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The map label for this gene is aspC [H]

Identifier: 15602486

GI number: 15602486

Start: 724950

End: 726140

Strand: Direct

Name: aspC [H]

Synonym: PM0621

Alternate gene names: 15602486

Gene position: 724950-726140 (Clockwise)

Preceding gene: 15602485

Following gene: 15602491

Centisome position: 32.11

GC content: 39.88

Gene sequence:

>1191_bases
ATGTTTGAAAATATTACCGCCGCGCCAGCTGATCCGATTTTAGGTTTAGGGGAATCATTTAAAGCGGAAACGCGCGATAA
TAAAATCAATCTTGGCATTGGTGTATATAAAGATGCGAAAGGCAATACACCAATTATGCGTGCGGTCAAAGAGGCAGAAA
AGCGCTTATTTGATCTTGAAATGAGCAAAAATTATTTAGCTATTGACGGGGTCGCAGAATTCAATGCCTGTACGAAAGAA
TTGTTATTTGGCGCAGATTCAGAGATAGTTAAACAAGGTCGTGCAAAAACCGTTCAAAGTTTAGGTGGTACTGGTGCATT
ACGTATCGCAGCAGAGTTTATTAAACGCCAAACTAAATCACAAAATGTTTGGATTAGCACACCAACTTGGCCAAACCATA
ATGCGATTTTTAATGCTGTCGGCATGACGATTCGTGAATACCGCTATTATGATGCAGAAAATAAATGCTTAGATTGGGAT
AACTTAATTGCTGATTTAAGCAATGCGGGGGAAGGCGATGTTGTTTTACTACATGGTTGCTGTCATAACCCGACTGGAAT
TGACCCTACTCCAGCACAATGGCAACAATTAGCCAAGATGTCGGAAGAAAAAGGTTGGTTACCGTTATTTGACTTTGCTT
ACCAAGGTTTTGCAAATGGTCTCGAAGAAGATGCGTTTGGTTTACGTACCTTTGCCAAAAATCATAAAGAATTATTAGTC
GCAAGTTCTTATTCTAAAAACTTTGGTCTTTATAGCGAGCGCGTTGGTGCTTTCACGTTAGTGGCAGAAACAGAGCAAAT
AGCCGCGACGGCACTCACGCAAGTCAAAACCATTATTCGTACGCTCTATTCTAACCCAGCATCACATGGCGCAACGACAG
TTTCTATGGTATTAAAAGACAGTCAGTTACGTGCCGAGTGGGAAAACGAATTAACCGAAATGCGTGAACGTATTAAGCAA
ATGCGTAGCCAATTTGTTGAATTATTGAAAGCATTTGCTTCAGAACAAGATTTTAGTTTTATTATTGATCAAAATGGGAT
GTTCTCTTTCTGTGGCTTAAATCCAGCACAAATGGATCGTTTAAAAGAGGAATTTGCCATTTATGCCGTGCGTTCTGGTC
GGATTAATGTCGCAGGCATTACTGAACAGAATATTCGTTATCTGTGTGAAAGTATTGCGAAAGTCCTTTAA

Upstream 100 bases:

>100_bases
GGATGAGTTTTTAAATTCCTTTAAAGCGGGCTTGATAATATTTGCCTCGTGCAGTATAACTAGCTCACCGATAACTAAAC
ACAACATTAAGGATTTCATT

Downstream 100 bases:

>100_bases
TTATATTTTCATAACAAAGAAAAAACCGCACTATAAAAAGTGCGGTTCTTTTTTTCTTTTTTTACCAGCGTGCTAAGGCT
TGCTGATCAGTATCGCGACT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MFENITAAPADPILGLGESFKAETRDNKINLGIGVYKDAKGNTPIMRAVKEAEKRLFDLEMSKNYLAIDGVAEFNACTKE
LLFGADSEIVKQGRAKTVQSLGGTGALRIAAEFIKRQTKSQNVWISTPTWPNHNAIFNAVGMTIREYRYYDAENKCLDWD
NLIADLSNAGEGDVVLLHGCCHNPTGIDPTPAQWQQLAKMSEEKGWLPLFDFAYQGFANGLEEDAFGLRTFAKNHKELLV
ASSYSKNFGLYSERVGAFTLVAETEQIAATALTQVKTIIRTLYSNPASHGATTVSMVLKDSQLRAEWENELTEMRERIKQ
MRSQFVELLKAFASEQDFSFIIDQNGMFSFCGLNPAQMDRLKEEFAIYAVRSGRINVAGITEQNIRYLCESIAKVL

Sequences:

>Translated_396_residues
MFENITAAPADPILGLGESFKAETRDNKINLGIGVYKDAKGNTPIMRAVKEAEKRLFDLEMSKNYLAIDGVAEFNACTKE
LLFGADSEIVKQGRAKTVQSLGGTGALRIAAEFIKRQTKSQNVWISTPTWPNHNAIFNAVGMTIREYRYYDAENKCLDWD
NLIADLSNAGEGDVVLLHGCCHNPTGIDPTPAQWQQLAKMSEEKGWLPLFDFAYQGFANGLEEDAFGLRTFAKNHKELLV
ASSYSKNFGLYSERVGAFTLVAETEQIAATALTQVKTIIRTLYSNPASHGATTVSMVLKDSQLRAEWENELTEMRERIKQ
MRSQFVELLKAFASEQDFSFIIDQNGMFSFCGLNPAQMDRLKEEFAIYAVRSGRINVAGITEQNIRYLCESIAKVL
>Mature_396_residues
MFENITAAPADPILGLGESFKAETRDNKINLGIGVYKDAKGNTPIMRAVKEAEKRLFDLEMSKNYLAIDGVAEFNACTKE
LLFGADSEIVKQGRAKTVQSLGGTGALRIAAEFIKRQTKSQNVWISTPTWPNHNAIFNAVGMTIREYRYYDAENKCLDWD
NLIADLSNAGEGDVVLLHGCCHNPTGIDPTPAQWQQLAKMSEEKGWLPLFDFAYQGFANGLEEDAFGLRTFAKNHKELLV
ASSYSKNFGLYSERVGAFTLVAETEQIAATALTQVKTIIRTLYSNPASHGATTVSMVLKDSQLRAEWENELTEMRERIKQ
MRSQFVELLKAFASEQDFSFIIDQNGMFSFCGLNPAQMDRLKEEFAIYAVRSGRINVAGITEQNIRYLCESIAKVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=42.9292929292929, Blast_Score=351, Evalue=8e-97,
Organism=Homo sapiens, GI4504067, Length=397, Percent_Identity=43.5768261964735, Blast_Score=336, Evalue=3e-92,
Organism=Homo sapiens, GI117414139, Length=380, Percent_Identity=28.6842105263158, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=61.6161616161616, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=41.5617128463476, Blast_Score=342, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=43.5443037974684, Blast_Score=369, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=40, Blast_Score=345, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17569539, Length=394, Percent_Identity=37.5634517766497, Blast_Score=293, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17569537, Length=394, Percent_Identity=31.2182741116751, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI25147136, Length=220, Percent_Identity=37.2727272727273, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=34.2205323193916, Blast_Score=177, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=36.5432098765432, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6322743, Length=429, Percent_Identity=32.4009324009324, Blast_Score=234, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=41.1616161616162, Blast_Score=335, Evalue=3e-92,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=41.1616161616162, Blast_Score=335, Evalue=3e-92,
Organism=Drosophila melanogaster, GI19920542, Length=390, Percent_Identity=41.5384615384615, Blast_Score=333, Evalue=1e-91,
Organism=Drosophila melanogaster, GI19922362, Length=395, Percent_Identity=38.9873417721519, Blast_Score=318, Evalue=5e-87,
Organism=Drosophila melanogaster, GI24654046, Length=395, Percent_Identity=38.9873417721519, Blast_Score=318, Evalue=5e-87,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44196; Mature: 44196

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENITAAPADPILGLGESFKAETRDNKINLGIGVYKDAKGNTPIMRAVKEAEKRLFDLE
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
MSKNYLAIDGVAEFNACTKELLFGADSEIVKQGRAKTVQSLGGTGALRIAAEFIKRQTKS
CCCCEEEECCCHHHHHHHHHHHCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCC
QNVWISTPTWPNHNAIFNAVGMTIREYRYYDAENKCLDWDNLIADLSNAGEGDVVLLHGC
CCEEEECCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCCCCCEEEEECC
CHNPTGIDPTPAQWQQLAKMSEEKGWLPLFDFAYQGFANGLEEDAFGLRTFAKNHKELLV
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHEEE
ASSYSKNFGLYSERVGAFTLVAETEQIAATALTQVKTIIRTLYSNPASHGATTVSMVLKD
ECCCCCCCCCHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SQLRAEWENELTEMRERIKQMRSQFVELLKAFASEQDFSFIIDQNGMFSFCGLNPAQMDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCHHHHHH
LKEEFAIYAVRSGRINVAGITEQNIRYLCESIAKVL
HHHHHHEEEEECCEEEEEECCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFENITAAPADPILGLGESFKAETRDNKINLGIGVYKDAKGNTPIMRAVKEAEKRLFDLE
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
MSKNYLAIDGVAEFNACTKELLFGADSEIVKQGRAKTVQSLGGTGALRIAAEFIKRQTKS
CCCCEEEECCCHHHHHHHHHHHCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCC
QNVWISTPTWPNHNAIFNAVGMTIREYRYYDAENKCLDWDNLIADLSNAGEGDVVLLHGC
CCEEEECCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCCCCCEEEEECC
CHNPTGIDPTPAQWQQLAKMSEEKGWLPLFDFAYQGFANGLEEDAFGLRTFAKNHKELLV
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHEEE
ASSYSKNFGLYSERVGAFTLVAETEQIAATALTQVKTIIRTLYSNPASHGATTVSMVLKD
ECCCCCCCCCHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SQLRAEWENELTEMRERIKQMRSQFVELLKAFASEQDFSFIIDQNGMFSFCGLNPAQMDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCHHHHHH
LKEEFAIYAVRSGRINVAGITEQNIRYLCESIAKVL
HHHHHHEEEEECCEEEEEECCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]