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The map label for this gene is glk [H]

Identifier: 15602657

GI number: 15602657

Start: 936596

End: 937114

Strand: Reverse

Name: glk [H]

Synonym: PM0792

Alternate gene names: 15602657

Gene position: 937114-936596 (Counterclockwise)

Preceding gene: 15602659

Following gene: 15602655

Centisome position: 41.51

GC content: 39.88

Gene sequence:

>519_bases
ATGGCAAGAGTAAAAGGCAAAGGATTCATTTTGATGGGCGTTTCCAGTACAGGAAAGACCTCGGTTGGCACGGTTGTCGC
ACAACGCTTAGGGATTAAACTCATTGATGGTGATGATCTTCATCCACGAGCCAATATCATTAAGATGGGGCAAGGGATAC
CATTAAACGATGAAGATAGAGCCCCTTGGTTAGAACGTATTCGTGATGCGGCATTTAGTTTAGAGCAGAAAAGTGAAGTT
GGGATTATTATCTGTTCAGCGTTAAAAAAACAATATCGTGATTTGATTCGTGATGGCAATGATGTGAAGTTTATTTTTTT
ACATGGTCCTTTTGAATTAGTGTTAGAACGAATGAAGCAACGTAAAGGGCATTACATGAAACCAGAAATGCTAAAAAGCC
AATTTGACACATTGGAAATTCCCCAAGCAGATGAGCCAGACGTCATTCATATCAGTATTGATGGGACGTTTGAACAAGTC
GTGGAACGTTGTATCAAGGCATTAAAACCCTTACTCTAA

Upstream 100 bases:

>100_bases
ACTAAAAAATGTGATATTTATCACAAAAGGTGATGTTACCAGTAACGTTTTGTTGGGATTTTAGGTATGGTAAGCAAAAA
AGCGTAAAGAGGAGTTCGTT

Downstream 100 bases:

>100_bases
TTAAAAGCCTGTTCTGTTAACCGCACTTTTGTCCTCGTGAGGAAAGTGCGGTCGTTTTTTTAGATACTTTCACCGAGATG
AATTTGGTAGCCTAAATTGA

Product: Glk

Products: NA

Alternate protein names: Gluconate kinase 1 [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MARVKGKGFILMGVSSTGKTSVGTVVAQRLGIKLIDGDDLHPRANIIKMGQGIPLNDEDRAPWLERIRDAAFSLEQKSEV
GIIICSALKKQYRDLIRDGNDVKFIFLHGPFELVLERMKQRKGHYMKPEMLKSQFDTLEIPQADEPDVIHISIDGTFEQV
VERCIKALKPLL

Sequences:

>Translated_172_residues
MARVKGKGFILMGVSSTGKTSVGTVVAQRLGIKLIDGDDLHPRANIIKMGQGIPLNDEDRAPWLERIRDAAFSLEQKSEV
GIIICSALKKQYRDLIRDGNDVKFIFLHGPFELVLERMKQRKGHYMKPEMLKSQFDTLEIPQADEPDVIHISIDGTFEQV
VERCIKALKPLL
>Mature_171_residues
ARVKGKGFILMGVSSTGKTSVGTVVAQRLGIKLIDGDDLHPRANIIKMGQGIPLNDEDRAPWLERIRDAAFSLEQKSEVG
IIICSALKKQYRDLIRDGNDVKFIFLHGPFELVLERMKQRKGHYMKPEMLKSQFDTLEIPQADEPDVIHISIDGTFEQVV
ERCIKALKPLL

Specific function: Gluconate utilization system GNT-II. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=181, Percent_Identity=39.2265193370166, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI1790719, Length=166, Percent_Identity=55.421686746988, Blast_Score=196, Evalue=8e-52,
Organism=Escherichia coli, GI87082265, Length=162, Percent_Identity=50.6172839506173, Blast_Score=179, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI25146487, Length=165, Percent_Identity=35.1515151515151, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320454, Length=177, Percent_Identity=40.6779661016949, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 19383; Mature: 19252

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVKGKGFILMGVSSTGKTSVGTVVAQRLGIKLIDGDDLHPRANIIKMGQGIPLNDEDR
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCEEEECCCCCCCCCCEEECCCCCCCCCCCC
APWLERIRDAAFSLEQKSEVGIIICSALKKQYRDLIRDGNDVKFIFLHGPFELVLERMKQ
CHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHH
RKGHYMKPEMLKSQFDTLEIPQADEPDVIHISIDGTFEQVVERCIKALKPLL
HCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARVKGKGFILMGVSSTGKTSVGTVVAQRLGIKLIDGDDLHPRANIIKMGQGIPLNDEDR
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCEEEECCCCCCCCCCEEECCCCCCCCCCCC
APWLERIRDAAFSLEQKSEVGIIICSALKKQYRDLIRDGNDVKFIFLHGPFELVLERMKQ
CHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHH
RKGHYMKPEMLKSQFDTLEIPQADEPDVIHISIDGTFEQVVERCIKALKPLL
HCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]