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The map label for this gene is erpA

Identifier: 15602323

GI number: 15602323

Start: 533136

End: 533480

Strand: Reverse

Name: erpA

Synonym: PM0458

Alternate gene names: 15602323

Gene position: 533480-533136 (Counterclockwise)

Preceding gene: 15602326

Following gene: 15602322

Centisome position: 23.63

GC content: 41.16

Gene sequence:

>345_bases
ATTATGACAGAGATTTCCGTGCCACTGATCTTTACTGATGCGGCTGCCAACAAAGTAAAAGCCTTAATCAGTGAAGAGGA
AAACCCGAATTTGAAATTACGCGTCTATATTACCGGCGGTGGGTGTAGTGGTTTCCAATATGGTTTTACTTTCGATGAAA
AAGTAAACGACGGTGATTTAACTATTGAGAAATCTGGCGTGCACTTAGTGATCGATCCCATGAGTTTACAATATTTAATT
GGGGGAACCGTGGACTATACTGAGGGCTTAGAAGGTTCTCGTTTCGTTGTGAACAATCCAAACGCCTCAACTACCTGTGG
TTGTGGTTCATCTTTCAGTATTTAA

Upstream 100 bases:

>100_bases
ATTATAACATTATCCAACATAAAAATCCTTGATAAATTCTTGAACGAATTAGTCGGTTATTAGATAATACGTCAATTCAG
TTGAAATTATAGCGAGATAA

Downstream 100 bases:

>100_bases
TATGGATTTCCAATTCACATCTCATTTAGGTTCGATAATGGCGAAATGTTCTATGGGACATGAAGCCATTGCAAACTGGT
TTAATAGCGAAGTGCGGTCA

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MMTEISVPLIFTDAAANKVKALISEEENPNLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVHLVIDPMSLQYLI
GGTVDYTEGLEGSRFVVNNPNASTTCGCGSSFSI

Sequences:

>Translated_114_residues
MMTEISVPLIFTDAAANKVKALISEEENPNLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVHLVIDPMSLQYLI
GGTVDYTEGLEGSRFVVNNPNASTTCGCGSSFSI
>Mature_114_residues
MMTEISVPLIFTDAAANKVKALISEEENPNLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVHLVIDPMSLQYLI
GGTVDYTEGLEGSRFVVNNPNASTTCGCGSSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=48.1927710843374, Blast_Score=84, Evalue=2e-17,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=34.9056603773585, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786351, Length=114, Percent_Identity=78.9473684210526, Blast_Score=198, Evalue=7e-53,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=35.4545454545455, Blast_Score=65, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71998452, Length=116, Percent_Identity=42.2413793103448, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193209025, Length=113, Percent_Identity=30.9734513274336, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=113, Percent_Identity=30.0884955752212, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=34.9056603773585, Blast_Score=72, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=49.3975903614458, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24642263, Length=107, Percent_Identity=34.5794392523364, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_PASMU (Q9CNH3)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245395.1
- HSSP:   O67709
- ProteinModelPortal:   Q9CNH3
- SMR:   Q9CNH3
- GeneID:   1243805
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0458
- NMPDR:   fig|272843.1.peg.458
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- ProtClustDB:   PRK13623
- BioCyc:   PMUL272843:PM0458-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12208; Mature: 12208

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTEISVPLIFTDAAANKVKALISEEENPNLKLRVYITGGGCSGFQYGFTFDEKVNDGDL
CCCEEEEEEEEECCCCCCEEEEECCCCCCCEEEEEEEECCCCCCEECCEEECCCCCCCCE
TIEKSGVHLVIDPMSLQYLIGGTVDYTEGLEGSRFVVNNPNASTTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCEEECCCCCCCCEEEEECCCCCCEECCCCCCCC
>Mature Secondary Structure
MMTEISVPLIFTDAAANKVKALISEEENPNLKLRVYITGGGCSGFQYGFTFDEKVNDGDL
CCCEEEEEEEEECCCCCCEEEEECCCCCCCEEEEEEEECCCCCCEECCEEECCCCCCCCE
TIEKSGVHLVIDPMSLQYLIGGTVDYTEGLEGSRFVVNNPNASTTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCEEECCCCCCCCEEEEECCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100