Click here to switch to the map view.

The map label for this gene is ihfA

Identifier: 15602493

GI number: 15602493

Start: 730350

End: 730646

Strand: Reverse

Name: ihfA

Synonym: PM0628

Alternate gene names: 15602493

Gene position: 730646-730350 (Counterclockwise)

Preceding gene: 15602494

Following gene: 15602492

Centisome position: 32.37

GC content: 38.72

Gene sequence:

>297_bases
ATGACACTGACCAAAGTAGAACTCGCAGACAATTTAATTGAAAAACTTCATTTAAATAAACGTGATGCGAAAGAATTAGT
GGAAAACTTTTTTGAAGAAATTCGAGTTGCATTAGAAACAGGCGAAGATGTCAAACTTTCTGGCTTTGGTAATTTTGAAT
TACGGGATAAATCATCTCGCCCAGGTCGAAATCCTAAAACGGGTGAAAGTGTTCCTGTTTCTGCTCGTCGTGTCGTGGCA
TTCAAACCTGGTCAAAAACTTCGTGCCCGCGTAGAAAAAACGAAACCAAAGAGTTAA

Upstream 100 bases:

>100_bases
TAATGAAAAAACTCTTGAGGAAGATGATATCAACGCAGTGGTTTCTGTTGTATTGTCTGAGTTAAAACAACGTTTTAATG
CTTATTTGAGAGATTAAATT

Downstream 100 bases:

>100_bases
TTTTCGCTTTTGAAGTACGCTTTCAAATCGTTAAGCTATCTGTAGGCTAACTATGGATAGCTTTCCTTTTGGTAGAAAAA
ATATGAAGATGTTATTAAAG

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MTLTKVELADNLIEKLHLNKRDAKELVENFFEEIRVALETGEDVKLSGFGNFELRDKSSRPGRNPKTGESVPVSARRVVA
FKPGQKLRARVEKTKPKS

Sequences:

>Translated_98_residues
MTLTKVELADNLIEKLHLNKRDAKELVENFFEEIRVALETGEDVKLSGFGNFELRDKSSRPGRNPKTGESVPVSARRVVA
FKPGQKLRARVEKTKPKS
>Mature_97_residues
TLTKVELADNLIEKLHLNKRDAKELVENFFEEIRVALETGEDVKLSGFGNFELRDKSSRPGRNPKTGESVPVSARRVVAF
KPGQKLRARVEKTKPKS

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=97, Percent_Identity=71.1340206185567, Blast_Score=144, Evalue=7e-37,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=37.0786516853933, Blast_Score=66, Evalue=4e-13,
Organism=Escherichia coli, GI1787141, Length=90, Percent_Identity=36.6666666666667, Blast_Score=66, Evalue=5e-13,
Organism=Escherichia coli, GI1786644, Length=86, Percent_Identity=30.2325581395349, Blast_Score=62, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_PASMU (Q9CN18)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245565.1
- ProteinModelPortal:   Q9CN18
- SMR:   Q9CN18
- GeneID:   1243975
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0628
- NMPDR:   fig|272843.1.peg.628
- HOGENOM:   HBG705085
- OMA:   RPKVTKS
- ProtClustDB:   PRK00285
- BioCyc:   PMUL272843:PM0628-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 11078; Mature: 10947

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTKVELADNLIEKLHLNKRDAKELVENFFEEIRVALETGEDVKLSGFGNFELRDKSSR
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCCCC
PGRNPKTGESVPVSARRVVAFKPGQKLRARVEKTKPKS
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLTKVELADNLIEKLHLNKRDAKELVENFFEEIRVALETGEDVKLSGFGNFELRDKSSR
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCCCC
PGRNPKTGESVPVSARRVVAFKPGQKLRARVEKTKPKS
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100