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The map label for this gene is fabZ

Identifier: 15835433

GI number: 15835433

Start: 951885

End: 952346

Strand: Reverse

Name: fabZ

Synonym: TC0819

Alternate gene names: 15835433

Gene position: 952346-951885 (Counterclockwise)

Preceding gene: 15835434

Following gene: 15835432

Centisome position: 88.76

GC content: 39.18

Gene sequence:

>462_bases
ATGAGTGAAAAGCCTGTATTAGGAATCCAAGATATACAAAATTTGCTTCCACACCGATATCCCTTCCTATTAGTGGATAA
AATTCTTTCTTATGATTTAAATACCCGTTCGATAGTGGCCCAGAAAAATGTAACCATTAACGAACCTTTTTTCGTAGGAC
ATTTCCCTGAGGCACCTATCATGCCTGGAGTTTTGATATTAGAAGCTCTGGCCCAAGCTGCTGGTGTGTTGCTAGGAATT
ATATTGGAAAATGATCGAGATAAAAAGATCGCATTATTCTTAGGTATCCAGAAGGCAAAATTTCGTCAGCCCGTCAAGCC
TGGGGATGTATTGATCTTGAAAGCAGAATTCTCGTTGATATCAGCTAAAGGAGGGAAGGCTATAGCACAAGCTTTTGTCG
GTTCTCAGATTGTAGCTGAAGGAGAGCTTAGCTTTGTTCTTGTTAAAAAAGAGTCTATATAA

Upstream 100 bases:

>100_bases
TTTTAGCACACATTATAGCTGTGGGGTCAGGGCATTCTTCTAATATTGCCTTAGGGAATAAAATTTTAGAGGCGTTGCAG
TATGAACAGGAGTTAGTAAA

Downstream 100 bases:

>100_bases
AGAGGCAGAGTATGACCAACATTCATCCTACAGCTATTGTGGAAGATGGGGCGCAGATTGGAAATAATGTAACTATAGAG
CCCTATGCTATTGTAAAAAA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MSEKPVLGIQDIQNLLPHRYPFLLVDKILSYDLNTRSIVAQKNVTINEPFFVGHFPEAPIMPGVLILEALAQAAGVLLGI
ILENDRDKKIALFLGIQKAKFRQPVKPGDVLILKAEFSLISAKGGKAIAQAFVGSQIVAEGELSFVLVKKESI

Sequences:

>Translated_153_residues
MSEKPVLGIQDIQNLLPHRYPFLLVDKILSYDLNTRSIVAQKNVTINEPFFVGHFPEAPIMPGVLILEALAQAAGVLLGI
ILENDRDKKIALFLGIQKAKFRQPVKPGDVLILKAEFSLISAKGGKAIAQAFVGSQIVAEGELSFVLVKKESI
>Mature_152_residues
SEKPVLGIQDIQNLLPHRYPFLLVDKILSYDLNTRSIVAQKNVTINEPFFVGHFPEAPIMPGVLILEALAQAAGVLLGII
LENDRDKKIALFLGIQKAKFRQPVKPGDVLILKAEFSLISAKGGKAIAQAFVGSQIVAEGELSFVLVKKESI

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=43.4782608695652, Blast_Score=115, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_CHLMU (Q9PJL0)

Other databases:

- EMBL:   AE002160
- PIR:   H81661
- RefSeq:   NP_297192.1
- ProteinModelPortal:   Q9PJL0
- SMR:   Q9PJL0
- GeneID:   1246186
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0819
- TIGR:   TC_0819
- HOGENOM:   HBG433282
- OMA:   MANIHRM
- ProtClustDB:   PRK00006
- BioCyc:   CMUR243161:TC_0819-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16703; Mature: 16572

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: ACT_SITE 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKPVLGIQDIQNLLPHRYPFLLVDKILSYDLNTRSIVAQKNVTINEPFFVGHFPEAPI
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCEECCCEEEECCCCCCC
MPGVLILEALAQAAGVLLGIILENDRDKKIALFLGIQKAKFRQPVKPGDVLILKAEFSLI
CCHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCHHHHCCCCCCCCEEEEEECEEEE
SAKGGKAIAQAFVGSQIVAEGELSFVLVKKESI
ECCCCHHHHHHHHCCEEEECCCEEEEEEEECCC
>Mature Secondary Structure 
SEKPVLGIQDIQNLLPHRYPFLLVDKILSYDLNTRSIVAQKNVTINEPFFVGHFPEAPI
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCEECCCEEEECCCCCCC
MPGVLILEALAQAAGVLLGIILENDRDKKIALFLGIQKAKFRQPVKPGDVLILKAEFSLI
CCHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCHHHHCCCCCCCCEEEEEECEEEE
SAKGGKAIAQAFVGSQIVAEGELSFVLVKKESI
ECCCCHHHHHHHHCCEEEECCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935