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The map label for this gene is coaD

Identifier: 15674144

GI number: 15674144

Start: 2238505

End: 2239002

Strand: Reverse

Name: coaD

Synonym: L21952

Alternate gene names: 15674144

Gene position: 2239002-2238505 (Counterclockwise)

Preceding gene: 15674145

Following gene: 15674143

Centisome position: 94.65

GC content: 34.54

Gene sequence:

>498_bases
ATGACAGAAAAAATTGGACTCTTTACAGGAACTTTTGACCCACTGACAAATGGTCATTTAGACGTTATCAAACGTGCCAG
TCAACATTTTGATCAACTTTATGTTGGAATTTTTAAAAATGACCAAAAAAATCCACTTTTTCCAACTGATAAACGAGTGG
AAATGCTAGAAGAAGCACTGACAAGTCTGTCAGTAACTCATAAAGTCAAAGTCATCAAACATGAACGTGATTTGACAGTG
AATATTGCTAAAAAACTTGGCGTGACAGCTCTGGTTCGTTCTTTGCGTAATAGCCAAGATTTAGAATATGAAAAAAATAT
GTTCTATTTTAATATGGAGATGACAGGCATTGAAACCATCTTTTTCTTAGCAAAACCAGAACTTGAACCATTAAATTCAA
CACGGATGCGAGAATTACATGCCTTTGGTCAAGATGTCAGTGCTTGGGTTCCAGAAAATGTGAGTCGTGAATTAAGGAAA
TTAGATGAAAAAAAATAA

Upstream 100 bases:

>100_bases
TGACCAGACAAAAAACTTACGGAATTTCTAAAATTTCAATTTATGAATTTTGACTTTTACTGACAGAAATTCTGTCAGTA
AATTAAGAAAGAAAAAAGTA

Downstream 100 bases:

>100_bases
AAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTTATTTTATCCAACGA
GTTACTATGTGGAAATGCCC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTEKIGLFTGTFDPLTNGHLDVIKRASQHFDQLYVGIFKNDQKNPLFPTDKRVEMLEEALTSLSVTHKVKVIKHERDLTV
NIAKKLGVTALVRSLRNSQDLEYEKNMFYFNMEMTGIETIFFLAKPELEPLNSTRMRELHAFGQDVSAWVPENVSRELRK
LDEKK

Sequences:

>Translated_165_residues
MTEKIGLFTGTFDPLTNGHLDVIKRASQHFDQLYVGIFKNDQKNPLFPTDKRVEMLEEALTSLSVTHKVKVIKHERDLTV
NIAKKLGVTALVRSLRNSQDLEYEKNMFYFNMEMTGIETIFFLAKPELEPLNSTRMRELHAFGQDVSAWVPENVSRELRK
LDEKK
>Mature_164_residues
TEKIGLFTGTFDPLTNGHLDVIKRASQHFDQLYVGIFKNDQKNPLFPTDKRVEMLEEALTSLSVTHKVKVIKHERDLTVN
IAKKLGVTALVRSLRNSQDLEYEKNMFYFNMEMTGIETIFFLAKPELEPLNSTRMRELHAFGQDVSAWVPENVSRELRKL
DEKK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=33.7579617834395, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 19128; Mature: 18997

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKIGLFTGTFDPLTNGHLDVIKRASQHFDQLYVGIFKNDQKNPLFPTDKRVEMLEEAL
CCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TSLSVTHKVKVIKHERDLTVNIAKKLGVTALVRSLRNSQDLEYEKNMFYFNMEMTGIETI
HHHHHHHHHEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEE
FFLAKPELEPLNSTRMRELHAFGQDVSAWVPENVSRELRKLDEKK
EEEECCCCCCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TEKIGLFTGTFDPLTNGHLDVIKRASQHFDQLYVGIFKNDQKNPLFPTDKRVEMLEEAL
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TSLSVTHKVKVIKHERDLTVNIAKKLGVTALVRSLRNSQDLEYEKNMFYFNMEMTGIETI
HHHHHHHHHEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEE
FFLAKPELEPLNSTRMRELHAFGQDVSAWVPENVSRELRKLDEKK
EEEECCCCCCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA