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The map label for this gene is yxdE

Identifier: 15674232

GI number: 15674232

Start: 2337792

End: 2338811

Strand: Direct

Name: yxdE

Synonym: L121175

Alternate gene names: 15674232

Gene position: 2337792-2338811 (Clockwise)

Preceding gene: 15674230

Following gene: 15674233

Centisome position: 98.82

GC content: 34.9

Gene sequence:

>1020_bases
ATGTCAAATCAAGAACCAATAGCAAACTACAAATTTAATTATAAAACAACAGCAAATAAAGTTATGAAAAATATTAATCT
TTCAGGAAAAACAATCATCATCACTGGTGGGTATTCTGGTATTGGTTTAGAGATGACCAAACAACTTTCACGTGCTGGAG
CAAAAATTATTATCCCCGCCCGAAGAATGGAGGTAGCCAAGAAAAATTTATCTAAAATAAAAAATATTGACATTCTTCCC
CTTGACCTCACCAATCCAGAAAGCATTCATCAATTTGCCGAAAGTTTTTTGCAAAATAATTCAAAACTAGATATTCTTAT
TAATTCCGCTGGATTAATGTACCTTCCTTTAAAAAGAGATTCCCGAGGAATAGAATATCACTTTGCCACAAACCATCTAG
GCCACTATCAATTAACACTGGAACTTTTACCCGCTTTAAAAAATGCAAAAATCTCAAGAGTTATAAATTTATCCAGTCGT
GCTCAACAAATGACACCATTACTAGAAGATTGGAATTTTGAAAAAATAGAAAACTATAATCCCCAAATAGGCTACCAACA
ATCTAAAACTGCCAACGTTTTATTTTCAATAAAACTAGATGAACTAGGAAAAAAATATGGAATTAGAAGTTTTGCCGTCC
ACCCTGGTATGATTCCAATGACAAATATTGGTCGTCAAAATTCACCAATTACCCCTTGGCTCCGCTACCTAGCCGACTAT
TTTAAATTAATTCATATCCCCGTATTTTTTAATGCACTTAAATCCGGCTTTGACCGAAGTAAATATCGCTATTTAAAAAC
AATCGCTCAAGGTGCCGCAACACCTCTTTGGGCCTCAACAAGCCCTGATTTAGAAGGTAAGGGTGGTCTTTATTGTGAAG
ACCTTAATATTGCCAGACTTATGACATCAGAAGAAGCTAATAATTTTTCTGGAGGCTTACGTCCGCATGCAATAGACCAC
AATGACGCAGATAGACTTTGGCAGATTTCAAAAAATATAACAGGTCTGGATTTTGAATAA

Upstream 100 bases:

>100_bases
TCACTTTTAAAGACAAACCGTCCAAAGTTAATTGTAAAAGTTCTTTTTTGCTATTACACTTGTATCACATAAATATTATA
ACACAAAGGAAAATTTTATT

Downstream 100 bases:

>100_bases
ACCCTTACTATAAAATAAAACTGACCTATTATAAATAGGTCAGTTTATCTATTTTTTCATTAGATGAAACTTATTATACA
TACTACTTTTGATTAAATAA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGAKIIIPARRMEVAKKNLSKIKNIDILP
LDLTNPESIHQFAESFLQNNSKLDILINSAGLMYLPLKRDSRGIEYHFATNHLGHYQLTLELLPALKNAKISRVINLSSR
AQQMTPLLEDWNFEKIENYNPQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADY
FKLIHIPVFFNALKSGFDRSKYRYLKTIAQGAATPLWASTSPDLEGKGGLYCEDLNIARLMTSEEANNFSGGLRPHAIDH
NDADRLWQISKNITGLDFE

Sequences:

>Translated_339_residues
MSNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGAKIIIPARRMEVAKKNLSKIKNIDILP
LDLTNPESIHQFAESFLQNNSKLDILINSAGLMYLPLKRDSRGIEYHFATNHLGHYQLTLELLPALKNAKISRVINLSSR
AQQMTPLLEDWNFEKIENYNPQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADY
FKLIHIPVFFNALKSGFDRSKYRYLKTIAQGAATPLWASTSPDLEGKGGLYCEDLNIARLMTSEEANNFSGGLRPHAIDH
NDADRLWQISKNITGLDFE
>Mature_338_residues
SNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGAKIIIPARRMEVAKKNLSKIKNIDILPL
DLTNPESIHQFAESFLQNNSKLDILINSAGLMYLPLKRDSRGIEYHFATNHLGHYQLTLELLPALKNAKISRVINLSSRA
QQMTPLLEDWNFEKIENYNPQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADYF
KLIHIPVFFNALKSGFDRSKYRYLKTIAQGAATPLWASTSPDLEGKGGLYCEDLNIARLMTSEEANNFSGGLRPHAIDHN
DADRLWQISKNITGLDFE

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706523, Length=342, Percent_Identity=29.2397660818713, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI10190746, Length=330, Percent_Identity=30.9090909090909, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI166795268, Length=319, Percent_Identity=31.3479623824451, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI186928839, Length=323, Percent_Identity=32.1981424148607, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI225579078, Length=338, Percent_Identity=30.1775147928994, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI193804850, Length=274, Percent_Identity=33.2116788321168, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI146231950, Length=324, Percent_Identity=29.320987654321, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI19923931, Length=267, Percent_Identity=31.0861423220974, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI7706318, Length=143, Percent_Identity=32.1678321678322, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=25.296442687747, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786701, Length=133, Percent_Identity=33.8345864661654, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532791, Length=296, Percent_Identity=30.0675675675676, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193207620, Length=339, Percent_Identity=30.0884955752212, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17532805, Length=297, Percent_Identity=32.3232323232323, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71992402, Length=302, Percent_Identity=27.8145695364238, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17505416, Length=289, Percent_Identity=30.4498269896194, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17535059, Length=298, Percent_Identity=27.1812080536913, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17558006, Length=325, Percent_Identity=26.1538461538462, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32565532, Length=229, Percent_Identity=34.4978165938865, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324820, Length=228, Percent_Identity=26.7543859649123, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI22024069, Length=325, Percent_Identity=31.6923076923077, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI28573296, Length=320, Percent_Identity=33.4375, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24586328, Length=319, Percent_Identity=29.153605015674, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45554248, Length=277, Percent_Identity=34.2960288808664, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24640117, Length=277, Percent_Identity=34.2960288808664, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI20129347, Length=306, Percent_Identity=29.4117647058824, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI161076371, Length=282, Percent_Identity=31.5602836879433, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19921754, Length=322, Percent_Identity=29.1925465838509, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24656154, Length=317, Percent_Identity=27.7602523659306, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI19922628, Length=317, Percent_Identity=27.7602523659306, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24647946, Length=337, Percent_Identity=29.3768545994065, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45553409, Length=321, Percent_Identity=29.9065420560748, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647948, Length=321, Percent_Identity=29.9065420560748, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647931, Length=299, Percent_Identity=23.7458193979933, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38281; Mature: 38149

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGAKIIIPA
CCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEH
RRMEVAKKNLSKIKNIDILPLDLTNPESIHQFAESFLQNNSKLDILINSAGLMYLPLKRD
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCC
SRGIEYHFATNHLGHYQLTLELLPALKNAKISRVINLSSRAQQMTPLLEDWNFEKIENYN
CCCEEEEEECCCCCCEEEHHHHHHHHHCCHHHHEEEHHHHHHHHHHHHHCCCCHHHCCCC
PQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADY
CCCCCCCCCCCEEEEEEEHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
FKLIHIPVFFNALKSGFDRSKYRYLKTIAQGAATPLWASTSPDLEGKGGLYCEDLNIARL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHHH
MTSEEANNFSGGLRPHAIDHNDADRLWQISKNITGLDFE
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGAKIIIPA
CCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEH
RRMEVAKKNLSKIKNIDILPLDLTNPESIHQFAESFLQNNSKLDILINSAGLMYLPLKRD
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCC
SRGIEYHFATNHLGHYQLTLELLPALKNAKISRVINLSSRAQQMTPLLEDWNFEKIENYN
CCCEEEEEECCCCCCEEEHHHHHHHHHCCHHHHEEEHHHHHHHHHHHHHCCCCHHHCCCC
PQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADY
CCCCCCCCCCCEEEEEEEHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
FKLIHIPVFFNALKSGFDRSKYRYLKTIAQGAATPLWASTSPDLEGKGGLYCEDLNIARL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHHH
MTSEEANNFSGGLRPHAIDHNDADRLWQISKNITGLDFE
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]