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The map label for this gene is thgA

Identifier: 15673963

GI number: 15673963

Start: 2058181

End: 2058642

Strand: Reverse

Name: thgA

Synonym: L0026

Alternate gene names: 15673963

Gene position: 2058642-2058181 (Counterclockwise)

Preceding gene: 30024071

Following gene: 30024070

Centisome position: 87.02

GC content: 34.42

Gene sequence:

>462_bases
ATGTTTTCAGAAATTGGGGAAAATTGTTTTATTCAACCCCCTTTTTATGCTAATTTTGGCGGAAAAAATGTTCATTTTGG
GACAGAGATTTATGCTAATTTTAATCTAACATTGGTTGACGATACAGATATTTTTGTAGGAAATCATGTCATGTTTGGAC
CAAATGTTACGATTGACACGGCGACACATCCTGTCTCGCCTGACTTACGTAAACGAGGGGCTCAATATAATAAAAAAGTT
TACATTGAAGAAAACGTTTGGCTAGGTGCTGGTGTAATTGTTTTACCTGGTGTTAGAATTGGAAAAAATAGTGTGATTGG
CGCAGGGAGTCTTGTAACTAAAGACATTCCAGATAATGTGGTTGCTTTTGGAACTCCTTGTATGGTTAAAAGAAAAATTA
ATGATTCTGACTTTAAAACTTATGATCATGGAAAAAAGATTGATTTAGATGAGTTCATCTGA

Upstream 100 bases:

>100_bases
AAAAATTATGGAAAGAGCAACAAGAAGCTTTAGTTTTACTGGAAAAGTTTAATCAAACTTCAGTGACTCAGCCAGAGCAA
CAAATGGAACTTCTAAAAAA

Downstream 100 bases:

>100_bases
AAGGAATGGCTATGATGACAATGATTGATGTACTAGAGCGTAAAGATTGGGAAAATCCAGTAGTTTCAAATTGGAATAGG
TTGCCAATGCATACACCTAT

Product: thiogalactoside acetyltransferase

Products: NA

Alternate protein names: GAT; Thiogalactoside acetyltransferase [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MFSEIGENCFIQPPFYANFGGKNVHFGTEIYANFNLTLVDDTDIFVGNHVMFGPNVTIDTATHPVSPDLRKRGAQYNKKV
YIEENVWLGAGVIVLPGVRIGKNSVIGAGSLVTKDIPDNVVAFGTPCMVKRKINDSDFKTYDHGKKIDLDEFI

Sequences:

>Translated_153_residues
MFSEIGENCFIQPPFYANFGGKNVHFGTEIYANFNLTLVDDTDIFVGNHVMFGPNVTIDTATHPVSPDLRKRGAQYNKKV
YIEENVWLGAGVIVLPGVRIGKNSVIGAGSLVTKDIPDNVVAFGTPCMVKRKINDSDFKTYDHGKKIDLDEFI
>Mature_153_residues
MFSEIGENCFIQPPFYANFGGKNVHFGTEIYANFNLTLVDDTDIFVGNHVMFGPNVTIDTATHPVSPDLRKRGAQYNKKV
YIEENVWLGAGVIVLPGVRIGKNSVIGAGSLVTKDIPDNVVAFGTPCMVKRKINDSDFKTYDHGKKIDLDEFI

Specific function: May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=148, Percent_Identity=51.3513513513513, Blast_Score=156, Evalue=5e-40,
Organism=Escherichia coli, GI1786664, Length=133, Percent_Identity=40.6015037593985, Blast_Score=110, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322243, Length=145, Percent_Identity=46.2068965517241, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.18 [H]

Molecular weight: Translated: 16928; Mature: 16928

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSEIGENCFIQPPFYANFGGKNVHFGTEIYANFNLTLVDDTDIFVGNHVMFGPNVTIDT
CCCCCCCCEEECCCEEECCCCCEEEECEEEEEEEEEEEEECCCEEECCEEEECCCEEEEC
ATHPVSPDLRKRGAQYNKKVYIEENVWLGAGVIVLPGVRIGKNSVIGAGSLVTKDIPDNV
CCCCCCHHHHHCCCCCCCEEEEECCEEECCCEEEECCEEECCCCEEECCCEEECCCCCCE
VAFGTPCMVKRKINDSDFKTYDHGKKIDLDEFI
EEECCCEEEEEECCCCCCEECCCCCCCCHHHCC
>Mature Secondary Structure
MFSEIGENCFIQPPFYANFGGKNVHFGTEIYANFNLTLVDDTDIFVGNHVMFGPNVTIDT
CCCCCCCCEEECCCEEECCCCCEEEECEEEEEEEEEEEEECCCEEECCEEEECCCEEEEC
ATHPVSPDLRKRGAQYNKKVYIEENVWLGAGVIVLPGVRIGKNSVIGAGSLVTKDIPDNV
CCCCCCHHHHHCCCCCCCEEEEECCEEECCCEEEECCEEECCCCEEECCCEEECCCCCCE
VAFGTPCMVKRKINDSDFKTYDHGKKIDLDEFI
EEECCCEEEEEECCCCCCEECCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]