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The map label for this gene is grx2 [H]

Identifier: 15602383

GI number: 15602383

Start: 595680

End: 596327

Strand: Direct

Name: grx2 [H]

Synonym: PM0518

Alternate gene names: 15602383

Gene position: 595680-596327 (Clockwise)

Preceding gene: 15602382

Following gene: 15602384

Centisome position: 26.39

GC content: 37.5

Gene sequence:

>648_bases
ATGGAACTCTATGTTTATGATCATTGCCCTTATTGTGTCCGTGCGATGATGATTTTTGGCTTAAAGAACATACCCTTCAA
AAAACATGTTCTGTTAAATGATGATGAAGAAACCCCAATTCGTTTAGTGGGAAAAAAAGTGGTGCCTATTTTAGTGAAAG
AAGACGGTACTGCCATGCCAGAAAGCTTAGATATTGTGAAATACATTGACGCACATTATGGAGAAGCGATTTTACAGACA
GCGGTTCGTCCAGAAATTGAGGCATTGTTAGCGGAAATCACGAGTTATTCTAATTATTTATTGATGCCACGTTTCGTAAA
ACTGGACTTGGCGGAATTTGCTACGCAAAGTGCGATTGATTATTTCACCAAAAAGAAAACCGACTATGTGGGTGATTTTA
CGCAACATTTCAATAATACGCCGACTTATCTTGCACGTTTAACACAAGATCTTGAAAAATTATCTGCGCTCGTAATGGGG
GAAACTTCATTAAATCAGCATTTGTCATTCGAAGATATTTTAGTTTTTCCGTTGCTGAGAAACTTAACTTGTGTCAAAGG
ACTTCGTTTTCCTGCGCGCTTAGAAAAGTATATCAAACGTTTGTCCGAATTGAGTAAAGTTGAACTTTACACCTCACAGG
CAATTTAA

Upstream 100 bases:

>100_bases
CCAGTAAAAAGACAAAGTGGCTTGAACCAATTGTTAGTTGAATTATTTAACAAATCTGATTAGAGTAAACTATTTCATGT
AAATTAAAAGGAGTAAAAAA

Downstream 100 bases:

>100_bases
TTGGTTAAAAAGGTTGCAATTTTCGCCAAAAATTTTATTCTTGTTGATGAGAATTTCGTCTCATGGGAACTTTATAAGAA
GGAGAACAATATGGCATTAG

Product: glutaredoxin 2

Products: NA

Alternate protein names: Grx2 [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MELYVYDHCPYCVRAMMIFGLKNIPFKKHVLLNDDEETPIRLVGKKVVPILVKEDGTAMPESLDIVKYIDAHYGEAILQT
AVRPEIEALLAEITSYSNYLLMPRFVKLDLAEFATQSAIDYFTKKKTDYVGDFTQHFNNTPTYLARLTQDLEKLSALVMG
ETSLNQHLSFEDILVFPLLRNLTCVKGLRFPARLEKYIKRLSELSKVELYTSQAI

Sequences:

>Translated_215_residues
MELYVYDHCPYCVRAMMIFGLKNIPFKKHVLLNDDEETPIRLVGKKVVPILVKEDGTAMPESLDIVKYIDAHYGEAILQT
AVRPEIEALLAEITSYSNYLLMPRFVKLDLAEFATQSAIDYFTKKKTDYVGDFTQHFNNTPTYLARLTQDLEKLSALVMG
ETSLNQHLSFEDILVFPLLRNLTCVKGLRFPARLEKYIKRLSELSKVELYTSQAI
>Mature_215_residues
MELYVYDHCPYCVRAMMIFGLKNIPFKKHVLLNDDEETPIRLVGKKVVPILVKEDGTAMPESLDIVKYIDAHYGEAILQT
AVRPEIEALLAEITSYSNYLLMPRFVKLDLAEFATQSAIDYFTKKKTDYVGDFTQHFNNTPTYLARLTQDLEKLSALVMG
ETSLNQHLSFEDILVFPLLRNLTCVKGLRFPARLEKYIKRLSELSKVELYTSQAI

Specific function: Involved in reducing some disulfides in a coupled system with glutathione reductase. Does not act as hydrogen donor for ribonucleotide reductase [H]

COG id: COG2999

COG function: function code O; Glutaredoxin 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787303, Length=215, Percent_Identity=46.046511627907, Blast_Score=208, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR007494
- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR011901
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF04399 Glutaredoxin2_C [H]

EC number: NA

Molecular weight: Translated: 24706; Mature: 24706

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELYVYDHCPYCVRAMMIFGLKNIPFKKHVLLNDDEETPIRLVGKKVVPILVKEDGTAMP
CEEEEECCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHCCCCEEEEECCCCCCCC
ESLDIVKYIDAHYGEAILQTAVRPEIEALLAEITSYSNYLLMPRFVKLDLAEFATQSAID
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHH
YFTKKKTDYVGDFTQHFNNTPTYLARLTQDLEKLSALVMGETSLNQHLSFEDILVFPLLR
HHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHH
NLTCVKGLRFPARLEKYIKRLSELSKVELYTSQAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELYVYDHCPYCVRAMMIFGLKNIPFKKHVLLNDDEETPIRLVGKKVVPILVKEDGTAMP
CEEEEECCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHCCCCEEEEECCCCCCCC
ESLDIVKYIDAHYGEAILQTAVRPEIEALLAEITSYSNYLLMPRFVKLDLAEFATQSAID
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHH
YFTKKKTDYVGDFTQHFNNTPTYLARLTQDLEKLSALVMGETSLNQHLSFEDILVFPLLR
HHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHH
NLTCVKGLRFPARLEKYIKRLSELSKVELYTSQAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]