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The map label for this gene is ylgG

Identifier: 15673138

GI number: 15673138

Start: 1168309

End: 1168806

Strand: Direct

Name: ylgG

Synonym: L168057

Alternate gene names: 15673138

Gene position: 1168309-1168806 (Clockwise)

Preceding gene: 15673137

Following gene: 15673139

Centisome position: 49.39

GC content: 32.93

Gene sequence:

>498_bases
ATGAATGAAGACCTAATTGCTGAAATTCAAGCTTTATCTGCTATTGGAAGTGAAGAAAAATTTTCCGAGATTATTCGATT
ATTGAAAAATTCGACTTTAGAGCTTCGGGGGAAAAAGAATCCAGATTTACAATTGTCAGCAAGTGCATTAGTTTTTAAAA
AACATAAACTATTTTTTATTGAACACCCTTATCAAAAGGAGCTTTTGCTTCCAGCAGGTCATGTTGAACTAGGAGAAAAG
CCATTGGAAACTGCGATTCGTGAGTTCCATGAAGAAACAGGTTTTTCAGCGTCAGAATCAGGCAAGTTGGTAGATGTTAA
CTTGATTAATATTCCTTACAACAAAATTAAGAATGAGAAAGAACATCAACACATTGATTTTCGTTTTCTATTGGAACTAA
AAGAAAAAGAAGCAGGCCTTGCTGAATTGCCTTTTTTCCTTCTTGATAGAACTGAAGCTCCTGATGAATTTAAAAAATAT
TATCAATACAAAAGATAA

Upstream 100 bases:

>100_bases
CGCAAATGGTTGCTGATGGGGGACGGATTTTGCGTGTTCATGATGTTAAGGAGACTAAACGTTTACTCGATGCAATTGAA
ATTTATAAGGAATTTTAAAA

Downstream 100 bases:

>100_bases
AGTAGAAAAGGTCACAAAATGTCTATAGAAGAAGCATTGGAATGGATACATTCACGTTTAAAATTTAATATTCGCCCAGG
CCTAAGTCGTGTTTCGGCCC

Product: hypothetical protein

Products: NA

Alternate protein names: Dihydroneopterin triphosphate pyrophosphohydrolase

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNEDLIAEIQALSAIGSEEKFSEIIRLLKNSTLELRGKKNPDLQLSASALVFKKHKLFFIEHPYQKELLLPAGHVELGEK
PLETAIREFHEETGFSASESGKLVDVNLINIPYNKIKNEKEHQHIDFRFLLELKEKEAGLAELPFFLLDRTEAPDEFKKY
YQYKR

Sequences:

>Translated_165_residues
MNEDLIAEIQALSAIGSEEKFSEIIRLLKNSTLELRGKKNPDLQLSASALVFKKHKLFFIEHPYQKELLLPAGHVELGEK
PLETAIREFHEETGFSASESGKLVDVNLINIPYNKIKNEKEHQHIDFRFLLELKEKEAGLAELPFFLLDRTEAPDEFKKY
YQYKR
>Mature_165_residues
MNEDLIAEIQALSAIGSEEKFSEIIRLLKNSTLELRGKKNPDLQLSASALVFKKHKLFFIEHPYQKELLLPAGHVELGEK
PLETAIREFHEETGFSASESGKLVDVNLINIPYNKIKNEKEHQHIDFRFLLELKEKEAGLAELPFFLLDRTEAPDEFKKY
YQYKR

Specific function: Probably mediates the removal of pyrophosphate from dihydroneopterin triphosphate (DHNTP), a possible step in the pterin branch of the folate synthesis pathway

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FOLQ_LACLA (Q9CGE1)

Other databases:

- EMBL:   AE005176
- PIR:   D86769
- RefSeq:   NP_267312.1
- ProteinModelPortal:   Q9CGE1
- SMR:   Q9CGE1
- GeneID:   1114798
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L168057
- NMPDR:   fig|272623.1.peg.1190
- HOGENOM:   HBG516999
- OMA:   INCAVRE
- ProtClustDB:   CLSK876846
- BioCyc:   LLAC272623:L168057-MONOMER
- BioCyc:   MetaCyc:MONOMER-13396
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: NA

Molecular weight: Translated: 19157; Mature: 19157

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEDLIAEIQALSAIGSEEKFSEIIRLLKNSTLELRGKKNPDLQLSASALVFKKHKLFFI
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEHHHEEEEECEEEEE
EHPYQKELLLPAGHVELGEKPLETAIREFHEETGFSASESGKLVDVNLINIPYNKIKNEK
ECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHCCCC
EHQHIDFRFLLELKEKEAGLAELPFFLLDRTEAPDEFKKYYQYKR
HHHCCCHHHEEEHHHHCCCHHHCCHHEECCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MNEDLIAEIQALSAIGSEEKFSEIIRLLKNSTLELRGKKNPDLQLSASALVFKKHKLFFI
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEHHHEEEEECEEEEE
EHPYQKELLLPAGHVELGEKPLETAIREFHEETGFSASESGKLVDVNLINIPYNKIKNEK
ECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHCCCC
EHQHIDFRFLLELKEKEAGLAELPFFLLDRTEAPDEFKKYYQYKR
HHHCCCHHHEEEHHHHCCCHHHCCHHEECCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471