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The map label for this gene is lst

Identifier: 15602373

GI number: 15602373

Start: 582376

End: 583302

Strand: Direct

Name: lst

Synonym: PM0508

Alternate gene names: 15602373

Gene position: 582376-583302 (Clockwise)

Preceding gene: 15602372

Following gene: 15602374

Centisome position: 25.8

GC content: 35.06

Gene sequence:

>927_bases
ATGAATTTGATTATTTGTTGTACACCGTTACAGGTGTTGATTGCAGAAAAAATTATCGCTAAATTTCCGCATATGCCATT
TTATGGCGTCATGCTTTCAACAGTCAGTAATAAAAAATTTGATTTTTATGCAAAGCGGCTTGCGCAACAGTGCCAAGGTT
TTTTTTCCATGGTGCAGCATAAGGATCGCTTCAATCTATTAAAAGAAATTCTGTATTTAAAACGAACATTTTCGGGTAAG
CACTTTGATCAGGTTTTTGTGGCAAACATTAATGACTTACAAATTCAGTTTTTATTAAGTGCCATCGACTTTAATCTGTT
AAATACCTTTGATGACGGCACAATTAATATTGTACCGAATAGTCTTTTTTACCAAGATGACCCTGCCACGTTGCAGCGAA
AACTGATTAATGTGCTGTTAGGTAATAAATACAGTATTCAATCATTACGCGCTTTATCCCATACACACTACACTATTTAT
AAAGGCTTCAAGAATATTATTGAACGGGTAGAGCCGATTGAATTGGTCGCAGCAGATAACAGTGAAAAAGTCACTTCAGC
GGTGATTAACGTATTGCTTGGGCAACCCGTTTTTGCTGAAGATGAACGCAATATTGCCTTAGCGGAACGCGTGATCAAAC
AATTTAATATTCATTATTATTTGCCTCATCCACGCGAAAAGTATCGTTTAGCCCAAGTCAATTACATTGATACGGAATTG
ATCTTTGAAGATTATATTCTTCAGCAATGTCAAACCCACAAATACTGTGTTTATACATATTTTAGTAGCGCCATTATTAA
TATCATGAATAAAAGTGACAATATTGAAGTGGTAGCATTAAAAATTGACACAGAAAATCCCGCCTATGATGCTTGTTATG
ATTTGTTTGATGAGCTAGGCGTTAACGTTATTGATATAAGAGAGTAA

Upstream 100 bases:

>100_bases
ACCCTCACGGAGATCCAGTTTGTGCCATTAGCCAGTATTATTGGTGCAGTCAGCATTTTACCGGTGTTGTATTGGATGAC
GGCTAAAGTAGGAAAGTAAA

Downstream 100 bases:

>100_bases
TATGCAGAAATGGCTTATTTCATTAGAAAAAGATCACGCGCGTCGTGAGCATTTTTTTGCTCAACCAGATACGGCGGACT
TCACTGTCTTTTCTGCAATG

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha 2,3-ST; Beta-galactoside alpha-2,3-sialyltransferase; Lipooligosaccharide sialyltransferase

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNLIICCTPLQVLIAEKIIAKFPHMPFYGVMLSTVSNKKFDFYAKRLAQQCQGFFSMVQHKDRFNLLKEILYLKRTFSGK
HFDQVFVANINDLQIQFLLSAIDFNLLNTFDDGTINIVPNSLFYQDDPATLQRKLINVLLGNKYSIQSLRALSHTHYTIY
KGFKNIIERVEPIELVAADNSEKVTSAVINVLLGQPVFAEDERNIALAERVIKQFNIHYYLPHPREKYRLAQVNYIDTEL
IFEDYILQQCQTHKYCVYTYFSSAIINIMNKSDNIEVVALKIDTENPAYDACYDLFDELGVNVIDIRE

Sequences:

>Translated_308_residues
MNLIICCTPLQVLIAEKIIAKFPHMPFYGVMLSTVSNKKFDFYAKRLAQQCQGFFSMVQHKDRFNLLKEILYLKRTFSGK
HFDQVFVANINDLQIQFLLSAIDFNLLNTFDDGTINIVPNSLFYQDDPATLQRKLINVLLGNKYSIQSLRALSHTHYTIY
KGFKNIIERVEPIELVAADNSEKVTSAVINVLLGQPVFAEDERNIALAERVIKQFNIHYYLPHPREKYRLAQVNYIDTEL
IFEDYILQQCQTHKYCVYTYFSSAIINIMNKSDNIEVVALKIDTENPAYDACYDLFDELGVNVIDIRE
>Mature_308_residues
MNLIICCTPLQVLIAEKIIAKFPHMPFYGVMLSTVSNKKFDFYAKRLAQQCQGFFSMVQHKDRFNLLKEILYLKRTFSGK
HFDQVFVANINDLQIQFLLSAIDFNLLNTFDDGTINIVPNSLFYQDDPATLQRKLINVLLGNKYSIQSLRALSHTHYTIY
KGFKNIIERVEPIELVAADNSEKVTSAVINVLLGQPVFAEDERNIALAERVIKQFNIHYYLPHPREKYRLAQVNYIDTEL
IFEDYILQQCQTHKYCVYTYFSSAIINIMNKSDNIEVVALKIDTENPAYDACYDLFDELGVNVIDIRE

Specific function: Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 52 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LST_PASMU (Q9CNC4)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245445.1
- GeneID:   1243855
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0508
- NMPDR:   fig|272843.1.peg.508
- HOGENOM:   HBG495263
- OMA:   ERIMAQH
- ProtClustDB:   CLSK870133
- BioCyc:   PMUL272843:PM0508-MONOMER
- InterPro:   IPR012477

Pfam domain/function: PF07922 Glyco_transf_52

EC number: NA

Molecular weight: Translated: 35725; Mature: 35725

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIICCTPLQVLIAEKIIAKFPHMPFYGVMLSTVSNKKFDFYAKRLAQQCQGFFSMVQH
CCEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
KDRFNLLKEILYLKRTFSGKHFDQVFVANINDLQIQFLLSAIDFNLLNTFDDGTINIVPN
CHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
SLFYQDDPATLQRKLINVLLGNKYSIQSLRALSHTHYTIYKGFKNIIERVEPIELVAADN
CEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
SEKVTSAVINVLLGQPVFAEDERNIALAERVIKQFNIHYYLPHPREKYRLAQVNYIDTEL
CHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCHHHHEEEEEEECHHHH
IFEDYILQQCQTHKYCVYTYFSSAIINIMNKSDNIEVVALKIDTENPAYDACYDLFDELG
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHC
VNVIDIRE
CCEEEECC
>Mature Secondary Structure
MNLIICCTPLQVLIAEKIIAKFPHMPFYGVMLSTVSNKKFDFYAKRLAQQCQGFFSMVQH
CCEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
KDRFNLLKEILYLKRTFSGKHFDQVFVANINDLQIQFLLSAIDFNLLNTFDDGTINIVPN
CHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
SLFYQDDPATLQRKLINVLLGNKYSIQSLRALSHTHYTIYKGFKNIIERVEPIELVAADN
CEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
SEKVTSAVINVLLGQPVFAEDERNIALAERVIKQFNIHYYLPHPREKYRLAQVNYIDTEL
CHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCHHHHEEEEEEECHHHH
IFEDYILQQCQTHKYCVYTYFSSAIINIMNKSDNIEVVALKIDTENPAYDACYDLFDELG
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHC
VNVIDIRE
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100