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The map label for this gene is prmA

Identifier: 15672085

GI number: 15672085

Start: 104221

End: 105174

Strand: Direct

Name: prmA

Synonym: L104221

Alternate gene names: 15672085

Gene position: 104221-105174 (Clockwise)

Preceding gene: 15672084

Following gene: 15672086

Centisome position: 4.41

GC content: 40.67

Gene sequence:

>954_bases
ATGAATAATTGGAATTCAATCACAATAAAAATCAGTCGGGAAGCCGGAGAGGCCATTTCAGCTTTGCTGATAGAGGCGGG
GTCAGCCGGCGTTGAAATTAATGACAGTGCTGATTATCTCAATCACGAAGACCAATTTGGCGAAGTTCTTCCTGAAATTG
AACAATCTGATTTTGTTGAAATTACTGCTTATTATCCAGAAAATATGCCAATTGTGGAACTCAAAGCCGAAATCGAACAT
AAAATCGCAAATTTGAGTGATTATTTTTCGCTGACAGGTCTGTCAGTAACAACGAATAACCTGTCAGAAACAAATTGGGC
AGAAGCTTGGAAAAAATATTTTGAACCAGCACGAATTACGCATGATTTAACCATTGTGCCGAGTTGGACAGAGGATTACG
TGGCGACAGGCTCTGAAAAATTGATTCGACTTGACCCTGGTATGGCTTTTGGGACTGGAACACATCCAACGACCAAAATG
TCACTCTATGCCTTAGAACAAGTTCTTCGTGGTGGAGAAACGTTACTTGACGTTGGAACAGGTTCGGGTGTGCTGTCAGT
TGCAGCTTCATATCTTGGCGCAGCAGAAATATTTGCTTATGATATTGATGAAGTGGCTGTGCGCGTGGCTTTAGAAAATA
TTGAACTCAATCCTGGTCATGAAAAAATTCATGTTTCAGCAAACAATCTGCTTGAAGGAATTGACAAAAAAGCGGATGTC
ATTGTGGCTAATATTTTGGCTGATATCCTTGTTTTAATGACAGAAGACGCATTCCGCTTGGTCAAAGAAGAAGGCTATCT
CATTATGTCAGGAATTATTGCTGACAAAGCGGACATGGTCATTGCATCAGCAGAAAAAGCTGGATTTTTCCTTGAAACAC
GAATGATTCAAGGCGAATGGAACTGCCTGATTTTCAAGAAAACAGAAAATCGTGAAGGCGTCATTGGTGGATAA

Upstream 100 bases:

>100_bases
AAGAAGCTATCGAGCGAAATGTTAGGCGAGCGATTGGTTTCTTACTGGGAAAGAACTCTTTTGTAGGCCGAGATAAACCA
TAGAAAGAAAGATGAAATAA

Downstream 100 bases:

>100_bases
AAGGCTTAAATAAAGTCGTTTATCTTTCAGTCAATGGAGAAGCACAATAAAGAAAAGATTAGATTCAAAACTTTATTCTA
AGAAATGATTGGAAAAAATA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNNWNSITIKISREAGEAISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSDFVEITAYYPENMPIVELKAEIEH
KIANLSDYFSLTGLSVTTNNLSETNWAEAWKKYFEPARITHDLTIVPSWTEDYVATGSEKLIRLDPGMAFGTGTHPTTKM
SLYALEQVLRGGETLLDVGTGSGVLSVAASYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
IVANILADILVLMTEDAFRLVKEEGYLIMSGIIADKADMVIASAEKAGFFLETRMIQGEWNCLIFKKTENREGVIGG

Sequences:

>Translated_317_residues
MNNWNSITIKISREAGEAISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSDFVEITAYYPENMPIVELKAEIEH
KIANLSDYFSLTGLSVTTNNLSETNWAEAWKKYFEPARITHDLTIVPSWTEDYVATGSEKLIRLDPGMAFGTGTHPTTKM
SLYALEQVLRGGETLLDVGTGSGVLSVAASYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
IVANILADILVLMTEDAFRLVKEEGYLIMSGIIADKADMVIASAEKAGFFLETRMIQGEWNCLIFKKTENREGVIGG
>Mature_317_residues
MNNWNSITIKISREAGEAISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSDFVEITAYYPENMPIVELKAEIEH
KIANLSDYFSLTGLSVTTNNLSETNWAEAWKKYFEPARITHDLTIVPSWTEDYVATGSEKLIRLDPGMAFGTGTHPTTKM
SLYALEQVLRGGETLLDVGTGSGVLSVAASYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
IVANILADILVLMTEDAFRLVKEEGYLIMSGIIADKADMVIASAEKAGFFLETRMIQGEWNCLIFKKTENREGVIGG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=256, Percent_Identity=32.8125, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_LACLA (Q9CJ97)

Other databases:

- EMBL:   AE005176
- PIR:   G86637
- RefSeq:   NP_266259.1
- ProteinModelPortal:   Q9CJ97
- GeneID:   1113709
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L104221
- NMPDR:   fig|272623.1.peg.110
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   PRK00517
- BioCyc:   LLAC272623:L104221-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34754; Mature: 34754

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNWNSITIKISREAGEAISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSDFVE
CCCCEEEEEEEECCHHHHHHHHHHCCCCCCEEECCCHHHCCCCHHHHHHHCCCCCCCEEE
ITAYYPENMPIVELKAEIEHKIANLSDYFSLTGLSVTTNNLSETNWAEAWKKYFEPARIT
EEEECCCCCCEEEEHHHHHHHHHCHHHHHEEECEEEEECCCCCCHHHHHHHHHCCCCCEE
HDLTIVPSWTEDYVATGSEKLIRLDPGMAFGTGTHPTTKMSLYALEQVLRGGETLLDVGT
EEEEEECCCCHHHHHCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECC
GSGVLSVAASYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
CCHHHHHHHHHHCHHHHEEECHHHHHEEEEEEEEEECCCCCEEEEEHHHHHHHCCCHHHH
IVANILADILVLMTEDAFRLVKEEGYLIMSGIIADKADMVIASAEKAGFFLETRMIQGEW
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCEEEEEEEECCCC
NCLIFKKTENREGVIGG
EEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNNWNSITIKISREAGEAISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSDFVE
CCCCEEEEEEEECCHHHHHHHHHHCCCCCCEEECCCHHHCCCCHHHHHHHCCCCCCCEEE
ITAYYPENMPIVELKAEIEHKIANLSDYFSLTGLSVTTNNLSETNWAEAWKKYFEPARIT
EEEECCCCCCEEEEHHHHHHHHHCHHHHHEEECEEEEECCCCCCHHHHHHHHHCCCCCEE
HDLTIVPSWTEDYVATGSEKLIRLDPGMAFGTGTHPTTKMSLYALEQVLRGGETLLDVGT
EEEEEECCCCHHHHHCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECC
GSGVLSVAASYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
CCHHHHHHHHHHCHHHHEEECHHHHHEEEEEEEEEECCCCCEEEEEHHHHHHHCCCHHHH
IVANILADILVLMTEDAFRLVKEEGYLIMSGIIADKADMVIASAEKAGFFLETRMIQGEW
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCEEEEEEEECCCC
NCLIFKKTENREGVIGG
EEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471