVNKAKLIEKIADLVKEKKVEGISAITDLSDKDGMRIEIKIKRD AVGEVVLNNLYALTQLQVTFGINIVALDKGQPKLLNLKQLIEAFVLHRREVVTRRTVYELRKARERAHILEGLAIALANV DPIIELIRNAPNPESAKRALLAQAWELGHVSQMLAATGVDAARPEDLEEQYGIRDGMYYLTEVQAQAILDLRLQKLTNLG HDEILDEYKKLLDVIGELLHILRSPERLMEVIREELEQIREQFNDPRRTEITASSADINLEDLIAQEDVVVTLSHEGYVK YQPLTDYEAQRRGGKGKSAAKTKEEDFIERLLVANTHDTILCFSSRGRLYWLKVYQLPQASRGARGRPIVNILPLDENER ITAILPVTAYEEDKFVVMATAGGIVKKIALTEFSRPRSTGIIALNLRDEDELIGVDITDGQNEIMLFSAQGRVVRFSENA VRAMGRAATGVRGIKLALTNDLSDDESAVDMEEISDENTNDALDLNIDKVVSLVIPKNEGAILTATQNGYGKRTELAEYP TKSRNTKGVISIKVSERNGKVVAATQVEESDQIMLITDAGTLVRTRVNEINIIGRNTQGVRLIRTSESETLVGLQRVCDV DEEDIESDASESAVESAES >Mature_899_residues MIRKFSMTDLVQDTMHQDISPISIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHEGGNAYNKPYRKSARI VGDVIGKYHPHGDSAVYDTLVRMAQPFSLRYMLVDGQGNFGSIDGDAAAAMRYTEARMTKIAHELLADLDKETVNFVPNY DGSEQIPEVLPTKVPALLVNGSSGIAVGMATNIPPHNLGEVLDGCLAYIENNEISIDELMTYIPGPDFPTAALINGRKGI EEAYKTGRGKIYVRAKAEVETDEKGGETIVVHEIPYQVNKAKLIEKIADLVKEKKVEGISAITDLSDKDGMRIEIKIKRD AVGEVVLNNLYALTQLQVTFGINIVALDKGQPKLLNLKQLIEAFVLHRREVVTRRTVYELRKARERAHILEGLAIALANV DPIIELIRNAPNPESAKRALLAQAWELGHVSQMLAATGVDAARPEDLEEQYGIRDGMYYLTEVQAQAILDLRLQKLTNLG HDEILDEYKKLLDVIGELLHILRSPERLMEVIREELEQIREQFNDPRRTEITASSADINLEDLIAQEDVVVTLSHEGYVK YQPLTDYEAQRRGGKGKSAAKTKEEDFIERLLVANTHDTILCFSSRGRLYWLKVYQLPQASRGARGRPIVNILPLDENER ITAILPVTAYEEDKFVVMATAGGIVKKIALTEFSRPRSTGIIALNLRDEDELIGVDITDGQNEIMLFSAQGRVVRFSENA VRAMGRAATGVRGIKLALTNDLSDDESAVDMEEISDENTNDALDLNIDKVVSLVIPKNEGAILTATQNGYGKRTELAEYP TKSRNTKGVISIKVSERNGKVVAATQVEESDQIMLITDAGTLVRTRVNEINIIGRNTQGVRLIRTSESETLVGLQRVCDV DEEDIESDASESAVESAES
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=169, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=2e-13, Organism=Homo sapiens, GI19913408, Length=168, Percent_Identity=31.547619047619, Blast_Score=75, Evalue=3e-13, Organism=Escherichia coli, GI1788562, Length=883, Percent_Identity=73.1596828992072, Blast_Score=1312, Evalue=0.0, Organism=Escherichia coli, GI1789396, Length=708, Percent_Identity=34.6045197740113, Blast_Score=380, Evalue=1e-106, Organism=Caenorhabditis elegans, GI212645657, Length=272, Percent_Identity=28.6764705882353, Blast_Score=78, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17535065, Length=167, Percent_Identity=32.9341317365269, Blast_Score=77, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6324241, Length=164, Percent_Identity=29.8780487804878, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI17136538, Length=180, Percent_Identity=29.4444444444444, Blast_Score=68, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 99733; Mature: 99733
Theoretical pI: Translated: 4.83; Mature: 4.83
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIRKFSMTDLVQDTMHQDISPISIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVL CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHE FAMHEGGNAYNKPYRKSARIVGDVIGKYHPHGDSAVYDTLVRMAQPFSLRYMLVDGQGNF EEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCC GSIDGDAAAAMRYTEARMTKIAHELLADLDKETVNFVPNYDGSEQIPEVLPTKVPALLVN CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHCCCCCCEEEEE GSSGIAVGMATNIPPHNLGEVLDGCLAYIENNEISIDELMTYIPGPDFPTAALINGRKGI CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHCCCCHHH EEAYKTGRGKIYVRAKAEVETDEKGGETIVVHEIPYQVNKAKLIEKIADLVKEKKVEGIS HHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHH AITDLSDKDGMRIEIKIKRDAVGEVVLNNLYALTQLQVTFGINIVALDKGQPKLLNLKQL HHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHEEEEEECEEEEEECCCCCCEECHHHH IEAFVLHRREVVTRRTVYELRKARERAHILEGLAIALANVDPIIELIRNAPNPESAKRAL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHH LAQAWELGHVSQMLAATGVDAARPEDLEEQYGIRDGMYYLTEVQAQAILDLRLQKLTNLG HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC HDEILDEYKKLLDVIGELLHILRSPERLMEVIREELEQIREQFNDPRRTEITASSADINL HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCH EDLIAQEDVVVTLSHEGYVKYQPLTDYEAQRRGGKGKSAAKTKEEDFIERLLVANTHDTI HHHHCCCCEEEEEECCCEEEECCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEE LCFSSRGRLYWLKVYQLPQASRGARGRPIVNILPLDENERITAILPVTAYEEDKFVVMAT EEEECCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEEECCCCEEEEEE AGGIVKKIALTEFSRPRSTGIIALNLRDEDELIGVDITDGQNEIMLFSAQGRVVRFSENA CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEECCCCEEEECCHH VRAMGRAATGVRGIKLALTNDLSDDESAVDMEEISDENTNDALDLNIDKVVSLVIPKNEG HHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEEEHHHEEEEEEECCCC AILTATQNGYGKRTELAEYPTKSRNTKGVISIKVSERNGKVVAATQVEESDQIMLITDAG EEEEEECCCCCCCCHHHHCCCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCEEEEECCC TLVRTRVNEINIIGRNTQGVRLIRTSESETLVGLQRVCDVDEEDIESDASESAVESAES CEEEEECCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCC >Mature Secondary Structure MIRKFSMTDLVQDTMHQDISPISIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVL CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHE FAMHEGGNAYNKPYRKSARIVGDVIGKYHPHGDSAVYDTLVRMAQPFSLRYMLVDGQGNF EEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCC GSIDGDAAAAMRYTEARMTKIAHELLADLDKETVNFVPNYDGSEQIPEVLPTKVPALLVN CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHCCCCCCEEEEE GSSGIAVGMATNIPPHNLGEVLDGCLAYIENNEISIDELMTYIPGPDFPTAALINGRKGI CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHCCCCHHH EEAYKTGRGKIYVRAKAEVETDEKGGETIVVHEIPYQVNKAKLIEKIADLVKEKKVEGIS HHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHH AITDLSDKDGMRIEIKIKRDAVGEVVLNNLYALTQLQVTFGINIVALDKGQPKLLNLKQL HHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHEEEEEECEEEEEECCCCCCEECHHHH IEAFVLHRREVVTRRTVYELRKARERAHILEGLAIALANVDPIIELIRNAPNPESAKRAL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHH LAQAWELGHVSQMLAATGVDAARPEDLEEQYGIRDGMYYLTEVQAQAILDLRLQKLTNLG HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC HDEILDEYKKLLDVIGELLHILRSPERLMEVIREELEQIREQFNDPRRTEITASSADINL HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCH EDLIAQEDVVVTLSHEGYVKYQPLTDYEAQRRGGKGKSAAKTKEEDFIERLLVANTHDTI HHHHCCCCEEEEEECCCEEEECCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEE LCFSSRGRLYWLKVYQLPQASRGARGRPIVNILPLDENERITAILPVTAYEEDKFVVMAT EEEECCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEEECCCCEEEEEE AGGIVKKIALTEFSRPRSTGIIALNLRDEDELIGVDITDGQNEIMLFSAQGRVVRFSENA CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEECCCCEEEECCHH VRAMGRAATGVRGIKLALTNDLSDDESAVDMEEISDENTNDALDLNIDKVVSLVIPKNEG HHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEEEHHHEEEEEEECCCC AILTATQNGYGKRTELAEYPTKSRNTKGVISIKVSERNGKVVAATQVEESDQIMLITDAG EEEEEECCCCCCCCHHHHCCCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCEEEEECCC TLVRTRVNEINIIGRNTQGVRLIRTSESETLVGLQRVCDVDEEDIESDASESAVESAES CEEEEECCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]