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The map label for this gene is icaB

Identifier: 15672664

GI number: 15672664

Start: 682537

End: 683367

Strand: Direct

Name: icaB

Synonym: L82521

Alternate gene names: 15672664

Gene position: 682537-683367 (Clockwise)

Preceding gene: 15672663

Following gene: 15672665

Centisome position: 28.85

GC content: 31.77

Gene sequence:

>831_bases
TTGCGGTCCACACGTGAAACAAAAAAATATGTAAAAGATGGAAAAAAGGAGCAGCCAGATTTTGCTTATGAGAGTTTGCT
TAAAGACAATGATGGAATTATTGTTCTTTGTTATCACCGTGTGTTAAAAGATACGGTGGTTACAAATTTCGCTTATTCAA
TTTCGCATAATTCTCAACTCCATGAATATAATGTATTCTTGCAAGATTTTGAACAGCAAATGACATTTTTAAAGAAAAAT
CATATTAAAGTTTTGACTAGTTCAGAACTGATAGAGAAGCTTAATAAAAAAGAGGTCATTGGCAAAGCAGTAGTGATTAC
TTTTGATGACATTGATAAGTCTTTACCAGAGAACGCTTATCCAATAATGAAAAAATTAGACTTACCCTTTACGCAATTCA
TTATCACGGGAAAAGTTGGACAAACCATTGATGGTTCACAAATGTCGACTTGGAAAGAAATAAAGAAAATGAATGAAAAT
CCTTTGGTTACTTCAGGACTACATACGAATGACTTACATTATCAAGAAAACTTTGAACCGATTTTATCTACTAATATTTC
AAAAAAAGTAGTGCAAAAAGATTACCAGAAAAGTCAGAAAGCATTTGATGAGAAGTTAGATCAAAAAGGAAAAGTTTTTG
CTTATCCTTATGGAGCACAAAATAAAGACTTAGAAGATTATATGCTACAAGATGGAATTCAAGGAATATTCACACTATCT
CCAGGTGTAGTGACTAATGAAACACTATATAGTAATATTCCTAGGTTGATTGTTACGAAGGATAATTGGAAAACTATCAA
ACATTGGCTCTTAAGTGAAGGGACACAATAA

Upstream 100 bases:

>100_bases
TCGCCGCTATCGAGTATTGGATGAACCATTATCCAAGAAAAATGTTCAACTATAAGAGTTCATATGAGATGAGCTTGGCT
GGCTAACTTGGACTTGCAAT

Downstream 100 bases:

>100_bases
TAAGAGAAAATAAGAAGGAGATATTCATGAAGGCGAAGAATAAGTCATTTAAATTATTAATGGTTCTGAGTTTATTGATG
TGCTTGGTTGGAATTAATTT

Product: intercellular adhesion protein

Products: NA

Alternate protein names: PNAG N-deacetylase; Poly-beta-1,6-GlcNAc N-deacetylase; Biofilm polysaccharide intercellular adhesin deacetylase; Biofilm PIA deacetylase; Intercellular adhesion protein B [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRSTRETKKYVKDGKKEQPDFAYESLLKDNDGIIVLCYHRVLKDTVVTNFAYSISHNSQLHEYNVFLQDFEQQMTFLKKN
HIKVLTSSELIEKLNKKEVIGKAVVITFDDIDKSLPENAYPIMKKLDLPFTQFIITGKVGQTIDGSQMSTWKEIKKMNEN
PLVTSGLHTNDLHYQENFEPILSTNISKKVVQKDYQKSQKAFDEKLDQKGKVFAYPYGAQNKDLEDYMLQDGIQGIFTLS
PGVVTNETLYSNIPRLIVTKDNWKTIKHWLLSEGTQ

Sequences:

>Translated_276_residues
MRSTRETKKYVKDGKKEQPDFAYESLLKDNDGIIVLCYHRVLKDTVVTNFAYSISHNSQLHEYNVFLQDFEQQMTFLKKN
HIKVLTSSELIEKLNKKEVIGKAVVITFDDIDKSLPENAYPIMKKLDLPFTQFIITGKVGQTIDGSQMSTWKEIKKMNEN
PLVTSGLHTNDLHYQENFEPILSTNISKKVVQKDYQKSQKAFDEKLDQKGKVFAYPYGAQNKDLEDYMLQDGIQGIFTLS
PGVVTNETLYSNIPRLIVTKDNWKTIKHWLLSEGTQ
>Mature_276_residues
MRSTRETKKYVKDGKKEQPDFAYESLLKDNDGIIVLCYHRVLKDTVVTNFAYSISHNSQLHEYNVFLQDFEQQMTFLKKN
HIKVLTSSELIEKLNKKEVIGKAVVITFDDIDKSLPENAYPIMKKLDLPFTQFIITGKVGQTIDGSQMSTWKEIKKMNEN
PLVTSGLHTNDLHYQENFEPILSTNISKKVVQKDYQKSQKAFDEKLDQKGKVFAYPYGAQNKDLEDYMLQDGIQGIFTLS
PGVVTNETLYSNIPRLIVTKDNWKTIKHWLLSEGTQ

Specific function: Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl- D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introd

COG id: COG0726

COG function: function code G; Predicted xylanase/chitin deacetylase

Gene ontology:

Cell location: Secreted, cell wall. Note=Attached to the cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide deacetylase family [H]

Homologues:

Organism=Escherichia coli, GI1786322, Length=210, Percent_Identity=27.1428571428571, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011330
- InterPro:   IPR002509 [H]

Pfam domain/function: PF01522 Polysacc_deac_1 [H]

EC number: NA

Molecular weight: Translated: 31884; Mature: 31884

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTRETKKYVKDGKKEQPDFAYESLLKDNDGIIVLCYHRVLKDTVVTNFAYSISHNSQL
CCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHEEECCCCCH
HEYNVFLQDFEQQMTFLKKNHIKVLTSSELIEKLNKKEVIGKAVVITFDDIDKSLPENAY
HHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCEEEEEEECHHHHHCCCCHH
PIMKKLDLPFTQFIITGKVGQTIDGSQMSTWKEIKKMNENPLVTSGLHTNDLHYQENFEP
HHHHHCCCCHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCHHCCCH
ILSTNISKKVVQKDYQKSQKAFDEKLDQKGKVFAYPYGAQNKDLEDYMLQDGIQGIFTLS
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEC
PGVVTNETLYSNIPRLIVTKDNWKTIKHWLLSEGTQ
CCCEECHHHHHCCCEEEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSTRETKKYVKDGKKEQPDFAYESLLKDNDGIIVLCYHRVLKDTVVTNFAYSISHNSQL
CCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHEEECCCCCH
HEYNVFLQDFEQQMTFLKKNHIKVLTSSELIEKLNKKEVIGKAVVITFDDIDKSLPENAY
HHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCEEEEEEECHHHHHCCCCHH
PIMKKLDLPFTQFIITGKVGQTIDGSQMSTWKEIKKMNENPLVTSGLHTNDLHYQENFEP
HHHHHCCCCHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCHHCCCH
ILSTNISKKVVQKDYQKSQKAFDEKLDQKGKVFAYPYGAQNKDLEDYMLQDGIQGIFTLS
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEC
PGVVTNETLYSNIPRLIVTKDNWKTIKHWLLSEGTQ
CCCEECHHHHHCCCEEEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA