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The map label for this gene is hslO

Identifier: 30024069

GI number: 30024069

Start: 2034313

End: 2035179

Strand: Direct

Name: hslO

Synonym: L17654

Alternate gene names: 30024069

Gene position: 2034313-2035179 (Clockwise)

Preceding gene: 15673933

Following gene: 15673942

Centisome position: 86.0

GC content: 36.91

Gene sequence:

>867_bases
ATGGATAAAATTATCAAATCAATCTCAAAAAATGGGCATTTCAGAGCTTTTGCTTTGGATTCAACCCTAACTGTGAAAGA
AGCACAGGAACGCCATCAAACATGGCCAACTTCGACGGTTGCCTTAGGTCGTACATTGATTGCTGGACAAATTTTAGGAG
CTAATGAAAAAGGTGATACTAAAATTACAGTTAAAGTTCTGGGTGATGGAGCAATGGGTCCAATCATCGCAGTCGCTGAT
AGCCGCGGCCATGTCAAAGGTTATGTCAAAAATCGTAAACTCGACTATAAAAAAGCTTCAACTGGTGAAGTGTTAGTTGC
TCCTTTTGTTGGTAATGGCTTTTTAGTTGTGGTCAAAGACATGGGGCTTAAACAACCTTATAGTGGTCAAGTTGATTTAA
TTACTGGTGAAATTGGCGAAGACTTAGCTTGGTATTTTTTAAGTTCAGAACAAACTCCTTCTTCTGTTGGTGTGAATGTT
TTGCTTAATGAAGACTCAGATACAGTCAAAATTGCTGGTGGATTTATGTTGCAAGCTTTGCCAGATGCTACTGACGAAGA
AATTACCGAAATTGAACATAATATTAAAAGTATGCCTTCAATTGCAACAATGCTGACCAGTGAAGAACCATTAAAAACGA
TGTTAGACAATATTTATGGCGATATGGAATACAAAAATCTTGGCGAATTTCCTTTGGAATTCAAATGTGATTGTAGTAAG
GAACGTTTCCTTGAAGGCATTAAATCTTTAGGAAGAGAACCAATTGAGGAAATGATAGCCGAGGATCACGGTGCTGAAAT
TATTTGTCAATTCTGTGAAAACAAATATGAGTATTCTGAAGATGAATTAAAAGCACTCCTTAAGTAA

Upstream 100 bases:

>100_bases
AAGGAAAATCTGAGGTTTTTTCTTGCTTTTATATCATTTATTGATTGACAATTTTTGTGCTCTATTGAGGTCAGTTGGGG
TCTTGTGGTACAATAGACTC

Downstream 100 bases:

>100_bases
AATAACTAATTATTTTACTGACAGAAATTCTGTCAGTAAATAGAATTGAGAAAAATGACTGTAAAACTTTTTATTGCTTC
TACATTAGACGGCTATATTG

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MDKIIKSISKNGHFRAFALDSTLTVKEAQERHQTWPTSTVALGRTLIAGQILGANEKGDTKITVKVLGDGAMGPIIAVAD
SRGHVKGYVKNRKLDYKKASTGEVLVAPFVGNGFLVVVKDMGLKQPYSGQVDLITGEIGEDLAWYFLSSEQTPSSVGVNV
LLNEDSDTVKIAGGFMLQALPDATDEEITEIEHNIKSMPSIATMLTSEEPLKTMLDNIYGDMEYKNLGEFPLEFKCDCSK
ERFLEGIKSLGREPIEEMIAEDHGAEIICQFCENKYEYSEDELKALLK

Sequences:

>Translated_288_residues
MDKIIKSISKNGHFRAFALDSTLTVKEAQERHQTWPTSTVALGRTLIAGQILGANEKGDTKITVKVLGDGAMGPIIAVAD
SRGHVKGYVKNRKLDYKKASTGEVLVAPFVGNGFLVVVKDMGLKQPYSGQVDLITGEIGEDLAWYFLSSEQTPSSVGVNV
LLNEDSDTVKIAGGFMLQALPDATDEEITEIEHNIKSMPSIATMLTSEEPLKTMLDNIYGDMEYKNLGEFPLEFKCDCSK
ERFLEGIKSLGREPIEEMIAEDHGAEIICQFCENKYEYSEDELKALLK
>Mature_288_residues
MDKIIKSISKNGHFRAFALDSTLTVKEAQERHQTWPTSTVALGRTLIAGQILGANEKGDTKITVKVLGDGAMGPIIAVAD
SRGHVKGYVKNRKLDYKKASTGEVLVAPFVGNGFLVVVKDMGLKQPYSGQVDLITGEIGEDLAWYFLSSEQTPSSVGVNV
LLNEDSDTVKIAGGFMLQALPDATDEEITEIEHNIKSMPSIATMLTSEEPLKTMLDNIYGDMEYKNLGEFPLEFKCDCSK
ERFLEGIKSLGREPIEEMIAEDHGAEIICQFCENKYEYSEDELKALLK

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=278, Percent_Identity=25.8992805755396, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_LACLA (Q9CE86)

Other databases:

- EMBL:   AE005176
- PIR:   G86869
- RefSeq:   NP_268116.2
- ProteinModelPortal:   Q9CE86
- SMR:   Q9CE86
- GeneID:   1115633
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L17654
- NMPDR:   fig|272623.1.peg.2012
- HOGENOM:   HBG286231
- OMA:   QRHKLSY
- ProtClustDB:   PRK00114
- BioCyc:   LLAC272623:L17654-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31720; Mature: 31720

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIIKSISKNGHFRAFALDSTLTVKEAQERHQTWPTSTVALGRTLIAGQILGANEKGDT
CCHHHHHHCCCCCEEEEEECCCEEHHHHHHHHHCCCCHHHHHHHHHHHCEEECCCCCCCC
KITVKVLGDGAMGPIIAVADSRGHVKGYVKNRKLDYKKASTGEVLVAPFVGNGFLVVVKD
EEEEEEECCCCCCCEEEEECCCCCEEEEEECCEECCCCCCCCCEEEEEEECCCEEEEEEC
MGLKQPYSGQVDLITGEIGEDLAWYFLSSEQTPSSVGVNVLLNEDSDTVKIAGGFMLQAL
CCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEECCEEEEEC
PDATDEEITEIEHNIKSMPSIATMLTSEEPLKTMLDNIYGDMEYKNLGEFPLEFKCDCSK
CCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCCH
ERFLEGIKSLGREPIEEMIAEDHGAEIICQFCENKYEYSEDELKALLK
HHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MDKIIKSISKNGHFRAFALDSTLTVKEAQERHQTWPTSTVALGRTLIAGQILGANEKGDT
CCHHHHHHCCCCCEEEEEECCCEEHHHHHHHHHCCCCHHHHHHHHHHHCEEECCCCCCCC
KITVKVLGDGAMGPIIAVADSRGHVKGYVKNRKLDYKKASTGEVLVAPFVGNGFLVVVKD
EEEEEEECCCCCCCEEEEECCCCCEEEEEECCEECCCCCCCCCEEEEEEECCCEEEEEEC
MGLKQPYSGQVDLITGEIGEDLAWYFLSSEQTPSSVGVNVLLNEDSDTVKIAGGFMLQAL
CCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEECCEEEEEC
PDATDEEITEIEHNIKSMPSIATMLTSEEPLKTMLDNIYGDMEYKNLGEFPLEFKCDCSK
CCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCCH
ERFLEGIKSLGREPIEEMIAEDHGAEIICQFCENKYEYSEDELKALLK
HHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471