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The map label for this gene is dapD

Identifier: 15602523

GI number: 15602523

Start: 760786

End: 761610

Strand: Reverse

Name: dapD

Synonym: PM0658

Alternate gene names: 15602523

Gene position: 761610-760786 (Counterclockwise)

Preceding gene: 15602525

Following gene: 15602522

Centisome position: 33.74

GC content: 41.94

Gene sequence:

>825_bases
ATGTCATTACAACATATCATTGAAGCCGCTTTTGAAAAGCGCGCAGAAATCACCCCAAAAACAGTCGATGCGCAAACGCG
AGCCGCGATTGAAGAAGCGATTGAAGGCTTAGATTCGGGAAAATATCGCGTAGCAGAAAAAATTGATGGAGAATGGGTCA
CACATCAATGGTTAAAAAAAGCAGTGTTATTGTCTTTCCGTATTAATGATAATGAGTTAGTCGCCGGCAGTGAGACAAAT
TACTATGATAAAGTGCCAATGAAATTTGCTGAATATGATGCGGCACGTTTTCAACAAGAAGGTTTCCGTGTTGTGCCTCC
TGCAGCTGTGCGTAAAGGCGCCTATATCGCTAAAAATACGGTTTTAATGCCATCTTATGTCAATATTGGTGCCCGTGTTG
ATGAAGGTACTATGGTGGATACTTGGGCAACGGTTGGTTCTTGTGCGCAAATTGGTAAAAATGTGCATTTATCAGGCGGT
GTTGGCATTGGTGGGGTATTAGAACCATTGCAAGCCAATCCAACGATTATTGAAGATAACTGTTTTATTGGTGCACGCTC
TGAAATTGTCGAAGGGGTGATTGTGGAAGAAGGGTCTGTCATCTCTATGGGCGTTTTCATTGGACAATCAACCAAAATTT
ACGATCGTGAAACGGGCGAAGTAACTTATGGTCGAGTTCCTGCGGGGTCTGTGGTGGTTTCGGGTAGCCTTCCATCTAAA
TGTGGCAAATATAGTTTATATTGCGCTGTAATCGTGAAAAAAGTCGATGCTAAAACCTTAGGTAAAGTCGGTATTAACGA
ATTATTACGAACAATTGATGAATAG

Upstream 100 bases:

>100_bases
AATCTCAATTCAGGCTGACCTTTTAAATTAAAAGGTGAGTTTTTATCTGAAATATGATAAAACTAAGGGCTTTAAACGTT
CATCCATTGAGGAAAATTGC

Downstream 100 bases:

>100_bases
TGTTGTTAGCTCACTTTCTTTTTAAAATTTGATTAAAACTGACCGCACTTTGTTTCTTTCAAGATAAAGTGCGGTCAGTT
TTTTATTAATTTATCCATGA

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSLQHIIEAAFEKRAEITPKTVDAQTRAAIEEAIEGLDSGKYRVAEKIDGEWVTHQWLKKAVLLSFRINDNELVAGSETN
YYDKVPMKFAEYDAARFQQEGFRVVPPAAVRKGAYIAKNTVLMPSYVNIGARVDEGTMVDTWATVGSCAQIGKNVHLSGG
VGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIYDRETGEVTYGRVPAGSVVVSGSLPSK
CGKYSLYCAVIVKKVDAKTLGKVGINELLRTIDE

Sequences:

>Translated_274_residues
MSLQHIIEAAFEKRAEITPKTVDAQTRAAIEEAIEGLDSGKYRVAEKIDGEWVTHQWLKKAVLLSFRINDNELVAGSETN
YYDKVPMKFAEYDAARFQQEGFRVVPPAAVRKGAYIAKNTVLMPSYVNIGARVDEGTMVDTWATVGSCAQIGKNVHLSGG
VGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIYDRETGEVTYGRVPAGSVVVSGSLPSK
CGKYSLYCAVIVKKVDAKTLGKVGINELLRTIDE
>Mature_273_residues
SLQHIIEAAFEKRAEITPKTVDAQTRAAIEEAIEGLDSGKYRVAEKIDGEWVTHQWLKKAVLLSFRINDNELVAGSETNY
YDKVPMKFAEYDAARFQQEGFRVVPPAAVRKGAYIAKNTVLMPSYVNIGARVDEGTMVDTWATVGSCAQIGKNVHLSGGV
GIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIYDRETGEVTYGRVPAGSVVVSGSLPSKC
GKYSLYCAVIVKKVDAKTLGKVGINELLRTIDE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=84.8708487084871, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_PASMU (Q9CMZ2)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245595.1
- ProteinModelPortal:   Q9CMZ2
- SMR:   Q9CMZ2
- GeneID:   1244005
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0658
- NMPDR:   fig|272843.1.peg.658
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- ProtClustDB:   PRK11830
- BioCyc:   PMUL272843:PM0658-MONOMER
- BRENDA:   2.3.1.117
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29664; Mature: 29533

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 103-103 BINDING 140-140

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQHIIEAAFEKRAEITPKTVDAQTRAAIEEAIEGLDSGKYRVAEKIDGEWVTHQWLKK
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHCCCCHHHHHHHHH
AVLLSFRINDNELVAGSETNYYDKVPMKFAEYDAARFQQEGFRVVPPAAVRKGAYIAKNT
HEEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEECCHHHHHCCCEEECCE
VLMPSYVNIGARVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDN
EECCCHHCCCCEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCCEEECC
CFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIYDRETGEVTYGRVPAGSVVVSGSLPSK
CEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEEECCCCCC
CGKYSLYCAVIVKKVDAKTLGKVGINELLRTIDE
CCCCEEEHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLQHIIEAAFEKRAEITPKTVDAQTRAAIEEAIEGLDSGKYRVAEKIDGEWVTHQWLKK
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHCCCCHHHHHHHHH
AVLLSFRINDNELVAGSETNYYDKVPMKFAEYDAARFQQEGFRVVPPAAVRKGAYIAKNT
HEEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEECCHHHHHCCCEEECCE
VLMPSYVNIGARVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDN
EECCCHHCCCCEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCCEEECC
CFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIYDRETGEVTYGRVPAGSVVVSGSLPSK
CEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEEECCCCCC
CGKYSLYCAVIVKKVDAKTLGKVGINELLRTIDE
CCCCEEEHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100