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The map label for this gene is ybbA

Identifier: 15672090

GI number: 15672090

Start: 110576

End: 111031

Strand: Direct

Name: ybbA

Synonym: L110564

Alternate gene names: 15672090

Gene position: 110576-111031 (Clockwise)

Preceding gene: 15672088

Following gene: 15672091

Centisome position: 4.67

GC content: 35.53

Gene sequence:

>456_bases
ATGAAAATAGTAATTCAACGTGTAAAGTCAGCTTCTGTCAGTATTGATGGAGTCATTAAGGGAAAAATTAATCAAGGATT
TTTATTGTTGGTTGGGGTTGAAGATGCTGACAGTAATTTTGATTTGGATTATGCAGTACGTAAAATCGCGCAAATGCGAA
TTTTTTCAGATGAAGCTGATAAAATGAATCTCTCTGTTCAAGATATTCAAGGAGAGATTTTGTCAATTTCTCAGTTTACT
TTGTATGCGGAGACTAAAAAAGGGAATCGTCCGAGCTTTTCGGCAGCAGGAAAACCTGATTTTGCTAAAGCAATGTATGA
AAAATTTAATGATAGCTTAGCTCAGATTGTGCCGGTTAAAGCAGGAGTTTTTGGGGCTGATATGCAAGTTGAGTTGATAA
ATGATGGCCCTGTCACTATTATTTTAGATACGAAAGAAGCTAGAAAAAATGCCTAA

Upstream 100 bases:

>100_bases
TATTAAAATGAATAAATGCCCAAAGAGAGCTGATTAAAATTGGACTTTTTGTGCTATACTGTCAGTAAAGAGATTATCAT
AGGAGTGAAATATAAAGATT

Downstream 100 bases:

>100_bases
AAGACTGCAAAAAAGTAGCGTAAAAAAATGGGTTCCTGTTCGCTCTGTCAGTAAAATAAAAACTTATCAGTCCTCAGAAA
AACCTGACCAAGTTGGTGAA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKIVIQRVKSASVSIDGVIKGKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEADKMNLSVQDIQGEILSISQFT
LYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVKAGVFGADMQVELINDGPVTIILDTKEARKNA

Sequences:

>Translated_151_residues
MKIVIQRVKSASVSIDGVIKGKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEADKMNLSVQDIQGEILSISQFT
LYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVKAGVFGADMQVELINDGPVTIILDTKEARKNA
>Mature_151_residues
MKIVIQRVKSASVSIDGVIKGKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEADKMNLSVQDIQGEILSISQFT
LYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVKAGVFGADMQVELINDGPVTIILDTKEARKNA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=43.2432432432432, Blast_Score=106, Evalue=7e-24,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=46.1538461538462, Blast_Score=127, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=39.3333333333333, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=45.2702702702703, Blast_Score=121, Evalue=4e-29,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=43.7086092715232, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_LACLA (Q9CJ92)

Other databases:

- EMBL:   AE005176
- PIR:   D86638
- RefSeq:   NP_266264.1
- ProteinModelPortal:   Q9CJ92
- SMR:   Q9CJ92
- GeneID:   1113714
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L110564
- NMPDR:   fig|272623.1.peg.115
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   LLAC272623:L110564-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16532; Mature: 16532

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIQRVKSASVSIDGVIKGKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEAD
CHHEEEECCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
KMNLSVQDIQGEILSISQFTLYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVK
CEEEEHHHCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEC
AGVFGADMQVELINDGPVTIILDTKEARKNA
CCEECCCEEEEEECCCCEEEEEECHHHCCCC
>Mature Secondary Structure
MKIVIQRVKSASVSIDGVIKGKINQGFLLLVGVEDADSNFDLDYAVRKIAQMRIFSDEAD
CHHEEEECCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
KMNLSVQDIQGEILSISQFTLYAETKKGNRPSFSAAGKPDFAKAMYEKFNDSLAQIVPVK
CEEEEHHHCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEC
AGVFGADMQVELINDGPVTIILDTKEARKNA
CCEECCCEEEEEECCCCEEEEEECHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471