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The map label for this gene is fur [H]

Identifier: 15602217

GI number: 15602217

Start: 413401

End: 413841

Strand: Reverse

Name: fur [H]

Synonym: PM0352

Alternate gene names: 15602217

Gene position: 413841-413401 (Counterclockwise)

Preceding gene: 15602218

Following gene: 15602211

Centisome position: 18.33

GC content: 35.37

Gene sequence:

>441_bases
ATGTCTGAAGAAAATATCAAACTTTTGAAAAAAGCGGGGTTGAAAATCACCGAACCTCGTTTAACGATTTTGGCATTAAT
GCAAGAACATCAAGAAGAACACTTCTCTGCAGAAGATGTGTATAAAATGCTCCTTGAAAGAGGCGAAGAAATTGGTTTAG
CCACAGTTTACCGTGTATTAAACCAATTTGATGAAGCAAAAATTTTGATTCGTCATAATTTTGAAGGCAATAAATCCGTC
TTTGAACTTGCCCCAACTGAACACCACGATCACATTATTTGCGTGGACTGCGGTAAAGTGTTTGAATTTAATGATGACAT
TATTGAAAAACGTCAACGTGAAATTACCAAACAACATGGTATTGAATTAGCCACACACAGTCTGTATCTTTATGGCAAAT
GTAGTAATGTCAAGAAATGCGATGAGAATGGCAAAAAATAA

Upstream 100 bases:

>100_bases
TGAATTAACTGCTGAACGTGTTGAAAAATGGGTGAAGCAAGTGTTTGACGAAATGTGTTTAGCAGAACTTGCTTAATAGC
AAAATAATTAAGGGGCTATT

Downstream 100 bases:

>100_bases
AAACAAGGCGAATTAAATAAAAAGTGCGGTATAAATTTTCAACGTTTATACCGCACTTTTTTAGTAGCCTGTCAATTGTC
AACTTTACGGCTTGTAAATG

Product: hypothetical protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MSEENIKLLKKAGLKITEPRLTILALMQEHQEEHFSAEDVYKMLLERGEEIGLATVYRVLNQFDEAKILIRHNFEGNKSV
FELAPTEHHDHIICVDCGKVFEFNDDIIEKRQREITKQHGIELATHSLYLYGKCSNVKKCDENGKK

Sequences:

>Translated_146_residues
MSEENIKLLKKAGLKITEPRLTILALMQEHQEEHFSAEDVYKMLLERGEEIGLATVYRVLNQFDEAKILIRHNFEGNKSV
FELAPTEHHDHIICVDCGKVFEFNDDIIEKRQREITKQHGIELATHSLYLYGKCSNVKKCDENGKK
>Mature_145_residues
SEENIKLLKKAGLKITEPRLTILALMQEHQEEHFSAEDVYKMLLERGEEIGLATVYRVLNQFDEAKILIRHNFEGNKSVF
ELAPTEHHDHIICVDCGKVFEFNDDIIEKRQREITKQHGIELATHSLYLYGKCSNVKKCDENGKK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=132, Percent_Identity=67.4242424242424, Blast_Score=187, Evalue=2e-49,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16955; Mature: 16823

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEENIKLLKKAGLKITEPRLTILALMQEHQEEHFSAEDVYKMLLERGEEIGLATVYRVL
CCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
NQFDEAKILIRHNFEGNKSVFELAPTEHHDHIICVDCGKVFEFNDDIIEKRQREITKQHG
HHHCCCEEEEEECCCCCCCEEEECCCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHCC
IELATHSLYLYGKCSNVKKCDENGKK
CEEEEEEEEEEECCCCCHHHHCCCCC
>Mature Secondary Structure 
SEENIKLLKKAGLKITEPRLTILALMQEHQEEHFSAEDVYKMLLERGEEIGLATVYRVL
CCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
NQFDEAKILIRHNFEGNKSVFELAPTEHHDHIICVDCGKVFEFNDDIIEKRQREITKQHG
HHHCCCEEEEEECCCCCCCEEEECCCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHCC
IELATHSLYLYGKCSNVKKCDENGKK
CEEEEEEEEEEECCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 9727086 [H]