Click here to switch to the map view.

The map label for this gene is yvdD

Identifier: 15674030

GI number: 15674030

Start: 2133640

End: 2134509

Strand: Reverse

Name: yvdD

Synonym: L117074

Alternate gene names: 15674030

Gene position: 2134509-2133640 (Counterclockwise)

Preceding gene: 15674034

Following gene: 15674028

Centisome position: 90.23

GC content: 40.0

Gene sequence:

>870_bases
ATGGATGTTACATGGACAGTGAAATATATCACTGAATTTGTCGGAACTGCGCTACTCATCATCATGGGTAATGGTGCGGT
TGCCAACGTTGAACTTAAAGGTACAAAAGCTCACGCACAATCTTGGATGATTATTGGTTGGGGTTATGGACTTGGTGTAA
TGCTACCAGCAGTTGCTTTCGGTAATATTACTTCACAAATTAATCCAGCTTTCACACTTGGACTTGCAGCCTCAGGACTT
TTTCCTTGGGCACATGTTGCTCAATATATTATTGCGCAAGTTTTAGGTGCGATGTTTGGACAATTATTGATTGTTATGGT
TTATCGCCCATACTATCTTAAAACACAAAATCCAAATGCTATTCTTGGAACTTTCTCAACAATCGATAATGTTGATGACA
ATGATAAAAAAACTCGTTTGGGAGCCACAATTAATGGTTTCTTGAATGAATTTGTTGGATCATTCGTCTTGTTCTTCGGA
GCAGTTGCTGCGACAAATATCTTCTTTGGTAGTCAATCAATTACTTGGATGACAAACTACTTGAAAGGTCAAGGAGCAGA
TGTTTCTTCATCAGACATTATGAATCAGATTTGGGTTCAAGCCTCAGGAGCTTCAGCTTCTAAAATGGTTGCTCACTTAT
TCTTAGGATTCCTTGTTATGGGACTTGTAGTCGCTCTTGGCGGTCCTACAGGACCTGGTTTGAATCCAGCGCGTGACTTT
GGTCCACGTTTGGTTCACAGCCTCTTACCAAAATCAGTTTTGGGTGAAGCAAAAGGTTCTTCTAAATGGTGGTATGCATG
GGTTCCAGTTTTGGCACCAATTCTTGCATCACTTGCAGCCGTAGCTCTATTTAAAATGATTTATCTTTAA

Upstream 100 bases:

>100_bases
AGGGTCTAATTTCCAATGAATATTTGAAGCAAGCGCGCTTTTCTGATATAATAGCTGAGGTTATTATATTAAAATCAAAT
TTTGGAGGGTTCCATAAAAA

Downstream 100 bases:

>100_bases
AAAATAAAAAAAATACTGACAGAATTTCTGTCAGTATTTTTTTTATTTAAGCACAAGCGCAATTACTAACCCAAAGAGAT
TCCAAAGAAGATGGACACTC

Product: transporter

Products: glycerol [Cytoplasm] [C]

Alternate protein names: Aquaglyceroporin; Glyceroaquaporin

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDVTWTVKYITEFVGTALLIIMGNGAVANVELKGTKAHAQSWMIIGWGYGLGVMLPAVAFGNITSQINPAFTLGLAASGL
FPWAHVAQYIIAQVLGAMFGQLLIVMVYRPYYLKTQNPNAILGTFSTIDNVDDNDKKTRLGATINGFLNEFVGSFVLFFG
AVAATNIFFGSQSITWMTNYLKGQGADVSSSDIMNQIWVQASGASASKMVAHLFLGFLVMGLVVALGGPTGPGLNPARDF
GPRLVHSLLPKSVLGEAKGSSKWWYAWVPVLAPILASLAAVALFKMIYL

Sequences:

>Translated_289_residues
MDVTWTVKYITEFVGTALLIIMGNGAVANVELKGTKAHAQSWMIIGWGYGLGVMLPAVAFGNITSQINPAFTLGLAASGL
FPWAHVAQYIIAQVLGAMFGQLLIVMVYRPYYLKTQNPNAILGTFSTIDNVDDNDKKTRLGATINGFLNEFVGSFVLFFG
AVAATNIFFGSQSITWMTNYLKGQGADVSSSDIMNQIWVQASGASASKMVAHLFLGFLVMGLVVALGGPTGPGLNPARDF
GPRLVHSLLPKSVLGEAKGSSKWWYAWVPVLAPILASLAAVALFKMIYL
>Mature_289_residues
MDVTWTVKYITEFVGTALLIIMGNGAVANVELKGTKAHAQSWMIIGWGYGLGVMLPAVAFGNITSQINPAFTLGLAASGL
FPWAHVAQYIIAQVLGAMFGQLLIVMVYRPYYLKTQNPNAILGTFSTIDNVDDNDKKTRLGATINGFLNEFVGSFVLFFG
AVAATNIFFGSQSITWMTNYLKGQGADVSSSDIMNQIWVQASGASASKMVAHLFLGFLVMGLVVALGGPTGPGLNPARDF
GPRLVHSLLPKSVLGEAKGSSKWWYAWVPVLAPILASLAAVALFKMIYL

Specific function: Mixed channel protein that transports both water and glycerol

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family

Homologues:

Organism=Saccharomyces cerevisiae, GI6321054, Length=247, Percent_Identity=28.7449392712551, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLA_LACLA (Q9CE02)

Other databases:

- EMBL:   AE005176
- PIR:   H86880
- RefSeq:   NP_268205.1
- ProteinModelPortal:   Q9CE02
- SMR:   Q9CE02
- GeneID:   1115724
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L117074
- NMPDR:   fig|272623.1.peg.2102
- HOGENOM:   HBG705794
- OMA:   LGPRILH
- ProtClustDB:   CLSK698087
- BioCyc:   LLAC272623:L117074-MONOMER
- InterPro:   IPR000425
- InterPro:   IPR022357
- PANTHER:   PTHR19139
- PRINTS:   PR00783

Pfam domain/function: PF00230 MIP

EC number: NA

Molecular weight: Translated: 30949; Mature: 30949

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe1594e8)-; HASH(0xb9ae900)-; HASH(0xf8c11c4)-; HASH(0x10090b30)-; HASH(0xc557694)-; HASH(0xfab34a0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVTWTVKYITEFVGTALLIIMGNGAVANVELKGTKAHAQSWMIIGWGYGLGVMLPAVAF
CCCEEHHHHHHHHHHHEEEEEECCCCEEEEEECCCHHHHCEEEEEEECCCHHHHHHHHHH
GNITSQINPAFTLGLAASGLFPWAHVAQYIIAQVLGAMFGQLLIVMVYRPYYLKTQNPNA
CCHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCE
ILGTFSTIDNVDDNDKKTRLGATINGFLNEFVGSFVLFFGAVAATNIFFGSQSITWMTNY
EEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LKGQGADVSSSDIMNQIWVQASGASASKMVAHLFLGFLVMGLVVALGGPTGPGLNPARDF
HCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
GPRLVHSLLPKSVLGEAKGSSKWWYAWVPVLAPILASLAAVALFKMIYL
HHHHHHHHCCHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MDVTWTVKYITEFVGTALLIIMGNGAVANVELKGTKAHAQSWMIIGWGYGLGVMLPAVAF
CCCEEHHHHHHHHHHHEEEEEECCCCEEEEEECCCHHHHCEEEEEEECCCHHHHHHHHHH
GNITSQINPAFTLGLAASGLFPWAHVAQYIIAQVLGAMFGQLLIVMVYRPYYLKTQNPNA
CCHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCE
ILGTFSTIDNVDDNDKKTRLGATINGFLNEFVGSFVLFFGAVAATNIFFGSQSITWMTNY
EEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LKGQGADVSSSDIMNQIWVQASGASASKMVAHLFLGFLVMGLVVALGGPTGPGLNPARDF
HCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
GPRLVHSLLPKSVLGEAKGSSKWWYAWVPVLAPILASLAAVALFKMIYL
HHHHHHHHCCHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glycerol [Periplasm] [C]

Specific reaction: glycerol [Periplasm] = glycerol [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11337471