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The map label for this gene is hflC [H]

Identifier: 15601983

GI number: 15601983

Start: 144432

End: 145319

Strand: Direct

Name: hflC [H]

Synonym: PM0118

Alternate gene names: 15601983

Gene position: 144432-145319 (Clockwise)

Preceding gene: 15601982

Following gene: 15601985

Centisome position: 6.4

GC content: 42.23

Gene sequence:

>888_bases
ATGCGTAAATTTTTAACCCCTGTCATCGTTGTGATTGCTGCAATTTTATATTCCAGCATTGTGATTGTCTCAGAAGGGAC
CCGTGGCATTATGTTGCGTTTTAGTAAAGTCCATCGTGATGCTGATAATAAAGTGGTGGTGTATAATCCGGGTTTACATT
TTAAAATTCCATTTATTGATTCGATCAAAATTTTAGATGCACGTATTCGTACGCTTGATGGTCAAGCGGATCGTTTTGTG
ACCGTTGAGAAGAAAGATCTACTTGTGGATTCTTATGTCAAATGGCGTATTAGTGATTTTGGTCGTTTTTATACGGCGAC
AGGTGGTGGCGATTATGCCCAAGCGTCCAATTTATTACGCCGTAAAGTCAATGACCGTTTACGTTCTGAAACGGGGTCGA
GAACCATTAAAGACATTGTATCAGGCACACGTGGTGAATTGATGGAAGGTGCGCGTAAAGCATTAAATACGGGACCGGAC
AGTACAGCAGAATTAGGCATTGAAGTGGTGGATGTGCGTGTCAAACAAATCAACCTGCCTGATGAAGTGTCTTCATCGAT
TTATCAACGTATGCGTGCAGAACGTGATGCGGTCGCGCGTGAACATCGTTCACAAGGTCGTGAAAAAGCTGCCTTTATTC
AAGCCGATGTGGATCGTAAAGTGACCCTTATTCTGGCAAATGCCAATCGTACTGCACAAGAATTGCGAGGTTCAGGTGAT
GCGACCGCCGCAAAAGTATTTTCTGATGCCTTTTCACAAGAGCCGCAGTTCTATAGTTTTTTAAGAAGTTTAAAAGCCTA
TGAAAGCAGTTTCGCGAATTCAGATAATATGATGATTTTGAAACCGGACAGTGATTTCTTCCGTTTCATGCAAGCACCGA
CGAAATAA

Upstream 100 bases:

>100_bases
TGCGTCCAGTGTTCCGTGCCGAGACACCAAACGTGATGCCTACACAAACATCAACATCGTCAACACGACAAGAAAATACT
CGCCAAGGGAGATTTAACTA

Downstream 100 bases:

>100_bases
GCGAGCAAAGAAAAAGGCGTGAGTTTCAACTCACGCCTTTTTTCATGTGGAGGAGATTAGTCTTCAAGCATGAAGTCTTT
TAAGTATTGGAAAATTTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MRKFLTPVIVVIAAILYSSIVIVSEGTRGIMLRFSKVHRDADNKVVVYNPGLHFKIPFIDSIKILDARIRTLDGQADRFV
TVEKKDLLVDSYVKWRISDFGRFYTATGGGDYAQASNLLRRKVNDRLRSETGSRTIKDIVSGTRGELMEGARKALNTGPD
STAELGIEVVDVRVKQINLPDEVSSSIYQRMRAERDAVAREHRSQGREKAAFIQADVDRKVTLILANANRTAQELRGSGD
ATAAKVFSDAFSQEPQFYSFLRSLKAYESSFANSDNMMILKPDSDFFRFMQAPTK

Sequences:

>Translated_295_residues
MRKFLTPVIVVIAAILYSSIVIVSEGTRGIMLRFSKVHRDADNKVVVYNPGLHFKIPFIDSIKILDARIRTLDGQADRFV
TVEKKDLLVDSYVKWRISDFGRFYTATGGGDYAQASNLLRRKVNDRLRSETGSRTIKDIVSGTRGELMEGARKALNTGPD
STAELGIEVVDVRVKQINLPDEVSSSIYQRMRAERDAVAREHRSQGREKAAFIQADVDRKVTLILANANRTAQELRGSGD
ATAAKVFSDAFSQEPQFYSFLRSLKAYESSFANSDNMMILKPDSDFFRFMQAPTK
>Mature_295_residues
MRKFLTPVIVVIAAILYSSIVIVSEGTRGIMLRFSKVHRDADNKVVVYNPGLHFKIPFIDSIKILDARIRTLDGQADRFV
TVEKKDLLVDSYVKWRISDFGRFYTATGGGDYAQASNLLRRKVNDRLRSETGSRTIKDIVSGTRGELMEGARKALNTGPD
STAELGIEVVDVRVKQINLPDEVSSSIYQRMRAERDAVAREHRSQGREKAAFIQADVDRKVTLILANANRTAQELRGSGD
ATAAKVFSDAFSQEPQFYSFLRSLKAYESSFANSDNMMILKPDSDFFRFMQAPTK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=330, Percent_Identity=55.4545454545455, Blast_Score=360, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 33130; Mature: 33130

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFLTPVIVVIAAILYSSIVIVSEGTRGIMLRFSKVHRDADNKVVVYNPGLHFKIPFID
CCHHHHHHHHHHHHHHHHCEEEEECCCCHHHEEHHHHHCCCCCEEEEECCCCEEEECCCC
SIKILDARIRTLDGQADRFVTVEKKDLLVDSYVKWRISDFGRFYTATGGGDYAQASNLLR
CHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHH
RKVNDRLRSETGSRTIKDIVSGTRGELMEGARKALNTGPDSTAELGIEVVDVRVKQINLP
HHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHCEEEEEEEEEECCCC
DEVSSSIYQRMRAERDAVAREHRSQGREKAAFIQADVDRKVTLILANANRTAQELRGSGD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCEEEEEEECCCHHHHHHCCCCC
ATAAKVFSDAFSQEPQFYSFLRSLKAYESSFANSDNMMILKPDSDFFRFMQAPTK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCC
>Mature Secondary Structure
MRKFLTPVIVVIAAILYSSIVIVSEGTRGIMLRFSKVHRDADNKVVVYNPGLHFKIPFID
CCHHHHHHHHHHHHHHHHCEEEEECCCCHHHEEHHHHHCCCCCEEEEECCCCEEEECCCC
SIKILDARIRTLDGQADRFVTVEKKDLLVDSYVKWRISDFGRFYTATGGGDYAQASNLLR
CHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHH
RKVNDRLRSETGSRTIKDIVSGTRGELMEGARKALNTGPDSTAELGIEVVDVRVKQINLP
HHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHCEEEEEEEEEECCCC
DEVSSSIYQRMRAERDAVAREHRSQGREKAAFIQADVDRKVTLILANANRTAQELRGSGD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCEEEEEEECCCHHHHHHCCCCC
ATAAKVFSDAFSQEPQFYSFLRSLKAYESSFANSDNMMILKPDSDFFRFMQAPTK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]