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The map label for this gene is gpsA

Identifier: 15673320

GI number: 15673320

Start: 1376785

End: 1377810

Strand: Direct

Name: gpsA

Synonym: L0016

Alternate gene names: 15673320

Gene position: 1376785-1377810 (Clockwise)

Preceding gene: 15673312

Following gene: 15673321

Centisome position: 58.2

GC content: 39.57

Gene sequence:

>1026_bases
ATGAATCCACAAAAAATTGCAGTTTTAGGACCAGGTTCGTGGGGAACTGCACTTTCACAAGTTCTTAATGATAATGGTCA
TGAAGTTCGTATCTGGGGAAATAACCCAGAACAGATGGCTGAAATTAATGAAAAGCATACAAATACACGCTATTTTAAAG
ATGTTGTTTTGGATGAAAAAATAAAAGCATTTGATCGTTTAGATTTAGCTTTAGAAGACGTTGATGCTATTTTATTTGTT
GTACCAACTAAAGTGACACGTTTGGTCGCAAAACAAGTAGCCGAAGTCCTTAAACACAAAGTACACATTCTTCACGCTTC
TAAAGGGCTTGAACAAGGGACACATGAGCGAATTTCTACTATTCTTGAAGAAGAAATCCCCGCTCAATTGCGAGGAGAAA
TCGTGGTAGTTTCTGGCCCTTCTCATGCTGAAGAAACAATTGTTCGTGATATTACTTTAATTTCTGCAGCTTCTAAAGAC
CATGATGAAGCGAAATACGCTCAAGCAATCTTTAGCAACGACTACTTCCGTCTGTATACTAATACTGATGTTATTGGTGT
TGAAACAGCTGGCGCCCTTAAAAATATTATTGCTGTAGGTGCGGGTGCTCTGCACGGTCTTGGTTTTGGTGATAATGCTA
AAGCAGCAATTATTACACGTGGCCTTGCCGAAATTACTCGTTTAGGTGTGGCTATGGGAGCTGAACCTTTAACTTATAGC
GGTTTGTCTGGTGTTGGTGACTTAATTGTAACAGGTACTTCAATTCACTCACGAAACTGGCGCGCGGGTGATGCTCTTGG
TCGCGGCGAAAAGCTAGCTGATATTGAAAAAAATATGGGAATGGTTATTGAAGGTGTTTCAACCACTAAAGCTGCTTTTG
AGCTCGCTCAACAGCTAGGTATCGATATGCCAATTACCGAGACAATCTACAAAGTTCTCTATGAAAATCTAGATGCAAAA
ACTGGAATTCTTGATATCATGCGCCGCGAAACTCGTGCCGAAAATGAATTCATTAATAATAAATAA

Upstream 100 bases:

>100_bases
TATCATAATATTTGAACCCTAAATCATACTTAGGGCTGATTTTTATTCTTGCTTATGTTAAAATGTAAAGGAAACCAAAA
CGAAAGAAAGGATCATTTCT

Downstream 100 bases:

>100_bases
AGAGTAAATACGATTTATCTAACTATAAAGGAGTTAATTATCCATGAAACAAAACATTATTCCAACTAAAGCCCGAAAAG
TACGTAAAGCTGTTATTCCT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNPEQMAEINEKHTNTRYFKDVVLDEKIKAFDRLDLALEDVDAILFV
VPTKVTRLVAKQVAEVLKHKVHILHASKGLEQGTHERISTILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASKD
HDEAKYAQAIFSNDYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKLADIEKNMGMVIEGVSTTKAAFELAQQLGIDMPITETIYKVLYENLDAK
TGILDIMRRETRAENEFINNK

Sequences:

>Translated_341_residues
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNPEQMAEINEKHTNTRYFKDVVLDEKIKAFDRLDLALEDVDAILFV
VPTKVTRLVAKQVAEVLKHKVHILHASKGLEQGTHERISTILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASKD
HDEAKYAQAIFSNDYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKLADIEKNMGMVIEGVSTTKAAFELAQQLGIDMPITETIYKVLYENLDAK
TGILDIMRRETRAENEFINNK
>Mature_341_residues
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNPEQMAEINEKHTNTRYFKDVVLDEKIKAFDRLDLALEDVDAILFV
VPTKVTRLVAKQVAEVLKHKVHILHASKGLEQGTHERISTILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASKD
HDEAKYAQAIFSNDYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKLADIEKNMGMVIEGVSTTKAAFELAQQLGIDMPITETIYKVLYENLDAK
TGILDIMRRETRAENEFINNK

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI24307999, Length=336, Percent_Identity=28.2738095238095, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI33695088, Length=335, Percent_Identity=28.6567164179104, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=40.1812688821752, Blast_Score=244, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI32564403, Length=342, Percent_Identity=27.4853801169591, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI193210136, Length=342, Percent_Identity=27.4853801169591, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32564399, Length=335, Percent_Identity=27.7611940298507, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI193210134, Length=333, Percent_Identity=25.5255255255255, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17507425, Length=335, Percent_Identity=25.9701492537313, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320181, Length=347, Percent_Identity=30.5475504322767, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324513, Length=345, Percent_Identity=27.2463768115942, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI17136202, Length=342, Percent_Identity=27.4853801169591, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136200, Length=342, Percent_Identity=27.4853801169591, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136204, Length=342, Percent_Identity=27.4853801169591, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI22026922, Length=336, Percent_Identity=24.4047619047619, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45551945, Length=235, Percent_Identity=24.6808510638298, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362270, Length=235, Percent_Identity=24.2553191489362, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 37145; Mature: 37145

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNPEQMAEINEKHTNTRYFKDVVLDEK
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHH
IKAFDRLDLALEDVDAILFVVPTKVTRLVAKQVAEVLKHKVHILHASKGLEQGTHERIST
HHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASKDHDEAKYAQAIFSNDYFRLYT
HHHHHCCHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEC
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKLADIEKNMGMVIEGVSTTKAAFELAQQLG
CCCCCCCEEEECCEEECCCCCCCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHC
IDMPITETIYKVLYENLDAKTGILDIMRRETRAENEFINNK
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNPEQMAEINEKHTNTRYFKDVVLDEK
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHH
IKAFDRLDLALEDVDAILFVVPTKVTRLVAKQVAEVLKHKVHILHASKGLEQGTHERIST
HHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASKDHDEAKYAQAIFSNDYFRLYT
HHHHHCCHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEC
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKLADIEKNMGMVIEGVSTTKAAFELAQQLG
CCCCCCCEEEECCEEECCCCCCCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHC
IDMPITETIYKVLYENLDAKTGILDIMRRETRAENEFINNK
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA