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The map label for this gene is yvdG

Identifier: 15674034

GI number: 15674034

Start: 2138764

End: 2139897

Strand: Reverse

Name: yvdG

Synonym: L122198

Alternate gene names: 15674034

Gene position: 2139897-2138764 (Counterclockwise)

Preceding gene: 30024072

Following gene: 15674030

Centisome position: 90.46

GC content: 37.04

Gene sequence:

>1134_bases
ATGAACTTTTCAGAAGCAATGGCTACTAAATACAAGGTTCGTGAAATTTTACACAATGGAGCCTATCACGGGGCAGCTGA
CGAACCATTGGTTTATGTTATGGATGGAATTGCGCGTTTTATTAATCAAGAAACCCTTGAGGTCGTTAATGGTGACAAGA
TAAGCAAAGTGATTGGAGAACGCATTTTCATCAATACGGGAGCAACTCCAGTGATTCCCGAAATTTCAGGAATTCAAGAA
TCCAAAAATGTAATTACATCTGAAGGAGCGATGGAACTTTCTGAACTTCCAAAGAAATTAGTTATCATCGGCGCGGGCTA
TATTGGTTTAGAATTTGCCGGAATGTTTAATAAATTTGGGTCTAAGGTCACAATTTTAGAACCTCATTCAACATTTTTAC
CCAAAGAAGACGATGATATTTCAAGGGAAATTTTTAAAGATTTAAAGGCTTCAGGAGTTGAAATTCATCTTGGGGTTAAA
GTTGAAAAAATTACTGACAGCGAAGTTTTGGCAGGAGGTCAGACCTATTCAGCTGACAAGATATTAGTGGCAACAGGTCG
CAGGCCTAATATTACTGACTTAAATTTGGAAAAAGCTGGTGTTGAACTTTCAGAAAGTGGTTATATTAAAGTTGATGATG
ATTTAAAAACAAGTACAGAAAATATCTGGGCACTTGGTGACGTTCGGGGAGGTGGACAATTCTACTATCTGTCAACAGAT
GATTTTCGGATTGTCAATAATCAATTGTTTGGTGATCACTCGCGTAAATTAAGTGACAGAACACTCGTGCCCTATTCTGT
TTTTATTAGTCCAACATTATCTCGAATTGGCTTGGATGAAAAACAAGCGAAAAAAGCTGGGGTTAATTATCATTTATTTA
AGATGGCTGCGGCACCAATTGTTAAGTCTAAAGTTGTTCAAGATACTCGCGGAATTCTTAAAGCTCTTGTTGACCCAAAA
ACAGATGAAATTCTCGGTGCAACTTTATATCATGAAGATTCTCATGAGGTCATCAATCTTGTAAGTTTGGCTATGAAAAT
GCATACGCCCTATCAAATTTTACGCGACCAAATTTTCACTCATCCAACAATGGGCGAAGGTCTGAATGATTTATTTCAAA
ATGAAGTGAAATAA

Upstream 100 bases:

>100_bases
CTCTGATTATTGAACGTGACCAGGCGATGTACGGCGGAACTTGTCCCAATGTTGGCTGTGCACCTTCTAAAACTCTAATT
GTTGCCGGACAAAAAAAAAT

Downstream 100 bases:

>100_bases
AAGTTACTGACAGCTTTCTTTTATGAGTGAGTATCGCACAAAAAATTTCTGTCAGTAAAAAAAACTCGTCATTGACGAGT
TATTTAATTATTTGAATTGG

Product: pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MNFSEAMATKYKVREILHNGAYHGAADEPLVYVMDGIARFINQETLEVVNGDKISKVIGERIFINTGATPVIPEISGIQE
SKNVITSEGAMELSELPKKLVIIGAGYIGLEFAGMFNKFGSKVTILEPHSTFLPKEDDDISREIFKDLKASGVEIHLGVK
VEKITDSEVLAGGQTYSADKILVATGRRPNITDLNLEKAGVELSESGYIKVDDDLKTSTENIWALGDVRGGGQFYYLSTD
DFRIVNNQLFGDHSRKLSDRTLVPYSVFISPTLSRIGLDEKQAKKAGVNYHLFKMAAAPIVKSKVVQDTRGILKALVDPK
TDEILGATLYHEDSHEVINLVSLAMKMHTPYQILRDQIFTHPTMGEGLNDLFQNEVK

Sequences:

>Translated_377_residues
MNFSEAMATKYKVREILHNGAYHGAADEPLVYVMDGIARFINQETLEVVNGDKISKVIGERIFINTGATPVIPEISGIQE
SKNVITSEGAMELSELPKKLVIIGAGYIGLEFAGMFNKFGSKVTILEPHSTFLPKEDDDISREIFKDLKASGVEIHLGVK
VEKITDSEVLAGGQTYSADKILVATGRRPNITDLNLEKAGVELSESGYIKVDDDLKTSTENIWALGDVRGGGQFYYLSTD
DFRIVNNQLFGDHSRKLSDRTLVPYSVFISPTLSRIGLDEKQAKKAGVNYHLFKMAAAPIVKSKVVQDTRGILKALVDPK
TDEILGATLYHEDSHEVINLVSLAMKMHTPYQILRDQIFTHPTMGEGLNDLFQNEVK
>Mature_377_residues
MNFSEAMATKYKVREILHNGAYHGAADEPLVYVMDGIARFINQETLEVVNGDKISKVIGERIFINTGATPVIPEISGIQE
SKNVITSEGAMELSELPKKLVIIGAGYIGLEFAGMFNKFGSKVTILEPHSTFLPKEDDDISREIFKDLKASGVEIHLGVK
VEKITDSEVLAGGQTYSADKILVATGRRPNITDLNLEKAGVELSESGYIKVDDDLKTSTENIWALGDVRGGGQFYYLSTD
DFRIVNNQLFGDHSRKLSDRTLVPYSVFISPTLSRIGLDEKQAKKAGVNYHLFKMAAAPIVKSKVVQDTRGILKALVDPK
TDEILGATLYHEDSHEVINLVSLAMKMHTPYQILRDQIFTHPTMGEGLNDLFQNEVK

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=389, Percent_Identity=28.7917737789203, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI50301238, Length=374, Percent_Identity=27.807486631016, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI22035672, Length=349, Percent_Identity=28.3667621776504, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI291045266, Length=376, Percent_Identity=25.531914893617, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI33519430, Length=379, Percent_Identity=25.065963060686, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI33519428, Length=379, Percent_Identity=25.065963060686, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI33519426, Length=379, Percent_Identity=25.065963060686, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI148277065, Length=379, Percent_Identity=25.065963060686, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI148277071, Length=379, Percent_Identity=25.065963060686, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI87081717, Length=375, Percent_Identity=48, Blast_Score=331, Evalue=6e-92,
Organism=Escherichia coli, GI1786307, Length=362, Percent_Identity=27.3480662983425, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789915, Length=374, Percent_Identity=27.807486631016, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87082354, Length=358, Percent_Identity=27.0949720670391, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32565766, Length=352, Percent_Identity=26.9886363636364, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71983419, Length=364, Percent_Identity=28.2967032967033, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71983429, Length=364, Percent_Identity=28.2967032967033, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17557007, Length=367, Percent_Identity=25.8855585831063, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71982272, Length=380, Percent_Identity=23.9473684210526, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321091, Length=325, Percent_Identity=30.1538461538462, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6325166, Length=364, Percent_Identity=27.4725274725275, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6325240, Length=370, Percent_Identity=24.3243243243243, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21358499, Length=350, Percent_Identity=31.1428571428571, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24640553, Length=358, Percent_Identity=25.9776536312849, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24640549, Length=358, Percent_Identity=25.9776536312849, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24640551, Length=361, Percent_Identity=26.0387811634349, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17737741, Length=366, Percent_Identity=27.5956284153005, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 41664; Mature: 41664

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSEAMATKYKVREILHNGAYHGAADEPLVYVMDGIARFINQETLEVVNGDKISKVIGE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCHHHHHHCC
RIFINTGATPVIPEISGIQESKNVITSEGAMELSELPKKLVIIGAGYIGLEFAGMFNKFG
EEEEECCCCCCCCCCCCCHHHHCEECCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHC
SKVTILEPHSTFLPKEDDDISREIFKDLKASGVEIHLGVKVEKITDSEVLAGGQTYSADK
CEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEEECCCHHHCCCCCCCCCE
ILVATGRRPNITDLNLEKAGVELSESGYIKVDDDLKTSTENIWALGDVRGGGQFYYLSTD
EEEEECCCCCCCCCCHHHCCCEECCCCCEEECCCCCCCCCCEEEEEEECCCCEEEEEECC
DFRIVNNQLFGDHSRKLSDRTLVPYSVFISPTLSRIGLDEKQAKKAGVNYHLFKMAAAPI
CEEEECCCCCCCHHHCCCCCEECEEEEEECCHHHHCCCCHHHHHHCCCCEEEHHHHHHHH
VKSKVVQDTRGILKALVDPKTDEILGATLYHEDSHEVINLVSLAMKMHTPYQILRDQIFT
HHHHHHHHHHHHHHHHCCCCCHHHHEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHC
HPTMGEGLNDLFQNEVK
CCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNFSEAMATKYKVREILHNGAYHGAADEPLVYVMDGIARFINQETLEVVNGDKISKVIGE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCHHHHHHCC
RIFINTGATPVIPEISGIQESKNVITSEGAMELSELPKKLVIIGAGYIGLEFAGMFNKFG
EEEEECCCCCCCCCCCCCHHHHCEECCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHC
SKVTILEPHSTFLPKEDDDISREIFKDLKASGVEIHLGVKVEKITDSEVLAGGQTYSADK
CEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEEECCCHHHCCCCCCCCCE
ILVATGRRPNITDLNLEKAGVELSESGYIKVDDDLKTSTENIWALGDVRGGGQFYYLSTD
EEEEECCCCCCCCCCHHHCCCEECCCCCEEECCCCCCCCCCEEEEEEECCCCEEEEEECC
DFRIVNNQLFGDHSRKLSDRTLVPYSVFISPTLSRIGLDEKQAKKAGVNYHLFKMAAAPI
CEEEECCCCCCCHHHCCCCCEECEEEEEECCHHHHCCCCHHHHHHCCCCEEEHHHHHHHH
VKSKVVQDTRGILKALVDPKTDEILGATLYHEDSHEVINLVSLAMKMHTPYQILRDQIFT
HHHHHHHHHHHHHHHHCCCCCHHHHEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHC
HPTMGEGLNDLFQNEVK
CCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]