BacMap

Definition	Lactococcus lactis subsp. lactis Il1403, complete genome.
Accession	NC_002662
Length	2,365,589

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The map label for this gene is ypaI

Identifier: 30024046

GI number: 30024046

Start: 1508326

End: 1509057

Strand: Direct

Name: ypaI

Synonym: L108008

Alternate gene names: 30024046

Gene position: 1508326-1509057 (Clockwise)

Preceding gene: 15673460

Following gene: 15673465

Centisome position: 63.76

GC content: 36.61

Gene sequence:

>732_bases
ATGTCTAAACCACTTATTGTTATAACAGGAGCAAGTTCAGGATTTGGTGCTGAAATTGCAAAATTATTTAATGCTGATGG
ATTCCCAATGTTGCTTTTAGGTCGTCGTACAGATAAAATCAAAGCCTTGCCCCTTGATTTTACGAATGTCCTTGTGGAAT
CTGTAGATGTCACAGATAAAAAAACTTTTGAAAATGCAATTTCCAAAGCTGAAGAAAAATATGGCAAAACTGATCTTCTA
GTCAATAATGCAGGTGTCATGTTATTAGGAAATGTTCTTAATCAAAATCCAGCAGAATGGAAACAAATGATGGATACTAA
TGTTTTGGGTGTCCTTAATGGAATGCAAATTGTTCTTCCACAAATGGTTGAACGCCAAGGAGGAACAGTAATTAACATGT
CTTCTCTTGCTGGTAAAAAAACTTTTACCAATCACGCCGCTTATGTCGCTTCAAAATTTGGTGTCCATGGTTTAAGTGAA
ACTATCAGAGAGGAAGTTTCTGGTAAAAATGTTCGAATTTCACTTGTTGCACCTGGTGCTGCCGAAACAGAATTATTGAC
ACATGTTACTGACGAAAGTGCCCTAAATGATTATAATCTTTGGAAAGAATCAATGGGTGGTACAACACTTGCTCCTGAAA
GAGTGGCGCAAACCGTGAAATTCATTTATGATATGCCTCAAACGGTCAACATCAGAGAAATTGATATTGCTGCAACCAAT
CAAAATGCTTAA

Upstream 100 bases:

>100_bases
ATCGCCAATTGTATATTTTGTCATTCTTTCTCCTTGACATGGAGTTAACTCCATGTTGTATAATCAGTATATCAAAAAAA
TACTCTTAAGGAGAAATAAA

Downstream 100 bases:

>100_bases
TGTTTAATATTTTAGATAAAAAAAGATACTAGTTAATCGCTAGTATCTTTTTTAGCTATTTATTTCATATTTTATCTAGC
AAATAAGCTCTGTCTTCAAA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSKPLIVITGASSGFGAEIAKLFNADGFPMLLLGRRTDKIKALPLDFTNVLVESVDVTDKKTFENAISKAEEKYGKTDLL
VNNAGVMLLGNVLNQNPAEWKQMMDTNVLGVLNGMQIVLPQMVERQGGTVINMSSLAGKKTFTNHAAYVASKFGVHGLSE
TIREEVSGKNVRISLVAPGAAETELLTHVTDESALNDYNLWKESMGGTTLAPERVAQTVKFIYDMPQTVNIREIDIAATN
QNA

Sequences:

>Translated_243_residues
MSKPLIVITGASSGFGAEIAKLFNADGFPMLLLGRRTDKIKALPLDFTNVLVESVDVTDKKTFENAISKAEEKYGKTDLL
VNNAGVMLLGNVLNQNPAEWKQMMDTNVLGVLNGMQIVLPQMVERQGGTVINMSSLAGKKTFTNHAAYVASKFGVHGLSE
TIREEVSGKNVRISLVAPGAAETELLTHVTDESALNDYNLWKESMGGTTLAPERVAQTVKFIYDMPQTVNIREIDIAATN
QNA
>Mature_242_residues
SKPLIVITGASSGFGAEIAKLFNADGFPMLLLGRRTDKIKALPLDFTNVLVESVDVTDKKTFENAISKAEEKYGKTDLLV
NNAGVMLLGNVLNQNPAEWKQMMDTNVLGVLNGMQIVLPQMVERQGGTVINMSSLAGKKTFTNHAAYVASKFGVHGLSET
IREEVSGKNVRISLVAPGAAETELLTHVTDESALNDYNLWKESMGGTTLAPERVAQTVKFIYDMPQTVNIREIDIAATNQ
NA

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=30.3664921465969, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI4503817, Length=232, Percent_Identity=32.7586206896552, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI40254992, Length=223, Percent_Identity=27.3542600896861, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI109715829, Length=253, Percent_Identity=25.6916996047431, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7706318, Length=191, Percent_Identity=27.2251308900524, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI157739938, Length=227, Percent_Identity=28.1938325991189, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542939, Length=210, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI22507405, Length=212, Percent_Identity=31.1320754716981, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI4758504, Length=199, Percent_Identity=28.1407035175879, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI19743808, Length=229, Percent_Identity=30.1310043668122, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=30.3191489361702, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI150247226, Length=239, Percent_Identity=28.8702928870293, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI223718074, Length=199, Percent_Identity=29.1457286432161, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI44680136, Length=190, Percent_Identity=26.8421052631579, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI44680133, Length=190, Percent_Identity=26.8421052631579, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI17738292, Length=190, Percent_Identity=26.8421052631579, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI5031737, Length=187, Percent_Identity=28.8770053475936, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=28.8770053475936, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI32483357, Length=187, Percent_Identity=25.668449197861, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI66933014, Length=165, Percent_Identity=29.6969696969697, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19923817, Length=234, Percent_Identity=21.3675213675214, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI40548397, Length=189, Percent_Identity=29.1005291005291, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI214010158, Length=189, Percent_Identity=29.1005291005291, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI214010156, Length=189, Percent_Identity=29.1005291005291, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI22758144, Length=189, Percent_Identity=29.1005291005291, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI224922801, Length=164, Percent_Identity=29.8780487804878, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7705925, Length=181, Percent_Identity=25.9668508287293, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4557649, Length=188, Percent_Identity=27.1276595744681, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI83715985, Length=174, Percent_Identity=27.5862068965517, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI32455239, Length=186, Percent_Identity=28.494623655914, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI5031765, Length=186, Percent_Identity=28.494623655914, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI50726952, Length=188, Percent_Identity=28.1914893617021, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787820, Length=240, Percent_Identity=28.75, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI87082100, Length=198, Percent_Identity=31.3131313131313, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=27.3684210526316, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786701, Length=230, Percent_Identity=27.8260869565217, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788459, Length=185, Percent_Identity=30.2702702702703, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787526, Length=198, Percent_Identity=29.2929292929293, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786812, Length=241, Percent_Identity=24.0663900414938, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790717, Length=200, Percent_Identity=27.5, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082160, Length=187, Percent_Identity=25.1336898395722, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787905, Length=193, Percent_Identity=27.979274611399, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=190, Percent_Identity=28.4210526315789, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=207, Percent_Identity=28.5024154589372, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115534660, Length=200, Percent_Identity=29.5, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=244, Percent_Identity=25.8196721311475, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=237, Percent_Identity=27.4261603375527, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=197, Percent_Identity=28.9340101522843, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=237, Percent_Identity=25.7383966244726, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=229, Percent_Identity=23.5807860262009, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17570069, Length=181, Percent_Identity=29.2817679558011, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=243, Percent_Identity=25.5144032921811, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=255, Percent_Identity=24.7058823529412, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=237, Percent_Identity=26.1603375527426, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=242, Percent_Identity=25.6198347107438, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=195, Percent_Identity=25.6410256410256, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=242, Percent_Identity=23.1404958677686, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=27.6381909547739, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=188, Percent_Identity=27.1276595744681, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323882, Length=254, Percent_Identity=30.7086614173228, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322067, Length=187, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=229, Percent_Identity=24.0174672489083, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=215, Percent_Identity=26.046511627907, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=26.984126984127, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24641232, Length=245, Percent_Identity=30.6122448979592, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21358495, Length=189, Percent_Identity=29.1005291005291, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI23397609, Length=179, Percent_Identity=30.1675977653631, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571387, Length=249, Percent_Identity=28.1124497991968, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357041, Length=186, Percent_Identity=30.6451612903226, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI116007236, Length=245, Percent_Identity=28.9795918367347, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=187, Percent_Identity=31.0160427807487, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24641388, Length=248, Percent_Identity=29.4354838709677, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI28571526, Length=192, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281364494, Length=247, Percent_Identity=27.1255060728745, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007234, Length=245, Percent_Identity=28.1632653061224, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24648693, Length=244, Percent_Identity=27.0491803278689, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355889, Length=244, Percent_Identity=27.0491803278689, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281364892, Length=197, Percent_Identity=28.9340101522843, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI116007238, Length=173, Percent_Identity=31.2138728323699, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24648944, Length=193, Percent_Identity=29.5336787564767, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355319, Length=227, Percent_Identity=26.8722466960352, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=181, Percent_Identity=25.9668508287293, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24640492, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=25.9574468085106, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007232, Length=182, Percent_Identity=31.3186813186813, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639444, Length=229, Percent_Identity=24.0174672489083, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24649181, Length=186, Percent_Identity=28.494623655914, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26345; Mature: 26213

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPLIVITGASSGFGAEIAKLFNADGFPMLLLGRRTDKIKALPLDFTNVLVESVDVTDK
CCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCEEECCCCHHHHHHHHCCCCHH
KTFENAISKAEEKYGKTDLLVNNAGVMLLGNVLNQNPAEWKQMMDTNVLGVLNGMQIVLP
HHHHHHHHHHHHHHCCCEEEECCCCCEEECHHHCCCHHHHHHHHCCHHHHHHCCHHHHHH
QMVERQGGTVINMSSLAGKKTFTNHAAYVASKFGVHGLSETIREEVSGKNVRISLVAPGA
HHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCC
AETELLTHVTDESALNDYNLWKESMGGTTLAPERVAQTVKFIYDMPQTVNIREIDIAATN
CHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECC
QNA
CCC
>Mature Secondary Structure 
SKPLIVITGASSGFGAEIAKLFNADGFPMLLLGRRTDKIKALPLDFTNVLVESVDVTDK
CCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCEEECCCCHHHHHHHHCCCCHH
KTFENAISKAEEKYGKTDLLVNNAGVMLLGNVLNQNPAEWKQMMDTNVLGVLNGMQIVLP
HHHHHHHHHHHHHHCCCEEEECCCCCEEECHHHCCCHHHHHHHHCCHHHHHHCCHHHHHH
QMVERQGGTVINMSSLAGKKTFTNHAAYVASKFGVHGLSETIREEVSGKNVRISLVAPGA
HHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCC
AETELLTHVTDESALNDYNLWKESMGGTTLAPERVAQTVKFIYDMPQTVNIREIDIAATN
CHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECC
QNA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA