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The map label for this gene is yvhA

Identifier: 15674084

GI number: 15674084

Start: 2170994

End: 2172196

Strand: Reverse

Name: yvhA

Synonym: L154438

Alternate gene names: 15674084

Gene position: 2172196-2170994 (Counterclockwise)

Preceding gene: 15674085

Following gene: 15674082

Centisome position: 91.82

GC content: 36.74

Gene sequence:

>1203_bases
ATGATTGTTGCTCACCTTAGTCTTTCTGCCGTAGCAGCTGTTTCTTTGGCTAATAATCTCATCACGGTCTATCAGGCGAT
TTTTATTGCTTTGGGAACAATTGTTTCAAGTTTATTTGCCAAAGTGCTTATTGCAAAGAAGGTAGAGGAAAACCCGAAAA
GATTAATTAATTCTGCTACCAAACTGACTTTTTTAATTGGTCTTGCCTTGGGGGTTGTTTCAGTTGTGGGAGCACGACCT
ATTCTCTATTTACTTGGTGCTCGTCAGCAGGTTTTAGAGCTTTCCATTATTTATCTTAGTTTAGTAGGTGGCTTGATTGT
CCTTTTGGCTTTAATGACGACTTTTGGAGCCTTTCTACGGGCTGATGGAAATACAAAGACACCGATGTGGGCAAGTTTTT
TTGCCAGTCTTCTAAATTTGATACTGTCAATTGTCTTTATTTTTGTTTTCCATTTAGGAGTGTTGGGAACAGCACTTGGA
GCGGTTATTGCTAGATTTATTGGGACGCTTTTTCTCTATTATAAGTTAAAAGATAAGCGACCCGATCTTCAATTTTATAA
AGAAAAATTGGACCATCAATTGATTAAATTAAGTTTACCAGCAACTGGAGAGCGTTTGTCAATGCGTTTGGGCGATTTGC
TCATCATGATGATTATTGTCAGATTAGGCGAACGTGTATTTGCAGGAAATGCAATTGGTGAAAGCATTACACAATTTAAT
TATATGCCCGTTTTCGGGATGGCAACCGTTACAGTAATTTTGGTAGCACAAGCAGCAGCTGAAAATAGTATTGAAAATGT
AAAAGCTTATATCAAAAAGACCTACTGGTTAGCGACGATTATGATGTTTGTGATTGGTTTGGCCCTTTTACTGACAGCCA
ATATTCTAAATCAATTTTTCACTACTGACAGAATTGCCATGAATGCAAGTAACACTGTTATTTTGTTTTCATTTTTAGCG
ACTTTTTTCGTCACAGGAGCAACTACTTATACAGCAGCTTTTCAGGGAATAGGAAACACAAAACTTCCTTTTTATGCCAC
AATGCTAGGGATGTTTGGCATTCGCTTGCTTTTAGGAGCATTTTTAGCCTTAGGATTAAAATTAGGGCTAGAGGGAGTTT
GGTTAGCAGTTTTACTTGATAATCTCTTTAGATTTATTTTTCTCAAAATCAAGTTTAATCGAAGCCTCACAATCAAAATT
TAA

Upstream 100 bases:

>100_bases
ATCTTGGCTTAAAATGAAAACAAATAGAGAAATATTAAAATTCGCATTTCCGGCGATTATTGAAAATTTCTTACAAATGC
TTGTAGGGGTGAGTGACACA

Downstream 100 bases:

>100_bases
AATAAAAAAATACTGACAGCTTTTCTGTCAGTAATTTTTTTATTGTTTTTTCAATAAATCGCGAATTTCTTGGAGAGTTT
CCAATTCTTCGTTTTTTTGT

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MIVAHLSLSAVAAVSLANNLITVYQAIFIALGTIVSSLFAKVLIAKKVEENPKRLINSATKLTFLIGLALGVVSVVGARP
ILYLLGARQQVLELSIIYLSLVGGLIVLLALMTTFGAFLRADGNTKTPMWASFFASLLNLILSIVFIFVFHLGVLGTALG
AVIARFIGTLFLYYKLKDKRPDLQFYKEKLDHQLIKLSLPATGERLSMRLGDLLIMMIIVRLGERVFAGNAIGESITQFN
YMPVFGMATVTVILVAQAAAENSIENVKAYIKKTYWLATIMMFVIGLALLLTANILNQFFTTDRIAMNASNTVILFSFLA
TFFVTGATTYTAAFQGIGNTKLPFYATMLGMFGIRLLLGAFLALGLKLGLEGVWLAVLLDNLFRFIFLKIKFNRSLTIKI

Sequences:

>Translated_400_residues
MIVAHLSLSAVAAVSLANNLITVYQAIFIALGTIVSSLFAKVLIAKKVEENPKRLINSATKLTFLIGLALGVVSVVGARP
ILYLLGARQQVLELSIIYLSLVGGLIVLLALMTTFGAFLRADGNTKTPMWASFFASLLNLILSIVFIFVFHLGVLGTALG
AVIARFIGTLFLYYKLKDKRPDLQFYKEKLDHQLIKLSLPATGERLSMRLGDLLIMMIIVRLGERVFAGNAIGESITQFN
YMPVFGMATVTVILVAQAAAENSIENVKAYIKKTYWLATIMMFVIGLALLLTANILNQFFTTDRIAMNASNTVILFSFLA
TFFVTGATTYTAAFQGIGNTKLPFYATMLGMFGIRLLLGAFLALGLKLGLEGVWLAVLLDNLFRFIFLKIKFNRSLTIKI
>Mature_400_residues
MIVAHLSLSAVAAVSLANNLITVYQAIFIALGTIVSSLFAKVLIAKKVEENPKRLINSATKLTFLIGLALGVVSVVGARP
ILYLLGARQQVLELSIIYLSLVGGLIVLLALMTTFGAFLRADGNTKTPMWASFFASLLNLILSIVFIFVFHLGVLGTALG
AVIARFIGTLFLYYKLKDKRPDLQFYKEKLDHQLIKLSLPATGERLSMRLGDLLIMMIIVRLGERVFAGNAIGESITQFN
YMPVFGMATVTVILVAQAAAENSIENVKAYIKKTYWLATIMMFVIGLALLLTANILNQFFTTDRIAMNASNTVILFSFLA
TFFVTGATTYTAAFQGIGNTKLPFYATMLGMFGIRLLLGAFLALGLKLGLEGVWLAVLLDNLFRFIFLKIKFNRSLTIKI

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=406, Percent_Identity=25.8620689655172, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 43837; Mature: 43837

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVAHLSLSAVAAVSLANNLITVYQAIFIALGTIVSSLFAKVLIAKKVEENPKRLINSAT
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KLTFLIGLALGVVSVVGARPILYLLGARQQVLELSIIYLSLVGGLIVLLALMTTFGAFLR
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADGNTKTPMWASFFASLLNLILSIVFIFVFHLGVLGTALGAVIARFIGTLFLYYKLKDKR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDLQFYKEKLDHQLIKLSLPATGERLSMRLGDLLIMMIIVRLGERVFAGNAIGESITQFN
CCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCC
YMPVFGMATVTVILVAQAAAENSIENVKAYIKKTYWLATIMMFVIGLALLLTANILNQFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTDRIAMNASNTVILFSFLATFFVTGATTYTAAFQGIGNTKLPFYATMLGMFGIRLLLGA
HHHHHEECCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLALGLKLGLEGVWLAVLLDNLFRFIFLKIKFNRSLTIKI
HHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEECCEEEEEC
>Mature Secondary Structure
MIVAHLSLSAVAAVSLANNLITVYQAIFIALGTIVSSLFAKVLIAKKVEENPKRLINSAT
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KLTFLIGLALGVVSVVGARPILYLLGARQQVLELSIIYLSLVGGLIVLLALMTTFGAFLR
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADGNTKTPMWASFFASLLNLILSIVFIFVFHLGVLGTALGAVIARFIGTLFLYYKLKDKR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDLQFYKEKLDHQLIKLSLPATGERLSMRLGDLLIMMIIVRLGERVFAGNAIGESITQFN
CCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCC
YMPVFGMATVTVILVAQAAAENSIENVKAYIKKTYWLATIMMFVIGLALLLTANILNQFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTDRIAMNASNTVILFSFLATFFVTGATTYTAAFQGIGNTKLPFYATMLGMFGIRLLLGA
HHHHHEECCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLALGLKLGLEGVWLAVLLDNLFRFIFLKIKFNRSLTIKI
HHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]