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The map label for this gene is dipZ [H]

Identifier: 15602086

GI number: 15602086

Start: 244510

End: 246270

Strand: Direct

Name: dipZ [H]

Synonym: PM0221

Alternate gene names: 15602086

Gene position: 244510-246270 (Clockwise)

Preceding gene: 15602083

Following gene: 15602087

Centisome position: 10.83

GC content: 39.75

Gene sequence:

>1761_bases
ATGTTGTCGTGGAATGACATGGTTTTGCTTATGAAAAAAATATTTTTTATTTTCTTTTTAATTTGGACAAGTTTATCCGT
CAATGCGGGCGTATTTGATAAAAAAAACGCCTTTTTGAAAGCGGAACAAGCATTTGTCTTCACAGAAAGCCAGCAGAATG
ACAGGTTATCTTTAAATTGGGATATTGCTTCTGGTTATTATCTGTATAAAAAAAGTCTTGAAATAAAAGGGGAGAATGGG
CAACTGTTTATCCCTCAACTGCCGTTAGCGGAAATACATCAAGATGATTTTTTTGGTGACGTTGAGATTTATCGTCATCA
ATTGACCTTTTCTTTGCCTTTTACTCAGTTATCTGCGACGAAACAAGTTGAAATTACTTATCAAGGCTGCACAGAAGGTT
TTTGCTATCCACCTGAAACCCGAGTGATTGCGTTAACCTCGTTAGAGAGGGAATCTGGGCAAATTTCAAGCGCGGTATTG
AAAGAAGAGAGTGTACTTTCTGAACTACCATTAGCAGAGCAAGATCGTTTAGCTGCAAAGTTGATCGAGAGTAAATATGC
GGTCTTTTGGTTTTTCTTGTTTGGGCTGGGACTCGCTTTTACTCCCTGTGTTTTGCCGATGCTGCCTTTATTGTCAGCTA
TTGTCATTGGTCGTGAACAGCGTCCGAGTACAGCCAAAGCGTTCGGATTAAGCGTTGTGTATGTACAAGGGATGGCGTTG
ACTTATACCTTGCTTGGTTTAATTGTGGCAGCGATTGGTTTACCTTTTCAAGTGGCATTACAAAGCCCTTATGTCTTATT
AACGTTATCCGCGATTTTTGTGTTGCTCGCTTTATCTATGTTTGGGCTATTCACTTTGCAATTACCTGTCAGCTTGCAAA
CCAAATTAACCCAATATAGCCAGCAGCAGAAATCAGGGGTATTTGGTGGGGTGTTTGTGATGGGAATGATTGCAGGCTTA
GTCGCGTCACCTTGCACCTCTGCACCATTATCCGGCGCATTACTTTATGTGGCGCAAAGTGGTGATTTATTCACCGGTGC
GATCACCTTATATTTATTAGCCTTAGGGATGGGCTTACCACTCATTTTTATTACTGTCTTTGGTAATAACATCTTGCCAA
AATCAGGTAATTGGATGATTCAAGTGAAAAATGCGTTTGGTTTTGTGTTGTTAGCCTTGCCGATCTTTTTAATTTCGCGT
GTGTTTCCTGAAATCGAAATGCCATTATGGTTCAGTTTAGCGTTTGCGTTCTCGCTATGGTTGTTGTATCAATTCAGAAA
TAATAAAGGGGTATGGGTATTCACTTTTATCCTTGGTGTAATGGGATATTTATATTATAGCTATGCAATGAACCGACATA
CGCCAGCACATCAGACGACTTCTCTGTCTCAATTTGAACGCATTACCAGTTATGCCCAATTACAACAAGTGTTAAGCAAG
AATCCTAACTCTCTGGCGATGTTAGATTTATATGCGGATTGGTGTGTTGCCTGTAAAGAGTTTGAAACGCATACCTTTAG
CGATGTTGCTGTACAGAAAGCATTTACCGATGTTTTACTTTTACAAGTTGATATGACGAAGAACAGTGAGGCGAATCGGG
AACTTATGCAAAAGCTTCACGTCATTGGTTTGCCTACCTTGATTTTCTTTAATCAACAAGGTCAGGAAATTGAAGGCTCA
AGAATAACAGGCTTTATGCAAGCCAGCCCTTTTGTGGATTGGTTACAAAAAATGAAGTCTATTCAGCCAATTAGCCAATA
A

Upstream 100 bases:

>100_bases
TATTTTTTATGGGAAAATAAGTGATCTCAGAATCCGTCACAGAGATAAACGGATTGTAATGTTTGTAATAATATGAAAAA
TAAGTCGTTTTTATTATTTT

Downstream 100 bases:

>100_bases
GGAAGAGGCTTCCTCTTATCTTTGTGAGCGCTAAAACAATACAGCTTATTTTTATGATGAGAGAAATAAGCTGTTTTTTT
ATTGAAAATCGTTACACAAG

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MLSWNDMVLLMKKIFFIFFLIWTSLSVNAGVFDKKNAFLKAEQAFVFTESQQNDRLSLNWDIASGYYLYKKSLEIKGENG
QLFIPQLPLAEIHQDDFFGDVEIYRHQLTFSLPFTQLSATKQVEITYQGCTEGFCYPPETRVIALTSLERESGQISSAVL
KEESVLSELPLAEQDRLAAKLIESKYAVFWFFLFGLGLAFTPCVLPMLPLLSAIVIGREQRPSTAKAFGLSVVYVQGMAL
TYTLLGLIVAAIGLPFQVALQSPYVLLTLSAIFVLLALSMFGLFTLQLPVSLQTKLTQYSQQQKSGVFGGVFVMGMIAGL
VASPCTSAPLSGALLYVAQSGDLFTGAITLYLLALGMGLPLIFITVFGNNILPKSGNWMIQVKNAFGFVLLALPIFLISR
VFPEIEMPLWFSLAFAFSLWLLYQFRNNKGVWVFTFILGVMGYLYYSYAMNRHTPAHQTTSLSQFERITSYAQLQQVLSK
NPNSLAMLDLYADWCVACKEFETHTFSDVAVQKAFTDVLLLQVDMTKNSEANRELMQKLHVIGLPTLIFFNQQGQEIEGS
RITGFMQASPFVDWLQKMKSIQPISQ

Sequences:

>Translated_586_residues
MLSWNDMVLLMKKIFFIFFLIWTSLSVNAGVFDKKNAFLKAEQAFVFTESQQNDRLSLNWDIASGYYLYKKSLEIKGENG
QLFIPQLPLAEIHQDDFFGDVEIYRHQLTFSLPFTQLSATKQVEITYQGCTEGFCYPPETRVIALTSLERESGQISSAVL
KEESVLSELPLAEQDRLAAKLIESKYAVFWFFLFGLGLAFTPCVLPMLPLLSAIVIGREQRPSTAKAFGLSVVYVQGMAL
TYTLLGLIVAAIGLPFQVALQSPYVLLTLSAIFVLLALSMFGLFTLQLPVSLQTKLTQYSQQQKSGVFGGVFVMGMIAGL
VASPCTSAPLSGALLYVAQSGDLFTGAITLYLLALGMGLPLIFITVFGNNILPKSGNWMIQVKNAFGFVLLALPIFLISR
VFPEIEMPLWFSLAFAFSLWLLYQFRNNKGVWVFTFILGVMGYLYYSYAMNRHTPAHQTTSLSQFERITSYAQLQQVLSK
NPNSLAMLDLYADWCVACKEFETHTFSDVAVQKAFTDVLLLQVDMTKNSEANRELMQKLHVIGLPTLIFFNQQGQEIEGS
RITGFMQASPFVDWLQKMKSIQPISQ
>Mature_586_residues
MLSWNDMVLLMKKIFFIFFLIWTSLSVNAGVFDKKNAFLKAEQAFVFTESQQNDRLSLNWDIASGYYLYKKSLEIKGENG
QLFIPQLPLAEIHQDDFFGDVEIYRHQLTFSLPFTQLSATKQVEITYQGCTEGFCYPPETRVIALTSLERESGQISSAVL
KEESVLSELPLAEQDRLAAKLIESKYAVFWFFLFGLGLAFTPCVLPMLPLLSAIVIGREQRPSTAKAFGLSVVYVQGMAL
TYTLLGLIVAAIGLPFQVALQSPYVLLTLSAIFVLLALSMFGLFTLQLPVSLQTKLTQYSQQQKSGVFGGVFVMGMIAGL
VASPCTSAPLSGALLYVAQSGDLFTGAITLYLLALGMGLPLIFITVFGNNILPKSGNWMIQVKNAFGFVLLALPIFLISR
VFPEIEMPLWFSLAFAFSLWLLYQFRNNKGVWVFTFILGVMGYLYYSYAMNRHTPAHQTTSLSQFERITSYAQLQQVLSK
NPNSLAMLDLYADWCVACKEFETHTFSDVAVQKAFTDVLLLQVDMTKNSEANRELMQKLHVIGLPTLIFFNQQGQEIEGS
RITGFMQASPFVDWLQKMKSIQPISQ

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=579, Percent_Identity=48.1865284974093, Blast_Score=515, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 65670; Mature: 65670

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSWNDMVLLMKKIFFIFFLIWTSLSVNAGVFDKKNAFLKAEQAFVFTESQQNDRLSLNW
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECEEEEEECCCCCCEEEEEE
DIASGYYLYKKSLEIKGENGQLFIPQLPLAEIHQDDFFGDVEIYRHQLTFSLPFTQLSAT
EECCCEEEEEEEEEEECCCCCEEECCCCHHHHCCCCCCCCHHHEEEEEEEECCHHHHCCC
KQVEITYQGCTEGFCYPPETRVIALTSLERESGQISSAVLKEESVLSELPLAEQDRLAAK
EEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
LIESKYAVFWFFLFGLGLAFTPCVLPMLPLLSAIVIGREQRPSTAKAFGLSVVYVQGMAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCEEEEEHHHHHH
TYTLLGLIVAAIGLPFQVALQSPYVLLTLSAIFVLLALSMFGLFTLQLPVSLQTKLTQYS
HHHHHHHHHHHHCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHH
QQQKSGVFGGVFVMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAITLYLLALGMGLP
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCC
LIFITVFGNNILPKSGNWMIQVKNAFGFVLLALPIFLISRVFPEIEMPLWFSLAFAFSLW
EEEHEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LLYQFRNNKGVWVFTFILGVMGYLYYSYAMNRHTPAHQTTSLSQFERITSYAQLQQVLSK
HHHHEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
NPNSLAMLDLYADWCVACKEFETHTFSDVAVQKAFTDVLLLQVDMTKNSEANRELMQKLH
CCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHH
VIGLPTLIFFNQQGQEIEGSRITGFMQASPFVDWLQKMKSIQPISQ
HHCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSWNDMVLLMKKIFFIFFLIWTSLSVNAGVFDKKNAFLKAEQAFVFTESQQNDRLSLNW
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECEEEEEECCCCCCEEEEEE
DIASGYYLYKKSLEIKGENGQLFIPQLPLAEIHQDDFFGDVEIYRHQLTFSLPFTQLSAT
EECCCEEEEEEEEEEECCCCCEEECCCCHHHHCCCCCCCCHHHEEEEEEEECCHHHHCCC
KQVEITYQGCTEGFCYPPETRVIALTSLERESGQISSAVLKEESVLSELPLAEQDRLAAK
EEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
LIESKYAVFWFFLFGLGLAFTPCVLPMLPLLSAIVIGREQRPSTAKAFGLSVVYVQGMAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCEEEEEHHHHHH
TYTLLGLIVAAIGLPFQVALQSPYVLLTLSAIFVLLALSMFGLFTLQLPVSLQTKLTQYS
HHHHHHHHHHHHCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHH
QQQKSGVFGGVFVMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAITLYLLALGMGLP
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCC
LIFITVFGNNILPKSGNWMIQVKNAFGFVLLALPIFLISRVFPEIEMPLWFSLAFAFSLW
EEEHEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LLYQFRNNKGVWVFTFILGVMGYLYYSYAMNRHTPAHQTTSLSQFERITSYAQLQQVLSK
HHHHEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
NPNSLAMLDLYADWCVACKEFETHTFSDVAVQKAFTDVLLLQVDMTKNSEANRELMQKLH
CCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHH
VIGLPTLIFFNQQGQEIEGSRITGFMQASPFVDWLQKMKSIQPISQ
HHCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]