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The map label for this gene is argS

Identifier: 15674020

GI number: 15674020

Start: 2115841

End: 2117535

Strand: Reverse

Name: argS

Synonym: L0344

Alternate gene names: 15674020

Gene position: 2117535-2115841 (Counterclockwise)

Preceding gene: 161723236

Following gene: 15674019

Centisome position: 89.51

GC content: 36.99

Gene sequence:

>1695_bases
ATGGATGAAAAACAATTAGTAAGCCAAGCACTGTCTGCTGCAATCGATGGTGTTCTTGGAGTAGAACAAATCGCGGCTAT
TATCGAAAAACCTAAATCATCAGATTTAGGAGATTTAGCATTCCCAGCTTTTCAATTGGCCAAAACTCTCCGAAAATCTC
CACAAATCATTGCTGGAGAAATTGCTGAGAAGATAGATACAAAAGGCTTTGAGAAAGTTATCGCAGTAGGACCATATGTT
AACTTTTTCCTTGATAAAAATGCAACTGCCTCAGAAGTAATTCGAGAAGTTTTGACTGAAGGTGAACATTACGGTGATGC
AAATATTGGTCAAGGAGGAAATGTTCCGATTGACATGTCTGCGCCAAATATTGCTAAACCTTTTTCAATTGGGCATTTAC
GTTCAACTGTTATCGGGGATTCAATCGCCAAAATTTATGAAAAATTGGGTTATCAGCCAATCAAAATCAATCACTTGGGC
GACTGGGGTAAACAATTTGGTCTTTTGATTACAGCTTACAAGAAATATGGTGATGAAGCTACAATTACAGCTAATCCGAT
TGATGAACTCTTGAAACTTTATGTCAAAATCAATGCTGAAGCTAAAGAAGATCCAGAAGTCGATGAAGAAGGACGTCAAT
GGTTCCTTAAAATGGAACAAGGCGATGAGGAAGCACTTCGCATTTGGAAATGGTTCTCAGATGTTTCTTTGATTGAATTT
AACCGTATTTACGGAAAACTTGGTGTAAGTTTTGACCACTTCATGGGTGAAAGTTTCTATAGTGATAAAATGGACGCCAT
TGTTGAAGATTTAGAAAGTAAAAATCTTTTACACGAATCAAAAGGTGCTTTGATTGTTGACCTTGAAAAATATAACCTCA
ATCCAGCTTTGATTAAGAAAACAGATGGTGCAACACTCTATATTACACGTGACCTTGCAACAGCAGCTTACCGTAAAAAA
ACTTTCAATTTCGTGAAATCTCTTTATGTTGTTGGTGGCGAGCAAACCAATCACTTTAAACAATTAAAAGCAGTTTTGAA
AGAAGCTGGTTATGATTGGTCTGACGATATGGTGCACGTTCCATTTGGTATGGTAACTCAAGGTGGGAAAAAATTCTCAA
CTCGTAAAGGGCATGTCGTGAAATTGGAAATGGCACTTGACGAAGCAGTTGATCGTGCTGAAAAACAAATTGAAGCCAAA
AATCCTAATTTGGAAAATAAAGAAGAAGTTGCCAAACAAGTTGGGGTTGGTGCTGTTAAATTTTATGACTTAAAAACTGA
TAGAAATAACGGTTATGACTTTGACTTGGACGAAATGGTTTCATTTGAAGGGGAAACAGGCCCTTATGTTCAATATGCAC
ATGCTCGTATTCAATCAATTTTACGTAAAGCAAACCGTAAGGTAGATATTAATAATATTTCTCTCGCAGTTTCTGACGCT
GAAGCTTGGGAAATTGTTAAAGCATTAAAAGAATTCCCAAATGTTGTTAAACGTGCTGCAGATAATTATGAACCATCTGT
TATTGCTAAATATGCAATTTCGCTTGCGCAAGCTTTTAACAAATATTATGCTCATGTTCGCATTTTAGAAGATGATGCTC
AATTGGATGGCCGTTTGGCTTTGATTAGCGCTACTTCAATCGTCTTGAAAGAAGCATTGCGTCTTCTTGGGGTTGCTGCA
CCTGAAAATATGTAA

Upstream 100 bases:

>100_bases
TTTAATAATTTCTAATCTTTTATCTCTTTTCATAGCATAATTATACCATATAATGGACTATATATTGACAAAATTAGTGT
TTTTTCTGTATAATTAATGA

Downstream 100 bases:

>100_bases
AAAATAAATTTTTCACTTAATCTCTTATCAAAAAGATTTAATTCTTTAGGATAAGAGATTTTTTTGTTGCCTTTTTAAAA
TACTTTTGTAAAATAAGCTT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MDEKQLVSQALSAAIDGVLGVEQIAAIIEKPKSSDLGDLAFPAFQLAKTLRKSPQIIAGEIAEKIDTKGFEKVIAVGPYV
NFFLDKNATASEVIREVLTEGEHYGDANIGQGGNVPIDMSAPNIAKPFSIGHLRSTVIGDSIAKIYEKLGYQPIKINHLG
DWGKQFGLLITAYKKYGDEATITANPIDELLKLYVKINAEAKEDPEVDEEGRQWFLKMEQGDEEALRIWKWFSDVSLIEF
NRIYGKLGVSFDHFMGESFYSDKMDAIVEDLESKNLLHESKGALIVDLEKYNLNPALIKKTDGATLYITRDLATAAYRKK
TFNFVKSLYVVGGEQTNHFKQLKAVLKEAGYDWSDDMVHVPFGMVTQGGKKFSTRKGHVVKLEMALDEAVDRAEKQIEAK
NPNLENKEEVAKQVGVGAVKFYDLKTDRNNGYDFDLDEMVSFEGETGPYVQYAHARIQSILRKANRKVDINNISLAVSDA
EAWEIVKALKEFPNVVKRAADNYEPSVIAKYAISLAQAFNKYYAHVRILEDDAQLDGRLALISATSIVLKEALRLLGVAA
PENM

Sequences:

>Translated_564_residues
MDEKQLVSQALSAAIDGVLGVEQIAAIIEKPKSSDLGDLAFPAFQLAKTLRKSPQIIAGEIAEKIDTKGFEKVIAVGPYV
NFFLDKNATASEVIREVLTEGEHYGDANIGQGGNVPIDMSAPNIAKPFSIGHLRSTVIGDSIAKIYEKLGYQPIKINHLG
DWGKQFGLLITAYKKYGDEATITANPIDELLKLYVKINAEAKEDPEVDEEGRQWFLKMEQGDEEALRIWKWFSDVSLIEF
NRIYGKLGVSFDHFMGESFYSDKMDAIVEDLESKNLLHESKGALIVDLEKYNLNPALIKKTDGATLYITRDLATAAYRKK
TFNFVKSLYVVGGEQTNHFKQLKAVLKEAGYDWSDDMVHVPFGMVTQGGKKFSTRKGHVVKLEMALDEAVDRAEKQIEAK
NPNLENKEEVAKQVGVGAVKFYDLKTDRNNGYDFDLDEMVSFEGETGPYVQYAHARIQSILRKANRKVDINNISLAVSDA
EAWEIVKALKEFPNVVKRAADNYEPSVIAKYAISLAQAFNKYYAHVRILEDDAQLDGRLALISATSIVLKEALRLLGVAA
PENM
>Mature_564_residues
MDEKQLVSQALSAAIDGVLGVEQIAAIIEKPKSSDLGDLAFPAFQLAKTLRKSPQIIAGEIAEKIDTKGFEKVIAVGPYV
NFFLDKNATASEVIREVLTEGEHYGDANIGQGGNVPIDMSAPNIAKPFSIGHLRSTVIGDSIAKIYEKLGYQPIKINHLG
DWGKQFGLLITAYKKYGDEATITANPIDELLKLYVKINAEAKEDPEVDEEGRQWFLKMEQGDEEALRIWKWFSDVSLIEF
NRIYGKLGVSFDHFMGESFYSDKMDAIVEDLESKNLLHESKGALIVDLEKYNLNPALIKKTDGATLYITRDLATAAYRKK
TFNFVKSLYVVGGEQTNHFKQLKAVLKEAGYDWSDDMVHVPFGMVTQGGKKFSTRKGHVVKLEMALDEAVDRAEKQIEAK
NPNLENKEEVAKQVGVGAVKFYDLKTDRNNGYDFDLDEMVSFEGETGPYVQYAHARIQSILRKANRKVDINNISLAVSDA
EAWEIVKALKEFPNVVKRAADNYEPSVIAKYAISLAQAFNKYYAHVRILEDDAQLDGRLALISATSIVLKEALRLLGVAA
PENM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=528, Percent_Identity=35.4166666666667, Blast_Score=315, Evalue=7e-86,
Organism=Homo sapiens, GI15149476, Length=548, Percent_Identity=31.7518248175182, Blast_Score=238, Evalue=1e-62,
Organism=Escherichia coli, GI1788184, Length=540, Percent_Identity=35.9259259259259, Blast_Score=293, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI71985061, Length=548, Percent_Identity=31.021897810219, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI71985068, Length=507, Percent_Identity=31.5581854043393, Blast_Score=205, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17532153, Length=490, Percent_Identity=26.734693877551, Blast_Score=162, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6320548, Length=581, Percent_Identity=37.8657487091222, Blast_Score=379, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6321883, Length=578, Percent_Identity=36.159169550173, Blast_Score=367, Evalue=1e-102,
Organism=Drosophila melanogaster, GI18859963, Length=541, Percent_Identity=30.6839186691312, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI28571570, Length=471, Percent_Identity=31.8471337579618, Blast_Score=218, Evalue=8e-57,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_LACLA (Q9CE12)

Other databases:

- EMBL:   AE005176
- PIR:   F86879
- RefSeq:   NP_268195.1
- ProteinModelPortal:   Q9CE12
- SMR:   Q9CE12
- GeneID:   1115714
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0344
- NMPDR:   fig|272623.1.peg.2092
- HOGENOM:   HBG695395
- OMA:   AYKKWGN
- ProtClustDB:   PRK01611
- BioCyc:   LLAC272623:L0344-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 62819; Mature: 62819

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEKQLVSQALSAAIDGVLGVEQIAAIIEKPKSSDLGDLAFPAFQLAKTLRKSPQIIAGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
IAEKIDTKGFEKVIAVGPYVNFFLDKNATASEVIREVLTEGEHYGDANIGQGGNVPIDMS
HHHHHCCCHHHHHHEECCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECC
APNIAKPFSIGHLRSTVIGDSIAKIYEKLGYQPIKINHLGDWGKQFGLLITAYKKYGDEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHEEHHHCCCCC
TITANPIDELLKLYVKINAEAKEDPEVDEEGRQWFLKMEQGDEEALRIWKWFSDVSLIEF
EEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEECCCCHHHHHHHHHHCCCHHHHH
NRIYGKLGVSFDHFMGESFYSDKMDAIVEDLESKNLLHESKGALIVDLEKYNLNPALIKK
HHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHEEEE
TDGATLYITRDLATAAYRKKTFNFVKSLYVVGGEQTNHFKQLKAVLKEAGYDWSDDMVHV
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEC
PFGMVTQGGKKFSTRKGHVVKLEMALDEAVDRAEKQIEAKNPNLENKEEVAKQVGVGAVK
CCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEE
FYDLKTDRNNGYDFDLDEMVSFEGETGPYVQYAHARIQSILRKANRKVDINNISLAVSDA
EEEEECCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCEEEEECCH
EAWEIVKALKEFPNVVKRAADNYEPSVIAKYAISLAQAFNKYYAHVRILEDDAQLDGRLA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEE
LISATSIVLKEALRLLGVAAPENM
EEHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDEKQLVSQALSAAIDGVLGVEQIAAIIEKPKSSDLGDLAFPAFQLAKTLRKSPQIIAGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
IAEKIDTKGFEKVIAVGPYVNFFLDKNATASEVIREVLTEGEHYGDANIGQGGNVPIDMS
HHHHHCCCHHHHHHEECCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECC
APNIAKPFSIGHLRSTVIGDSIAKIYEKLGYQPIKINHLGDWGKQFGLLITAYKKYGDEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHEEHHHCCCCC
TITANPIDELLKLYVKINAEAKEDPEVDEEGRQWFLKMEQGDEEALRIWKWFSDVSLIEF
EEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEECCCCHHHHHHHHHHCCCHHHHH
NRIYGKLGVSFDHFMGESFYSDKMDAIVEDLESKNLLHESKGALIVDLEKYNLNPALIKK
HHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHEEEE
TDGATLYITRDLATAAYRKKTFNFVKSLYVVGGEQTNHFKQLKAVLKEAGYDWSDDMVHV
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEC
PFGMVTQGGKKFSTRKGHVVKLEMALDEAVDRAEKQIEAKNPNLENKEEVAKQVGVGAVK
CCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEE
FYDLKTDRNNGYDFDLDEMVSFEGETGPYVQYAHARIQSILRKANRKVDINNISLAVSDA
EEEEECCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCEEEEECCH
EAWEIVKALKEFPNVVKRAADNYEPSVIAKYAISLAQAFNKYYAHVRILEDDAQLDGRLA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEE
LISATSIVLKEALRLLGVAAPENM
EEHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471