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The map label for this gene is trxB1

Identifier: 15672922

GI number: 15672922

Start: 965452

End: 966378

Strand: Direct

Name: trxB1

Synonym: L0196

Alternate gene names: 15672922

Gene position: 965452-966378 (Clockwise)

Preceding gene: 30024013

Following gene: 15672923

Centisome position: 40.81

GC content: 38.73

Gene sequence:

>927_bases
ATGACAGAAAAGAAATATGATGTTGTCATCATTGGTTCAGGCCCTGCGGGAATGACTGCAGCGATGTATACTGCACGTTC
TGAAATGAAAACTTTGCTTTTAGAACGTGGTGTTCCTGGTGGTCAAATGAATAACACAGCTGAGATTGAAAATTATCCTG
GCTATGAAACAATCATGGGTCCTGAACTTTCAATGAAAATGGCTGAACCTTTGGAAGGTTTAGGTGTAGAAAATGCTTAT
GGTTTTGTGACGGCTATTGAAGACCATGGGGATTACAAAAAAATTATCACAGAAGATGATGAGTTTGTCACTAAATCAAT
TATTATTGCGACAGGAGCTAATCACCGTAAGCTTGAAATTCCCGGTGAGGAAGAATATGGAGCTCGCGGAGTTTCCTACT
GTGCCGTTTGTGATGGTGCTTTCTTTAGAAACCAAGAAATTTTAGTTATTGGTGGTGGTGACTCTGCTGTTGAAGAAGCT
CTCTACTTGACTCGTTTTGGTCAATCAGTAACAATTATGCATCGTCGTGATAAATTGCGTGCACAAGAAATTATCCAACA
AAGAGCTTTCAAAGAAGAAAAAATCAACTTTATTTGGGATTCTGTTCCTATGGAAATTAAAGGGGATGACAAAAAAGTTC
AATCCGTTGTTTATAAAAACGTTAAAACGGGTGAAGTAACTGAAAAAGCTTTTGGTGGAATCTTCATTTATGTGGGACTT
GACCCAGTTGCTGAATTTGCTGGTAATCTTGGAATTACTGATGAAGCCGGTTGGATTATTACCGATGACCATATGAGAAC
AAGTCTACCTGGTATTTTTGCCGTAGGTGATGTTCGTCAAAAAGATTTCCGTCAAATCACTACAGCTATTGGTGATGGAG
CGCAAGCAGCTCAAGAAGCTTATAAATTTGTAGCTGAACTTGATTAA

Upstream 100 bases:

>100_bases
GTTTTTAGAACTAATAAAAAATGGCTCAAGTTTGCTGAAATGCTAGCTTGAGTTTATGAATTTAAGGGGAGTTCTTTAGC
TCTTAGAAAAGGGATTAAAA

Downstream 100 bases:

>100_bases
AATAAAAAATTACTGACAAAATCGTCAGTAATTTTTTATTAAAGGATTCGGAATGACTTTTAATCGAAAATATGGTAAAA
TGTAAGTAACGCAATTTTGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMGPELSMKMAEPLEGLGVENAY
GFVTAIEDHGDYKKIITEDDEFVTKSIIIATGANHRKLEIPGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEA
LYLTRFGQSVTIMHRRDKLRAQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKVQSVVYKNVKTGEVTEKAFGGIFIYVGL
DPVAEFAGNLGITDEAGWIITDDHMRTSLPGIFAVGDVRQKDFRQITTAIGDGAQAAQEAYKFVAELD

Sequences:

>Translated_308_residues
MTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMGPELSMKMAEPLEGLGVENAY
GFVTAIEDHGDYKKIITEDDEFVTKSIIIATGANHRKLEIPGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEA
LYLTRFGQSVTIMHRRDKLRAQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKVQSVVYKNVKTGEVTEKAFGGIFIYVGL
DPVAEFAGNLGITDEAGWIITDDHMRTSLPGIFAVGDVRQKDFRQITTAIGDGAQAAQEAYKFVAELD
>Mature_307_residues
TEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMGPELSMKMAEPLEGLGVENAYG
FVTAIEDHGDYKKIITEDDEFVTKSIIIATGANHRKLEIPGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEAL
YLTRFGQSVTIMHRRDKLRAQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKVQSVVYKNVKTGEVTEKAFGGIFIYVGLD
PVAEFAGNLGITDEAGWIITDDHMRTSLPGIFAVGDVRQKDFRQITTAIGDGAQAAQEAYKFVAELD

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI148277065, Length=246, Percent_Identity=28.0487804878049, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI33519430, Length=246, Percent_Identity=28.0487804878049, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI33519428, Length=246, Percent_Identity=28.0487804878049, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI33519426, Length=246, Percent_Identity=28.0487804878049, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI148277071, Length=246, Percent_Identity=28.0487804878049, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787114, Length=314, Percent_Identity=37.2611464968153, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=32.7868852459016, Blast_Score=154, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=42.6751592356688, Blast_Score=232, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=38.6581469648562, Blast_Score=203, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24640551, Length=212, Percent_Identity=28.3018867924528, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640549, Length=212, Percent_Identity=28.3018867924528, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640553, Length=212, Percent_Identity=28.3018867924528, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33895; Mature: 33764

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMG
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECC
PELSMKMAEPLEGLGVENAYGFVTAIEDHGDYKKIITEDDEFVTKSIIIATGANHRKLEI
CCCCHHHHCCHHHCCCCCCCEEEEEEECCCCCHHHCCCCHHHEEEEEEEEECCCCEEEEC
PGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKLR
CCCCCCCCCCCEEEEEECCCEECCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEHHHHHH
AQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKVQSVVYKNVKTGEVTEKAFGGIFIYVGL
HHHHHHHHHHHHHCCEEEECCCCEEECCCHHHHHHHHHCCCCCCCHHHHHCCCEEEEECC
DPVAEFAGNLGITDEAGWIITDDHMRTSLPGIFAVGDVRQKDFRQITTAIGDGAQAAQEA
CHHHHHHCCCCCCCCCCEEEECCCHHHCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHH
YKFVAELD
HHHHHCCC
>Mature Secondary Structure 
TEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYETIMG
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECC
PELSMKMAEPLEGLGVENAYGFVTAIEDHGDYKKIITEDDEFVTKSIIIATGANHRKLEI
CCCCHHHHCCHHHCCCCCCCEEEEEEECCCCCHHHCCCCHHHEEEEEEEEECCCCEEEEC
PGEEEYGARGVSYCAVCDGAFFRNQEILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKLR
CCCCCCCCCCCEEEEEECCCEECCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEHHHHHH
AQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKVQSVVYKNVKTGEVTEKAFGGIFIYVGL
HHHHHHHHHHHHHCCEEEECCCCEEECCCHHHHHHHHHCCCCCCCHHHHHCCCEEEEECC
DPVAEFAGNLGITDEAGWIITDDHMRTSLPGIFAVGDVRQKDFRQITTAIGDGAQAAQEA
CHHHHHHCCCCCCCCCCEEEECCCHHHCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHH
YKFVAELD
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]