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The map label for this gene is ftsK

Identifier: 15673638

GI number: 15673638

Start: 1704238

End: 1706529

Strand: Reverse

Name: ftsK

Synonym: L0211

Alternate gene names: 15673638

Gene position: 1706529-1704238 (Counterclockwise)

Preceding gene: 15673640

Following gene: 15673637

Centisome position: 72.14

GC content: 38.0

Gene sequence:

>2292_bases
ATGAGTGAAAGTAAAAAAATGCCTGCAAAGAAAAAAACAACCAGAAGAAATACTAAAAAAGAACAACAGAAAAAGGCCGC
AACACGCAAAATGATTGCTTTTTTTGTTGGGCTTCTTTTAATCTTATTTGCGCTTGCTCGCCTAGGAATTGTCGGAGTCT
TACTTTATAACATTGTCCGCTTGTTTGTTGGTTCTCTTGCGATTGTTTTTCTTCTCTTGCTTGCTGGACTAATGATTATT
TCCGTCTTTCGTAAGCAAGTTTTAAAAGAAAATAAAAGAATTATTCCAGCCATTATTTTAACTTTTATCGGCCTAATGTT
TGTCTTTCAAATTCGACTTCATCAAGGATTTAATGAAACTTTTCATCTTATCTGGTCTGATTTAATGGCTGGCCGTGTCA
TTCATTTTGTTGGCTCAGGTGTCATTGGAGCATTAATCACCGAGCCTGCTAAAGCCTTGTTTTCAGTCATTGGTGTCTAT
ATTATTGCTGCAGTACTTTGGTTAGTTGCTATTTATCTCATGATTCCAGGACTTTTCCCTAAAATGCGTGAAGATTTACA
TCAACGTTTAGCGAAATGGAAAGAAAAGCATGCCGAAAAAGTAGAAGCTAAAAAAGCAGCGAAAGCACTTGCTGAGCTAG
AAAAAAAACAAGCCGTAGCAGAAAGAGAAGAGCTTCCAGAGGCAGCAGAAAATTCATTATTTACCTCAGCACCTACTGAA
ATTCCAATAAATATTCCAGAAGCGCCTTTTGAAGAAAATGAAACTGAAAGTCCAGTTTTAGCAGAAGTTCCTCTTGATGA
TGAACCTGTCAATTTTTCAAATACTAATAACTATAATGGTAACTATAAATTACCAACCATTGATTTACTGGCAGAAGTTC
CTGTCAAAAATCAATCAGGCGAACGTGAGAATGTTCGTAAAAATATTGGTATTTTAGAAGAAACTTTCAAATCTTTTGGA
ATTGGTGCCAATGTTGAATCGGCAGTCGTCGGTCCATCAATTACAAAATATGAAATCAAATTAGCGACTGGAACAAAAGT
TTCACGCGTTGTTAATTTATCAGATGATTTAGCATTAGCCTTAGCTGCTAAAGATATCCGAATTGAAGCACCAATTCCTG
GGAAATCTTTAGTCGGCGTCGAAATTCCTAATGCCGAAGTTGCAATGGTTGGTTTCCGCGAAATGTGGGAGGCTGGCAAA
ACTAATCCAAGCAAATTGTTAGAAATTCCTCTTGGTAAATCATTAGATGGTGGAATTCGCACATTTGATTTAACAAGAAT
GCCTCACTTATTGGTTGCAGGTTCAACTGGTTCAGGTAAATCAGTGGCGGTAAATGGTATTATTACTTCAATTTTGATGA
AAGCTTTGCCTAGTCAAGTGAAGTTTCTGATGGTTGACCCTAAAATGGTCGAACTTTCTGTTTACAATGATATTCCTCAT
CTATTGATTCCAGTCGTAACAAATCCACGTAAAGCTTCACGTGCCCTTCAAAAAGTTGTTGACCAAATGGAAGAACGCTA
TGAACTCTTTAGTCGTTATGGCGTCCGTAACATTGCTGGATATAATGAAAAAGTACAAAGATATAATGCAGAATCAGATG
AAAAAATGCTTGAACTTCCTCTGATTGTAGTCATTGTTGATGAATTAGCCGATTTAATGATGGTTGCCAGTAAAGAAGTG
GAAGATGCAATTATTCGTTTGGGACAAAAAGCTCGAGCAGCAGGGATTCATATGATTCTTGCGACACAACGTCCATCTGT
TGATGTCATTTCTGGACTAATTAAAGCAAATGTTCCTTCAAGAATTGCCTTTGCTGTTTCATCTGGAACAGATTCACGAA
CAATTTTAGATACTAATGGGGCTGAAAAATTACTAGGTCGTGGGGATATGCTCTTTAAACCTATTGATGAAAATCATCCG
ATTCGTTTGCAAGGGGCTTTCTTATCTGACGATGATGTCGAATCTGTTGTGACCTTTATTAAAGACCAATCAGAAGCTCA
ATATGACGAAAGCTTTGACCCTGGTGAGGTAGATGAAAGTCAAGTTGGTACGGGCGCTTCAAATACAGGCTCTGGTGACC
CCTTATTTGAAGAAGCACGAAATATGGTTATTATGGCTCAAAAAGCTTCAACGGCTCAATTGCAACGGGCTTTAAAAGTT
GGATTCAATCGCGCCTCTGACTTGATGAATGAGTTGGAAGCGCAGGGAATTGTTGGTCCTGCTAAAGGAACGACTCCTCG
TAAAGTCCTTGTTAGTCCAGATGGAGAATTTATTGGAGGAGTAGAAGAGTGA

Upstream 100 bases:

>100_bases
AATTTAAATGACTGACAGAACTGTCAGTTTGTGTTAACTATAAAAATAAATAAATATAATTAATATTATTTTACTGACAA
ACCTGTCAATATTATTAAAA

Downstream 100 bases:

>100_bases
GTGAAGAACTATATTATCGTCACTATTTTCTACAAATCTATGAAATCTTACGAGAAGATGAACAAAATAAAAAACTTTCA
ATCAAGGAAAAAAATGTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MSESKKMPAKKKTTRRNTKKEQQKKAATRKMIAFFVGLLLILFALARLGIVGVLLYNIVRLFVGSLAIVFLLLLAGLMII
SVFRKQVLKENKRIIPAIILTFIGLMFVFQIRLHQGFNETFHLIWSDLMAGRVIHFVGSGVIGALITEPAKALFSVIGVY
IIAAVLWLVAIYLMIPGLFPKMREDLHQRLAKWKEKHAEKVEAKKAAKALAELEKKQAVAEREELPEAAENSLFTSAPTE
IPINIPEAPFEENETESPVLAEVPLDDEPVNFSNTNNYNGNYKLPTIDLLAEVPVKNQSGERENVRKNIGILEETFKSFG
IGANVESAVVGPSITKYEIKLATGTKVSRVVNLSDDLALALAAKDIRIEAPIPGKSLVGVEIPNAEVAMVGFREMWEAGK
TNPSKLLEIPLGKSLDGGIRTFDLTRMPHLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPH
LLIPVVTNPRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELPLIVVIVDELADLMMVASKEV
EDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDTNGAEKLLGRGDMLFKPIDENHP
IRLQGAFLSDDDVESVVTFIKDQSEAQYDESFDPGEVDESQVGTGASNTGSGDPLFEEARNMVIMAQKASTAQLQRALKV
GFNRASDLMNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE

Sequences:

>Translated_763_residues
MSESKKMPAKKKTTRRNTKKEQQKKAATRKMIAFFVGLLLILFALARLGIVGVLLYNIVRLFVGSLAIVFLLLLAGLMII
SVFRKQVLKENKRIIPAIILTFIGLMFVFQIRLHQGFNETFHLIWSDLMAGRVIHFVGSGVIGALITEPAKALFSVIGVY
IIAAVLWLVAIYLMIPGLFPKMREDLHQRLAKWKEKHAEKVEAKKAAKALAELEKKQAVAEREELPEAAENSLFTSAPTE
IPINIPEAPFEENETESPVLAEVPLDDEPVNFSNTNNYNGNYKLPTIDLLAEVPVKNQSGERENVRKNIGILEETFKSFG
IGANVESAVVGPSITKYEIKLATGTKVSRVVNLSDDLALALAAKDIRIEAPIPGKSLVGVEIPNAEVAMVGFREMWEAGK
TNPSKLLEIPLGKSLDGGIRTFDLTRMPHLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPH
LLIPVVTNPRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELPLIVVIVDELADLMMVASKEV
EDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDTNGAEKLLGRGDMLFKPIDENHP
IRLQGAFLSDDDVESVVTFIKDQSEAQYDESFDPGEVDESQVGTGASNTGSGDPLFEEARNMVIMAQKASTAQLQRALKV
GFNRASDLMNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE
>Mature_762_residues
SESKKMPAKKKTTRRNTKKEQQKKAATRKMIAFFVGLLLILFALARLGIVGVLLYNIVRLFVGSLAIVFLLLLAGLMIIS
VFRKQVLKENKRIIPAIILTFIGLMFVFQIRLHQGFNETFHLIWSDLMAGRVIHFVGSGVIGALITEPAKALFSVIGVYI
IAAVLWLVAIYLMIPGLFPKMREDLHQRLAKWKEKHAEKVEAKKAAKALAELEKKQAVAEREELPEAAENSLFTSAPTEI
PINIPEAPFEENETESPVLAEVPLDDEPVNFSNTNNYNGNYKLPTIDLLAEVPVKNQSGERENVRKNIGILEETFKSFGI
GANVESAVVGPSITKYEIKLATGTKVSRVVNLSDDLALALAAKDIRIEAPIPGKSLVGVEIPNAEVAMVGFREMWEAGKT
NPSKLLEIPLGKSLDGGIRTFDLTRMPHLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPHL
LIPVVTNPRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELPLIVVIVDELADLMMVASKEVE
DAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDTNGAEKLLGRGDMLFKPIDENHPI
RLQGAFLSDDDVESVVTFIKDQSEAQYDESFDPGEVDESQVGTGASNTGSGDPLFEEARNMVIMAQKASTAQLQRALKVG
FNRASDLMNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=494, Percent_Identity=46.3562753036437, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_LACLA (Q9CF25)

Other databases:

- EMBL:   AE005176
- PIR:   H86831
- RefSeq:   NP_267812.1
- ProteinModelPortal:   Q9CF25
- SMR:   Q9CF25
- GeneID:   1115316
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0211
- NMPDR:   fig|272623.1.peg.1698
- HOGENOM:   HBG662140
- OMA:   INIPEAP
- ProtClustDB:   CLSK697865
- BioCyc:   LLAC272623:L0211-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 83628; Mature: 83497

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe74e4e0)-; HASH(0xf252784)-; HASH(0xf4bbf20)-; HASH(0xe9db9bc)-; HASH(0xf2525bc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESKKMPAKKKTTRRNTKKEQQKKAATRKMIAFFVGLLLILFALARLGIVGVLLYNIVR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVGSLAIVFLLLLAGLMIISVFRKQVLKENKRIIPAIILTFIGLMFVFQIRLHQGFNET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
FHLIWSDLMAGRVIHFVGSGVIGALITEPAKALFSVIGVYIIAAVLWLVAIYLMIPGLFP
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KMREDLHQRLAKWKEKHAEKVEAKKAAKALAELEKKQAVAEREELPEAAENSLFTSAPTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEECCCCCC
IPINIPEAPFEENETESPVLAEVPLDDEPVNFSNTNNYNGNYKLPTIDLLAEVPVKNQSG
CCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEECCHHHHHHCCCCCCCCC
ERENVRKNIGILEETFKSFGIGANVESAVVGPSITKYEIKLATGTKVSRVVNLSDDLALA
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEEEEEECCCCHHHEECCCCCHHHE
LAAKDIRIEAPIPGKSLVGVEIPNAEVAMVGFREMWEAGKTNPSKLLEIPLGKSLDGGIR
EEECCEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHCCCCCHHHEEECCCCCCCCCCCE
TFDLTRMPHLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPH
EEECCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHCHHHCEEEEECCEEEEEEECCCCCC
LLIPVVTNPRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELP
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHCCCCCCHHHHHHH
LIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCC
RIAFAVSSGTDSRTILDTNGAEKLLGRGDMLFKPIDENHPIRLQGAFLSDDDVESVVTFI
CEEEEEECCCCCCEEEECCCHHHHHCCCCCEEECCCCCCCEEEEECCCCCCHHHHHHHHH
KDQSEAQYDESFDPGEVDESQVGTGASNTGSGDPLFEEARNMVIMAQKASTAQLQRALKV
HCCCHHCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHH
GFNRASDLMNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCH
>Mature Secondary Structure 
SESKKMPAKKKTTRRNTKKEQQKKAATRKMIAFFVGLLLILFALARLGIVGVLLYNIVR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVGSLAIVFLLLLAGLMIISVFRKQVLKENKRIIPAIILTFIGLMFVFQIRLHQGFNET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
FHLIWSDLMAGRVIHFVGSGVIGALITEPAKALFSVIGVYIIAAVLWLVAIYLMIPGLFP
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KMREDLHQRLAKWKEKHAEKVEAKKAAKALAELEKKQAVAEREELPEAAENSLFTSAPTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEECCCCCC
IPINIPEAPFEENETESPVLAEVPLDDEPVNFSNTNNYNGNYKLPTIDLLAEVPVKNQSG
CCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEECCHHHHHHCCCCCCCCC
ERENVRKNIGILEETFKSFGIGANVESAVVGPSITKYEIKLATGTKVSRVVNLSDDLALA
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCEEEEEEEECCCCHHHEECCCCCHHHE
LAAKDIRIEAPIPGKSLVGVEIPNAEVAMVGFREMWEAGKTNPSKLLEIPLGKSLDGGIR
EEECCEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHCCCCCHHHEEECCCCCCCCCCCE
TFDLTRMPHLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPH
EEECCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHCHHHCEEEEECCEEEEEEECCCCCC
LLIPVVTNPRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELP
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHCCCCCCHHHHHHH
LIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCC
RIAFAVSSGTDSRTILDTNGAEKLLGRGDMLFKPIDENHPIRLQGAFLSDDDVESVVTFI
CEEEEEECCCCCCEEEECCCHHHHHCCCCCEEECCCCCCCEEEEECCCCCCHHHHHHHHH
KDQSEAQYDESFDPGEVDESQVGTGASNTGSGDPLFEEARNMVIMAQKASTAQLQRALKV
HCCCHHCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHH
GFNRASDLMNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE
CCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471