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The map label for this gene is dppC [H]

Identifier: 15602103

GI number: 15602103

Start: 268708

End: 269601

Strand: Direct

Name: dppC [H]

Synonym: PM0238

Alternate gene names: 15602103

Gene position: 268708-269601 (Clockwise)

Preceding gene: 15602102

Following gene: 15602104

Centisome position: 11.9

GC content: 43.06

Gene sequence:

>894_bases
ATGTCAAGTACGACTACGGTTAGTTCACCCGCCCCAAAAACCCCGTTACAAGAATTCTGGTTTTATTTTAAACAAAATCA
TGGTGCGGTCATTGGACTTACTTTTATTGCAATTGTTTTCTTGGTTTGTGTTTTCGCTGGGGTGATTGCCCCTTTTGATC
CGATTGCACAAGATCGGAGTGCCTTATTGTTACCTCCAGCTTGGCTTGATGGTGGCGATAGTCGCTATTTATTAGGTACA
GATGATATCGGTAGGGATATTTTATCGCGTATTATTTATGGCGCGCGTCTGTCGGTCTTTATTGGCTTAACCATTGTGTT
ATTGTCCTGTTTTTTCGGTGTTATTTTAGGCTTACTCGCCGGCTATTATGGTGGAACAGTCGATATTATCATCATGCGAT
TTGTGGATATTATGTTGGCAATTCCAAGCTTATTATTAACCATTGGGGTTGTCACCATTTTAGGTCCCTCATTAACTAAT
GCCGCGATTGCGATTGCTGTGGTGTCGATTCCAAGTTATGTGCGTTTAACCCGTGCGTCGGTGTTAAGTGAGAAAAATCG
TGATTATGTGATTGCTTCTCGCGTGGCGGGTGCCGGTGTTTTTCGTTTGATGTTTATTGTCATTTTACCGAACTGTTTAG
CCCCTTTAATTGTACAAATGACCATGGGGATTTCTAACGCGATTCTTGAACTGGCGGCGTTAGGTTTCTTGGGGATTGGT
GCGCAGCCACCTACACCAGAATTGGGTACGATGTTAGCGGAATCACGAGGCTTTATGCAAACGGCGCACTGGTTAGTGAC
CATTCCCGGTTTAGCCATTCTTTCTCTTGTCTTGGCGTTTAACTTGATGGGTGATGGTTTACGTGATGCACTTGATCCAA
AATTAAAACAATAA

Upstream 100 bases:

>100_bases
GCCACCTTAATTATTATTGTCAATTTAACAGTTGATGTATTTTATGGCATCGTCAATCCACGTATTCGCCATACTTAATT
TGATTTGATTGGAGTGAAAA

Downstream 100 bases:

>100_bases
GGTGGGCAGCATGGCGTTATTAAATGTAGAAAATCTTTCGGTGCATTTTGGTGATGAAAATACCCCTTTTAAAGCGGTGG
ATCGCGTCAGTTACACGGTC

Product: hypothetical protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSSTTTVSSPAPKTPLQEFWFYFKQNHGAVIGLTFIAIVFLVCVFAGVIAPFDPIAQDRSALLLPPAWLDGGDSRYLLGT
DDIGRDILSRIIYGARLSVFIGLTIVLLSCFFGVILGLLAGYYGGTVDIIIMRFVDIMLAIPSLLLTIGVVTILGPSLTN
AAIAIAVVSIPSYVRLTRASVLSEKNRDYVIASRVAGAGVFRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIG
AQPPTPELGTMLAESRGFMQTAHWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ

Sequences:

>Translated_297_residues
MSSTTTVSSPAPKTPLQEFWFYFKQNHGAVIGLTFIAIVFLVCVFAGVIAPFDPIAQDRSALLLPPAWLDGGDSRYLLGT
DDIGRDILSRIIYGARLSVFIGLTIVLLSCFFGVILGLLAGYYGGTVDIIIMRFVDIMLAIPSLLLTIGVVTILGPSLTN
AAIAIAVVSIPSYVRLTRASVLSEKNRDYVIASRVAGAGVFRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIG
AQPPTPELGTMLAESRGFMQTAHWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ
>Mature_296_residues
SSTTTVSSPAPKTPLQEFWFYFKQNHGAVIGLTFIAIVFLVCVFAGVIAPFDPIAQDRSALLLPPAWLDGGDSRYLLGTD
DIGRDILSRIIYGARLSVFIGLTIVLLSCFFGVILGLLAGYYGGTVDIIIMRFVDIMLAIPSLLLTIGVVTILGPSLTNA
AIAIAVVSIPSYVRLTRASVLSEKNRDYVIASRVAGAGVFRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIGA
QPPTPELGTMLAESRGFMQTAHWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=297, Percent_Identity=65.6565656565657, Blast_Score=353, Evalue=7e-99,
Organism=Escherichia coli, GI1787054, Length=285, Percent_Identity=42.8070175438597, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1787760, Length=296, Percent_Identity=41.8918918918919, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787549, Length=291, Percent_Identity=38.8316151202749, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1789889, Length=246, Percent_Identity=39.8373983739837, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1787498, Length=272, Percent_Identity=31.6176470588235, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788505, Length=217, Percent_Identity=33.1797235023041, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31725; Mature: 31594

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTTTVSSPAPKTPLQEFWFYFKQNHGAVIGLTFIAIVFLVCVFAGVIAPFDPIAQDRS
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
ALLLPPAWLDGGDSRYLLGTDDIGRDILSRIIYGARLSVFIGLTIVLLSCFFGVILGLLA
CEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYYGGTVDIIIMRFVDIMLAIPSLLLTIGVVTILGPSLTNAAIAIAVVSIPSYVRLTRAS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VLSEKNRDYVIASRVAGAGVFRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIG
HHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AQPPTPELGTMLAESRGFMQTAHWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SSTTTVSSPAPKTPLQEFWFYFKQNHGAVIGLTFIAIVFLVCVFAGVIAPFDPIAQDRS
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
ALLLPPAWLDGGDSRYLLGTDDIGRDILSRIIYGARLSVFIGLTIVLLSCFFGVILGLLA
CEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYYGGTVDIIIMRFVDIMLAIPSLLLTIGVVTILGPSLTNAAIAIAVVSIPSYVRLTRAS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VLSEKNRDYVIASRVAGAGVFRLMFIVILPNCLAPLIVQMTMGISNAILELAALGFLGIG
HHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AQPPTPELGTMLAESRGFMQTAHWLVTIPGLAILSLVLAFNLMGDGLRDALDPKLKQ
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]