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The map label for this gene is yrbC

Identifier: 15673645

GI number: 15673645

Start: 1712667

End: 1713626

Strand: Direct

Name: yrbC

Synonym: L112353

Alternate gene names: 15673645

Gene position: 1712667-1713626 (Clockwise)

Preceding gene: 15673643

Following gene: 15673665

Centisome position: 72.4

GC content: 32.29

Gene sequence:

>960_bases
ATGTCCCTCAAAAATTTTTTAGAACTCGTCGAAATAAAAACTAAAATCGCCAGTATTTTCCCTTACATTATTGGTTTACT
TTTTAGTTTAAGCTATTTTAAAATGATAAATATTGGCCTATCTCTCTTATTTTTAATAGCAATGCTCCTTTTTGATATGA
CCGTAACTGCTATTAACAATTATCAAGATTTCAAAAAAGCCAAAGATGAAGATTATAAAAAGCAAGAAAATATCATTGGT
CAAGCCAATCTTTCCACCCGATTGGTAGCTTCTATTATCTTGTTTATGCTTATTTTGAGCCTTTTTTTAGGATTTCTCCT
CGCTTATTTTGTTGGCTGGCTTTTCTTTATTCTTGGTGGAATCGTCTTCTTTATTGGCGTTTTCTATACTTACGGTCCTA
TTCCACTTTCACGTATGCCTTTAGGAGAAATTTTTTCTGGTGGGACAATGGGCTTTGGAATTTTTGCAATGATCATCTTA
ATCAACAGCGCTCAATCACCTATTTTTAACCTAAATCTTGATTTCACAAACGACTCTTTTAGCTTTACTGGTAGTATTTT
TGCAGCCATCGCCATGATAATTGCAAGTTTACCACTCATTTTTACCATTGCAAACATCATGCTGGCCAATAATTTACGTG
ATTTAGATAGCGATATAAAAAATCATCGTTACACATTAGTTTATTATATCGGTCGTCCAAACGGAATCAAACTTTTTCAA
CTTTTGATGTATTCTTCCTATTTAGCTATTATTATTGGATTTATCTTTAGAATATTTGAATGGCCAACTTTACTTAGTTT
ACTCACTTTTCCAATTATCAGAAAGAATCTAAAATCTCATGCTAGTCAAGTTCCAAGTCCTCGCAGCTTTGTTTATTCAC
TGAGAAATATGGTTCTATTTAACAGCGCTTATGCTGTGAGTCTGTTTTTATCAATCCTTTGGCAATATTTAAGCAAATAA

Upstream 100 bases:

>100_bases
ATATGATTAAAAAATAGAGAATTATTTTCTCAAAAAATAAATAAGTAAAAGCCGTAAAATAACGGCTGTTTTTATTCAAA
TTATATTTTCAGGAGTAATT

Downstream 100 bases:

>100_bases
AAAAAGTGATAGAATATCACTTTTTTATTTTTCATTTAAAACCTGACGAAGCTGTTCTCTAGCAATCACTTCATCTTCTC
GTCTAATCAAAAAGGTCAAA

Product: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSLKNFLELVEIKTKIASIFPYIIGLLFSLSYFKMINIGLSLLFLIAMLLFDMTVTAINNYQDFKKAKDEDYKKQENIIG
QANLSTRLVASIILFMLILSLFLGFLLAYFVGWLFFILGGIVFFIGVFYTYGPIPLSRMPLGEIFSGGTMGFGIFAMIIL
INSAQSPIFNLNLDFTNDSFSFTGSIFAAIAMIIASLPLIFTIANIMLANNLRDLDSDIKNHRYTLVYYIGRPNGIKLFQ
LLMYSSYLAIIIGFIFRIFEWPTLLSLLTFPIIRKNLKSHASQVPSPRSFVYSLRNMVLFNSAYAVSLFLSILWQYLSK

Sequences:

>Translated_319_residues
MSLKNFLELVEIKTKIASIFPYIIGLLFSLSYFKMINIGLSLLFLIAMLLFDMTVTAINNYQDFKKAKDEDYKKQENIIG
QANLSTRLVASIILFMLILSLFLGFLLAYFVGWLFFILGGIVFFIGVFYTYGPIPLSRMPLGEIFSGGTMGFGIFAMIIL
INSAQSPIFNLNLDFTNDSFSFTGSIFAAIAMIIASLPLIFTIANIMLANNLRDLDSDIKNHRYTLVYYIGRPNGIKLFQ
LLMYSSYLAIIIGFIFRIFEWPTLLSLLTFPIIRKNLKSHASQVPSPRSFVYSLRNMVLFNSAYAVSLFLSILWQYLSK
>Mature_318_residues
SLKNFLELVEIKTKIASIFPYIIGLLFSLSYFKMINIGLSLLFLIAMLLFDMTVTAINNYQDFKKAKDEDYKKQENIIGQ
ANLSTRLVASIILFMLILSLFLGFLLAYFVGWLFFILGGIVFFIGVFYTYGPIPLSRMPLGEIFSGGTMGFGIFAMIILI
NSAQSPIFNLNLDFTNDSFSFTGSIFAAIAMIIASLPLIFTIANIMLANNLRDLDSDIKNHRYTLVYYIGRPNGIKLFQL
LMYSSYLAIIIGFIFRIFEWPTLLSLLTFPIIRKNLKSHASQVPSPRSFVYSLRNMVLFNSAYAVSLFLSILWQYLSK

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004657
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 36264; Mature: 36133

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKNFLELVEIKTKIASIFPYIIGLLFSLSYFKMINIGLSLLFLIAMLLFDMTVTAINN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQDFKKAKDEDYKKQENIIGQANLSTRLVASIILFMLILSLFLGFLLAYFVGWLFFILGG
HHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVFFIGVFYTYGPIPLSRMPLGEIFSGGTMGFGIFAMIILINSAQSPIFNLNLDFTNDSF
HHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
SFTGSIFAAIAMIIASLPLIFTIANIMLANNLRDLDSDIKNHRYTLVYYIGRPNGIKLFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHH
LLMYSSYLAIIIGFIFRIFEWPTLLSLLTFPIIRKNLKSHASQVPSPRSFVYSLRNMVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NSAYAVSLFLSILWQYLSK
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLKNFLELVEIKTKIASIFPYIIGLLFSLSYFKMINIGLSLLFLIAMLLFDMTVTAINN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]