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The map label for this gene is bglS

Identifier: 15672157

GI number: 15672157

Start: 179668

End: 181104

Strand: Direct

Name: bglS

Synonym: L179659

Alternate gene names: 15672157

Gene position: 179668-181104 (Clockwise)

Preceding gene: 30023977

Following gene: 15672158

Centisome position: 7.6

GC content: 38.48

Gene sequence:

>1437_bases
ATGGAGCACAAAAAATTAAAAGCATTTCCAAATGATTTTCTATGGGGTTCGGCTTCGGCAGCCTATCAAGTTGAGGGAGC
ACCTTTTGAAGATGGCAAAAAAGCCAGTGTCTGGGATAATTTTGTCCGTATTCCAGGCAAGACTTTTAAAGGAACGAATG
GGGATGTCGCTGTTGATCATTATCATCGCTATAAAGAAGATGTGGCTTTAATGAAAGAGTTGGGCCTTAAATCCTACCGT
TTTTCAATTGCTTGGACGCGGATTTTACCTGACGGACGTGGCGAAGTCAATCAAGCAGGCTTGAAATTCTATGAAGATTT
GATTGATGAGTTGATTGCTAATGAGATTGAACCAATTGTCACGATTTATCATTGGGATTTGCCCCAAGCCTTAGAAGATT
TATATGGTGGTTGGGAATCACGAGAAATTATCGCAGATTTTGTTAACTATGCTGAAGTTTTGTTTAATGCTTTTAAAGGT
AAAGTAAAATATTGGGTATCGCTTAATGAACAAAATATTTTTACAAGTCAAGGTTGGTCACTCGCGACTCACCCACCTGG
AAAAAGAGATATGAAACTTTTTTATCAGGTCAATCATATTGCTAATCTGACAAATGCTGCGGTAATCAATAAATTTCATG
AACTTGAAATGGATGGACAAATTGGCCCTTCGTTTGCCTATACGCCACAATATGCTAAGGATTCTGACCCACTCAATGTT
TTAGCGGCTGAAAATGCAGAAGAGCTTTATAGTCACTTTTGGATGGATGTTTATCTTTACGGAGAATACCCAATTGCGGC
AATGGCTTATTTACGTGAAAATGGGCTAGCACCTGAATTTGAAGCTGGGGATGCTGAACTTTTGAAATCAGCTAAACCTG
ATTTTCTAGGTATTAATTATTACCAGACAGCTACTAACGCATGGAATCCAGTTGACGGAGGAGTTGGAGTCGGTTCCTTT
AATACAAGTGGCAAAAAAGGAACAACCAAAGAATCAGGAATTCCAGGCCTCCATAAAAAAATTCAAAATCCTTTTATTGA
CCGAACAAATTGGGATTGGGAAATTGACCCTGAAGGCTTGAGAATTGCACTTCGTCGTATCACTTCTCGTTATCGTATTC
CAGTGATGATTACAGAAAATGGCTTGGGCGAATATGATAAAGTTGAAGACGGAAAAATTCATGATGATTATCGAATCAAA
TATCTAGAAAGTCATGTTAAAGCAATCAAAGAAGCGATGACGGATGGAGCAAAAGTCATTGGTTATCACACTTGGTCTTA
TACTGACCTCCTTTCTTGGTTAAATGGCTACCAAAAACGTTATGGCTTTGTCTATGTTGACCAAGATGAAACAATGGAAG
GTTCATTGAAACGGATACCGAAGGATTCTTATTACTGGTATCAACATCTCATCGAAACAAATGCTGAAGAAGTCTAA

Upstream 100 bases:

>100_bases
AATCACGTAAAAATAAAAAAACAAATTCCAAAAGATAAAACAAAATAAAACGGTTACAAATGTTATAATATAGACTATAA
ACAAGTAATGGGGGAATAAA

Downstream 100 bases:

>100_bases
ATGAAAAGCGCTCTCTGAGTGCTTTTTTTATGATATAATAGAAAAAAACAAATGAGGTAAGAGATGAAAATTCGTGGATT
TGAAGTGGTAACTAAATATA

Product: beta-glucosidase A

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MEHKKLKAFPNDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDHYHRYKEDVALMKELGLKSYR
FSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANEIEPIVTIYHWDLPQALEDLYGGWESREIIADFVNYAEVLFNAFKG
KVKYWVSLNEQNIFTSQGWSLATHPPGKRDMKLFYQVNHIANLTNAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINYYQTATNAWNPVDGGVGVGSF
NTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGLRIALRRITSRYRIPVMITENGLGEYDKVEDGKIHDDYRIK
YLESHVKAIKEAMTDGAKVIGYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNAEEV

Sequences:

>Translated_478_residues
MEHKKLKAFPNDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDHYHRYKEDVALMKELGLKSYR
FSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANEIEPIVTIYHWDLPQALEDLYGGWESREIIADFVNYAEVLFNAFKG
KVKYWVSLNEQNIFTSQGWSLATHPPGKRDMKLFYQVNHIANLTNAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINYYQTATNAWNPVDGGVGVGSF
NTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGLRIALRRITSRYRIPVMITENGLGEYDKVEDGKIHDDYRIK
YLESHVKAIKEAMTDGAKVIGYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNAEEV
>Mature_478_residues
MEHKKLKAFPNDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDHYHRYKEDVALMKELGLKSYR
FSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANEIEPIVTIYHWDLPQALEDLYGGWESREIIADFVNYAEVLFNAFKG
KVKYWVSLNEQNIFTSQGWSLATHPPGKRDMKLFYQVNHIANLTNAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINYYQTATNAWNPVDGGVGVGSF
NTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGLRIALRRITSRYRIPVMITENGLGEYDKVEDGKIHDDYRIK
YLESHVKAIKEAMTDGAKVIGYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNAEEV

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=483, Percent_Identity=33.7474120082816, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI110681710, Length=485, Percent_Identity=31.9587628865979, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI13273313, Length=489, Percent_Identity=32.3108384458078, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI24497614, Length=498, Percent_Identity=30.5220883534137, Blast_Score=186, Evalue=6e-47,
Organism=Homo sapiens, GI28376633, Length=478, Percent_Identity=29.7071129707113, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI190360571, Length=98, Percent_Identity=47.9591836734694, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI2367174, Length=503, Percent_Identity=36.9781312127237, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1789070, Length=496, Percent_Identity=35.8870967741936, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI2367270, Length=485, Percent_Identity=38.1443298969072, Blast_Score=291, Evalue=8e-80,
Organism=Caenorhabditis elegans, GI17552856, Length=487, Percent_Identity=29.9794661190965, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17539390, Length=486, Percent_Identity=30.4526748971193, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI21356577, Length=499, Percent_Identity=31.4629258517034, Blast_Score=216, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54721; Mature: 54721

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKKLKAFPNDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDH
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEHHH
YHRYKEDVALMKELGLKSYRFSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANEIEPIV
HHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
TIYHWDLPQALEDLYGGWESREIIADFVNYAEVLFNAFKGKVKYWVSLNEQNIFTSQGWS
EEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCE
LATHPPGKRDMKLFYQVNHIANLTNAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
ECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEE
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINY
EECCCHHHHHHHHEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEECEE
YQTATNAWNPVDGGVGVGSFNTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGL
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEECCHHH
RIALRRITSRYRIPVMITENGLGEYDKVEDGKIHDDYRIKYLESHVKAIKEAMTDGAKVI
HHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
GYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNAEEV
EEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEHKKLKAFPNDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDH
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEHHH
YHRYKEDVALMKELGLKSYRFSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANEIEPIV
HHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
TIYHWDLPQALEDLYGGWESREIIADFVNYAEVLFNAFKGKVKYWVSLNEQNIFTSQGWS
EEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCE
LATHPPGKRDMKLFYQVNHIANLTNAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
ECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEE
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINY
EECCCHHHHHHHHEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEECEE
YQTATNAWNPVDGGVGVGSFNTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGL
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEECCHHH
RIALRRITSRYRIPVMITENGLGEYDKVEDGKIHDDYRIKYLESHVKAIKEAMTDGAKVI
HHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
GYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNAEEV
EEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]