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The map label for this gene is arcB [H]

Identifier: 15602178

GI number: 15602178

Start: 369103

End: 370959

Strand: Direct

Name: arcB [H]

Synonym: PM0313

Alternate gene names: 15602178

Gene position: 369103-370959 (Clockwise)

Preceding gene: 15602177

Following gene: 15602179

Centisome position: 16.35

GC content: 37.64

Gene sequence:

>1857_bases
ATGAAAAATATTAAATACTTTGCTCAAAAATATGTTGATTGGGTGATTCGTTTGGGACGCTTACGCTTTTCGATTTTAGG
CGTGATCGTGTTGGCGATTTTAGCACTCTGTACACAAGCCTTATTAAGTTTGTTTATTATTGGTGAAGTGTATTGGGTTG
ATATGATCCGATCTGTTGTATTTGGTCTGATTTCTGCTCCCTTTGTCATTTATTTTTTCACGGTGCTGGTGGAAAAATTA
GAACGTTCGCGTTTAGGGCTTGCCAAAATGGTTGAGAATTTACGCAAAGAAGTGTCGGAACGGGTTTTAGCTGAGAAAAA
ACTCTCTATTGCGTTAGATAATATTGAGAAAACCAGTCGGGATAAAACGCGCTTAATGGCAACGATCAGTCATGAATTAC
GCACTCCATTAAATGGTATTATTGGCTTAAGCCGTATTTTACTCGATGAAAAACTAACGGAAACGCAACAAAATTATTTG
AAAACGATTCATGTGAGTGCTATTTCATTAGGACATATTTTTAGTGACATCATTGATTTAGAAAAAATTGATGCCCGCCG
TATTGAGCTGAATGCGAAAGCCGTAGAGTTAAATAGTTTTCTCAATGATATTAGTAATGTTGCTCGTTTATTAGCACAGC
AAAAAAAACTCGCTTTTCAACTTGTGACAGACAAAAATTTACCAACTTGGTTTATGGTTGATTATGCTCGCTTAAGTCAA
ATTTTATGGAATTTGATTGGAAATGCGGTGAAATTTACTCAAGAAGGACGTATCACGCTGAATGTGAAACGTGTGTCGGA
ATATCAAATTTCCTTTAGTGTCAGTGATACTGGGATTGGCATTCCGGCGAATGAATTACCTCGTGTGTTTGAAATGTATT
ATCAAGTACAATCGAGTGGGCACAAACCACTTGGTAGTGGCATTGGATTAGCAATTTCTCAAACCATTGCCCAATTGATG
GGAGGTGATTTATATGCAACGAGCGAAATGGGGAAAGGATCTTGTTTTACACTGATGTTGCCAGTTAAAGAAGTTGAAAA
GCCAGTCCGCGTACAAAATCAAATGCCAAGTACCTTAAATATTCTCTTAGTTGAAGATATTGAGGTAAATGTGGTGGTAG
CAAAATCCGTACTTGAAAAACTAGGCTATGTGGTTGATGTTGCGATGACAGGACAGCAAGCCATTGAGAAATTTGAACAG
CAGTATTATGATTTGCTATTACTTGATATTCAATTGCCCGATATGTCAGGTTTTGCAGTGGCGAAATATTTACGGGAAGG
TTATGAGGATGGGCGGTATGATTTTTTACCACCTTTAATTGCATTAACTGCCAATGTAATGCACGACAAAAAAGAATATC
AAGCGCAAGGTATGGACGATGTATTACGTAAACCTTTATCGATCGAGGAGTTAACTGCTTGTTTAGTCGAGTATTTTGGT
CATGATGTTTCTCTGTGCTTGGAAACACCAACAACACATCAGATTACGCAAGACGCCACTCATTTTGATGTGAAAATGTT
GAGTGAATTAGTTGAGATGCTAGGCACAGATTTTGTATTAAAGAATTTAGCTTTATTTAAAGAAACGATGCCGGAATATA
TGCAAGCATTAATGACTGCATATTCTGTTTATCAACAAGATGAAAGTCAAAAAGCCGATGTCTTGTCTTGTGCGCATAAA
ATAAAAGGTGCAGCGGCTTCGGTTGGCTTAAAACGAATACAGCAAATTGCGGCACAAGCGCAGGATCCAGAGCAAGGTGA
ATGGACAGAGAACATTCACGATTGGGTACAACAATTAGCACAATATTGGTTATTGGATGTTGAAGCGCTAGAACGTTATT
TAAATAAATCGGTATAA

Upstream 100 bases:

>100_bases
ACAATTGGATTGGCACTATAACGAAGTCTATGGATTTTGGTGAAGAAGACATAGTGGTACAATAAGCGCAGTTGTTTAGA
AAAATAAAGGCAGAAATCAG

Downstream 100 bases:

>100_bases
ATAAAACGATTTTAATTGTGTTGTGTGTTATTAAATTGAATAAAAATAAATTGGTGTAAAATAGAATATTAATTATTTAA
ACTCATAAGAAATAAATGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MKNIKYFAQKYVDWVIRLGRLRFSILGVIVLAILALCTQALLSLFIIGEVYWVDMIRSVVFGLISAPFVIYFFTVLVEKL
ERSRLGLAKMVENLRKEVSERVLAEKKLSIALDNIEKTSRDKTRLMATISHELRTPLNGIIGLSRILLDEKLTETQQNYL
KTIHVSAISLGHIFSDIIDLEKIDARRIELNAKAVELNSFLNDISNVARLLAQQKKLAFQLVTDKNLPTWFMVDYARLSQ
ILWNLIGNAVKFTQEGRITLNVKRVSEYQISFSVSDTGIGIPANELPRVFEMYYQVQSSGHKPLGSGIGLAISQTIAQLM
GGDLYATSEMGKGSCFTLMLPVKEVEKPVRVQNQMPSTLNILLVEDIEVNVVVAKSVLEKLGYVVDVAMTGQQAIEKFEQ
QYYDLLLLDIQLPDMSGFAVAKYLREGYEDGRYDFLPPLIALTANVMHDKKEYQAQGMDDVLRKPLSIEELTACLVEYFG
HDVSLCLETPTTHQITQDATHFDVKMLSELVEMLGTDFVLKNLALFKETMPEYMQALMTAYSVYQQDESQKADVLSCAHK
IKGAAASVGLKRIQQIAAQAQDPEQGEWTENIHDWVQQLAQYWLLDVEALERYLNKSV

Sequences:

>Translated_618_residues
MKNIKYFAQKYVDWVIRLGRLRFSILGVIVLAILALCTQALLSLFIIGEVYWVDMIRSVVFGLISAPFVIYFFTVLVEKL
ERSRLGLAKMVENLRKEVSERVLAEKKLSIALDNIEKTSRDKTRLMATISHELRTPLNGIIGLSRILLDEKLTETQQNYL
KTIHVSAISLGHIFSDIIDLEKIDARRIELNAKAVELNSFLNDISNVARLLAQQKKLAFQLVTDKNLPTWFMVDYARLSQ
ILWNLIGNAVKFTQEGRITLNVKRVSEYQISFSVSDTGIGIPANELPRVFEMYYQVQSSGHKPLGSGIGLAISQTIAQLM
GGDLYATSEMGKGSCFTLMLPVKEVEKPVRVQNQMPSTLNILLVEDIEVNVVVAKSVLEKLGYVVDVAMTGQQAIEKFEQ
QYYDLLLLDIQLPDMSGFAVAKYLREGYEDGRYDFLPPLIALTANVMHDKKEYQAQGMDDVLRKPLSIEELTACLVEYFG
HDVSLCLETPTTHQITQDATHFDVKMLSELVEMLGTDFVLKNLALFKETMPEYMQALMTAYSVYQQDESQKADVLSCAHK
IKGAAASVGLKRIQQIAAQAQDPEQGEWTENIHDWVQQLAQYWLLDVEALERYLNKSV
>Mature_618_residues
MKNIKYFAQKYVDWVIRLGRLRFSILGVIVLAILALCTQALLSLFIIGEVYWVDMIRSVVFGLISAPFVIYFFTVLVEKL
ERSRLGLAKMVENLRKEVSERVLAEKKLSIALDNIEKTSRDKTRLMATISHELRTPLNGIIGLSRILLDEKLTETQQNYL
KTIHVSAISLGHIFSDIIDLEKIDARRIELNAKAVELNSFLNDISNVARLLAQQKKLAFQLVTDKNLPTWFMVDYARLSQ
ILWNLIGNAVKFTQEGRITLNVKRVSEYQISFSVSDTGIGIPANELPRVFEMYYQVQSSGHKPLGSGIGLAISQTIAQLM
GGDLYATSEMGKGSCFTLMLPVKEVEKPVRVQNQMPSTLNILLVEDIEVNVVVAKSVLEKLGYVVDVAMTGQQAIEKFEQ
QYYDLLLLDIQLPDMSGFAVAKYLREGYEDGRYDFLPPLIALTANVMHDKKEYQAQGMDDVLRKPLSIEELTACLVEYFG
HDVSLCLETPTTHQITQDATHFDVKMLSELVEMLGTDFVLKNLALFKETMPEYMQALMTAYSVYQQDESQKADVLSCAHK
IKGAAASVGLKRIQQIAAQAQDPEQGEWTENIHDWVQQLAQYWLLDVEALERYLNKSV

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=513, Percent_Identity=49.1228070175439, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI87081816, Length=524, Percent_Identity=29.0076335877863, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1788713, Length=492, Percent_Identity=28.6585365853659, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1789149, Length=394, Percent_Identity=28.6802030456853, Blast_Score=165, Evalue=9e-42,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=34.7826086956522, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=30.2222222222222, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=27.7272727272727, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=30.1310043668122, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=25.8620689655172, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790861, Length=225, Percent_Identity=28, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87082128, Length=312, Percent_Identity=27.8846153846154, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=218, Percent_Identity=26.1467889908257, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=24.8908296943231, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=25.4310344827586, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1790437, Length=133, Percent_Identity=30.0751879699248, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=165, Percent_Identity=31.5151515151515, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69916; Mature: 69916

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIKYFAQKYVDWVIRLGRLRFSILGVIVLAILALCTQALLSLFIIGEVYWVDMIRSVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLISAPFVIYFFTVLVEKLERSRLGLAKMVENLRKEVSERVLAEKKLSIALDNIEKTSR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKTRLMATISHELRTPLNGIIGLSRILLDEKLTETQQNYLKTIHVSAISLGHIFSDIIDL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKIDARRIELNAKAVELNSFLNDISNVARLLAQQKKLAFQLVTDKNLPTWFMVDYARLSQ
HHCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHH
ILWNLIGNAVKFTQEGRITLNVKRVSEYQISFSVSDTGIGIPANELPRVFEMYYQVQSSG
HHHHHHHHHHHEECCCCEEEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCC
HKPLGSGIGLAISQTIAQLMGGDLYATSEMGKGSCFTLMLPVKEVEKPVRVQNQMPSTLN
CCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECHHHCCCHHHHHHCCCCCEE
ILLVEDIEVNVVVAKSVLEKLGYVVDVAMTGQQAIEKFEQQYYDLLLLDIQLPDMSGFAV
EEEEECCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEEECCCCCHHHH
AKYLREGYEDGRYDFLPPLIALTANVMHDKKEYQAQGMDDVLRKPLSIEELTACLVEYFG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHC
HDVSLCLETPTTHQITQDATHFDVKMLSELVEMLGTDFVLKNLALFKETMPEYMQALMTA
CCEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YSVYQQDESQKADVLSCAHKIKGAAASVGLKRIQQIAAQAQDPEQGEWTENIHDWVQQLA
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
QYWLLDVEALERYLNKSV
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNIKYFAQKYVDWVIRLGRLRFSILGVIVLAILALCTQALLSLFIIGEVYWVDMIRSVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLISAPFVIYFFTVLVEKLERSRLGLAKMVENLRKEVSERVLAEKKLSIALDNIEKTSR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKTRLMATISHELRTPLNGIIGLSRILLDEKLTETQQNYLKTIHVSAISLGHIFSDIIDL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKIDARRIELNAKAVELNSFLNDISNVARLLAQQKKLAFQLVTDKNLPTWFMVDYARLSQ
HHCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHH
ILWNLIGNAVKFTQEGRITLNVKRVSEYQISFSVSDTGIGIPANELPRVFEMYYQVQSSG
HHHHHHHHHHHEECCCCEEEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCC
HKPLGSGIGLAISQTIAQLMGGDLYATSEMGKGSCFTLMLPVKEVEKPVRVQNQMPSTLN
CCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECHHHCCCHHHHHHCCCCCEE
ILLVEDIEVNVVVAKSVLEKLGYVVDVAMTGQQAIEKFEQQYYDLLLLDIQLPDMSGFAV
EEEEECCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEEECCCCCHHHH
AKYLREGYEDGRYDFLPPLIALTANVMHDKKEYQAQGMDDVLRKPLSIEELTACLVEYFG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHC
HDVSLCLETPTTHQITQDATHFDVKMLSELVEMLGTDFVLKNLALFKETMPEYMQALMTA
CCEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YSVYQQDESQKADVLSCAHKIKGAAASVGLKRIQQIAAQAQDPEQGEWTENIHDWVQQLA
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
QYWLLDVEALERYLNKSV
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]