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The map label for this gene is rdrB

Identifier: 15673279

GI number: 15673279

Start: 1331842

End: 1332603

Strand: Direct

Name: rdrB

Synonym: L0153

Alternate gene names: 15673279

Gene position: 1331842-1332603 (Clockwise)

Preceding gene: 15673271

Following gene: 15673280

Centisome position: 56.3

GC content: 31.76

Gene sequence:

>762_bases
ATGTTATTAGAAGAAAGACTATCCCAAATTAGCCAAATCATTGATAAAGAAGGCAGTGCCACAATTGATTTTCTAGCTCA
AAAACTTGAAGTTTCAAAAGATACAATTAGGAGAGATTTAATAAAGTTAGAATCCAGAAAAAAATTGCATCGAGTTCATG
GTGGAGCAATTCCAATCGGCAAAGAGGCTGAGATTTTGAATTATGAAGAACGCTCAAATATTTCCACCAGTTTAAAGAAA
AAAATAGCAAGTAAAATAAAAAATCTCATAAAAGATCATAGCACTCTCATTTTTGATTCATCAACAACCGTCGAAGTTGC
TATAAAACAACTTGATAACTTCTCTATCTCAACCATCACAAACTCCCTCACCAATGCAATATTACTTTCGAAGTATGAGA
TGGCAACTGTACAACTTCTTCCCGGAAAATTAAACAAGAATCAACTATTCTTGTACGGTGCGGAAACCGTTGAAAAACTC
TCTCAATATCAAGTTGATTTTACAATTTTAGGCGTTTTTGCTCTTTCTAATAATGGTTTATTTATTCATACTGAAGAGGA
AGGCCTCGTCAAAAGAAAAATGATTCAACAAGGAAAGCAAGTCATAGCCATAGCAGATCATACCAAACTTAATAAAGAAG
GATTCTTTAAAATTTGTGATTTAAAAGAAATAGACTATCTCATCACCGATGAAAAAATTGAAGGTGAATTGATGAATAAT
TTAAATGATAATAATGTGAAAGTGGTGACTATAAATGAATAA

Upstream 100 bases:

>100_bases
TTTTGCATTAACTTGCATTTTTGGCATATTTTCGATTAAACAATTGCAACTTATTGCTTATTTTCGTGTGCTGTGTTATG
ATAGTTAAAAAGGAGAGAGA

Downstream 100 bases:

>100_bases
AGAAATTATTTACGAAAAAATAAACGAACCAAAGCTCTTTAATAATGTTCCACCGGTTACACTAACTGACAAAACATTAA
AGGACCGAAAAGAAAAGCTT

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLLEERLSQISQIIDKEGSATIDFLAQKLEVSKDTIRRDLIKLESRKKLHRVHGGAIPIGKEAEILNYEERSNISTSLKK
KIASKIKNLIKDHSTLIFDSSTTVEVAIKQLDNFSISTITNSLTNAILLSKYEMATVQLLPGKLNKNQLFLYGAETVEKL
SQYQVDFTILGVFALSNNGLFIHTEEEGLVKRKMIQQGKQVIAIADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMNN
LNDNNVKVVTINE

Sequences:

>Translated_253_residues
MLLEERLSQISQIIDKEGSATIDFLAQKLEVSKDTIRRDLIKLESRKKLHRVHGGAIPIGKEAEILNYEERSNISTSLKK
KIASKIKNLIKDHSTLIFDSSTTVEVAIKQLDNFSISTITNSLTNAILLSKYEMATVQLLPGKLNKNQLFLYGAETVEKL
SQYQVDFTILGVFALSNNGLFIHTEEEGLVKRKMIQQGKQVIAIADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMNN
LNDNNVKVVTINE
>Mature_253_residues
MLLEERLSQISQIIDKEGSATIDFLAQKLEVSKDTIRRDLIKLESRKKLHRVHGGAIPIGKEAEILNYEERSNISTSLKK
KIASKIKNLIKDHSTLIFDSSTTVEVAIKQLDNFSISTITNSLTNAILLSKYEMATVQLLPGKLNKNQLFLYGAETVEKL
SQYQVDFTILGVFALSNNGLFIHTEEEGLVKRKMIQQGKQVIAIADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMNN
LNDNNVKVVTINE

Specific function: Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788069, Length=252, Percent_Identity=32.1428571428571, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=29.2490118577075, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=29.2490118577075, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789829, Length=246, Percent_Identity=27.6422764227642, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1789059, Length=255, Percent_Identity=26.2745098039216, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI226510968, Length=235, Percent_Identity=24.2553191489362, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789170, Length=219, Percent_Identity=26.4840182648402, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28594; Mature: 28594

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEERLSQISQIIDKEGSATIDFLAQKLEVSKDTIRRDLIKLESRKKLHRVHGGAIPIG
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KEAEILNYEERSNISTSLKKKIASKIKNLIKDHSTLIFDSSTTVEVAIKQLDNFSISTIT
CCCCEECCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCHHHHH
NSLTNAILLSKYEMATVQLLPGKLNKNQLFLYGAETVEKLSQYQVDFTILGVFALSNNGL
HHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEEEEECCCCE
FIHTEEEGLVKRKMIQQGKQVIAIADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMNN
EEEECCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEECCHHHHHHHHC
LNDNNVKVVTINE
CCCCCEEEEEECC
>Mature Secondary Structure
MLLEERLSQISQIIDKEGSATIDFLAQKLEVSKDTIRRDLIKLESRKKLHRVHGGAIPIG
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KEAEILNYEERSNISTSLKKKIASKIKNLIKDHSTLIFDSSTTVEVAIKQLDNFSISTIT
CCCCEECCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCHHHHH
NSLTNAILLSKYEMATVQLLPGKLNKNQLFLYGAETVEKLSQYQVDFTILGVFALSNNGL
HHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEEEEECCCCE
FIHTEEEGLVKRKMIQQGKQVIAIADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMNN
EEEECCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEECCHHHHHHHHC
LNDNNVKVVTINE
CCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]