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The map label for this gene is accD

Identifier: 15835183

GI number: 15835183

Start: 676565

End: 677416

Strand: Reverse

Name: accD

Synonym: TC0566

Alternate gene names: 15835183

Gene position: 677416-676565 (Counterclockwise)

Preceding gene: 15835184

Following gene: 161579045

Centisome position: 63.14

GC content: 41.78

Gene sequence:

>852_bases
GTGCGTTTATTTTCTTATGATAAACCAAAGATCAAAGTGCAAAAAATAAAGACCGATAGTTTCAATGGCTGGCTAAAATG
TACGCATTGTAGCGAGATGATCCATGCTAATGAGTTAGGGCAGAACTTTAATTGCTGCCCTAAGTGTTCTTACCACTACC
GCATTAGTGCTTCAGAGCGGATAGCTCTGTTGGCTGATGAAGGTTCTTGGAATCCTTTGTTCTCAGAATTAAAATCTCAA
GATCCTTTGCATTTTGTTGACACAGATACCTATTCTAATCGCTTAGAGAAAGCTCGAAAAAATAATCCTGATAGCGAAGG
AGTTTTAGTAGGGAACTGTACGATTGGAGGGCATTCCGTCGCTCTGGCCGTTATGGATTTCAGCTTTATGGCAGGTTCCA
TGGGTGCAGTTGTTGGAGAGAAATTGACTCGTTTAATAGAGAAAGCTATAGATTCTAGATGGCCTGTGATTATTGTTTCT
GCTTCGGGAGGAGCTAGGATGCAAGAATCTGTATTCTCCCTAATGCAAATGGCCAAAACCTCCGCTGCTTTGGCCAAATT
ACATGAAGCCAAGCTTCCTTATATTTCTGTTTTGACCAACCCTACTTCTGGAGGAGTCACTGCCTCATTTGCTTCCTTGG
GAGATGTCATTATTGCAGAACCTAAGGCTCTTATTTGCTTCGCAGGGCCACGAGTGGTTTCTCAAGTAATAGGAGAAGAT
CTTCCAGAAGGAGCTCAGAAGTCTGAGTTTTTATTGGAGCATGGGATGATCGATAAGGTCGTGGAGAGAAAACAGCTCAA
AGCAACTTTGGAAAGCTTGTTAAATTTTTTCAATTGTCAGGCGTATTCCTAA

Upstream 100 bases:

>100_bases
AGTCGTTTTGTAGAAATGAGTAAGTAATAATTTTATTATTGATTGGTTAAGAAGAATTAAAATAAAATTATTGCTCAATT
TTTTGTAAAGAGGATGGTTT

Downstream 100 bases:

>100_bases
GGGCAAGACAAATCCTCTAGAAGTAGCTCTAAGACCTTTTAGGGGATTTTTTTTGTTGACAGATGACAAGCGAATAAAAG
ATCATGGGCGGCTCTTCAAA

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MRLFSYDKPKIKVQKIKTDSFNGWLKCTHCSEMIHANELGQNFNCCPKCSYHYRISASERIALLADEGSWNPLFSELKSQ
DPLHFVDTDTYSNRLEKARKNNPDSEGVLVGNCTIGGHSVALAVMDFSFMAGSMGAVVGEKLTRLIEKAIDSRWPVIIVS
ASGGARMQESVFSLMQMAKTSAALAKLHEAKLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVSQVIGED
LPEGAQKSEFLLEHGMIDKVVERKQLKATLESLLNFFNCQAYS

Sequences:

>Translated_283_residues
MRLFSYDKPKIKVQKIKTDSFNGWLKCTHCSEMIHANELGQNFNCCPKCSYHYRISASERIALLADEGSWNPLFSELKSQ
DPLHFVDTDTYSNRLEKARKNNPDSEGVLVGNCTIGGHSVALAVMDFSFMAGSMGAVVGEKLTRLIEKAIDSRWPVIIVS
ASGGARMQESVFSLMQMAKTSAALAKLHEAKLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVSQVIGED
LPEGAQKSEFLLEHGMIDKVVERKQLKATLESLLNFFNCQAYS
>Mature_283_residues
MRLFSYDKPKIKVQKIKTDSFNGWLKCTHCSEMIHANELGQNFNCCPKCSYHYRISASERIALLADEGSWNPLFSELKSQ
DPLHFVDTDTYSNRLEKARKNNPDSEGVLVGNCTIGGHSVALAVMDFSFMAGSMGAVVGEKLTRLIEKAIDSRWPVIIVS
ASGGARMQESVFSLMQMAKTSAALAKLHEAKLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVSQVIGED
LPEGAQKSEFLLEHGMIDKVVERKQLKATLESLLNFFNCQAYS

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=230, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1788655, Length=251, Percent_Identity=52.191235059761, Blast_Score=268, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI25147362, Length=233, Percent_Identity=26.6094420600858, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147359, Length=233, Percent_Identity=26.6094420600858, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 31017; Mature: 31017

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFSYDKPKIKVQKIKTDSFNGWLKCTHCSEMIHANELGQNFNCCPKCSYHYRISASER
CCCCCCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCE
IALLADEGSWNPLFSELKSQDPLHFVDTDTYSNRLEKARKNNPDSEGVLVGNCTIGGHSV
EEEEECCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEEEEEECCHHH
ALAVMDFSFMAGSMGAVVGEKLTRLIEKAIDSRWPVIIVSASGGARMQESVFSLMQMAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SAALAKLHEAKLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVSQVIGED
HHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHCCEEEECCCEEEEECCHHHHHHHHHCC
LPEGAQKSEFLLEHGMIDKVVERKQLKATLESLLNFFNCQAYS
CCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRLFSYDKPKIKVQKIKTDSFNGWLKCTHCSEMIHANELGQNFNCCPKCSYHYRISASER
CCCCCCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCE
IALLADEGSWNPLFSELKSQDPLHFVDTDTYSNRLEKARKNNPDSEGVLVGNCTIGGHSV
EEEEECCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEEEEEECCHHH
ALAVMDFSFMAGSMGAVVGEKLTRLIEKAIDSRWPVIIVSASGGARMQESVFSLMQMAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SAALAKLHEAKLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVSQVIGED
HHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHCCEEEECCCEEEEECCHHHHHHHHHCC
LPEGAQKSEFLLEHGMIDKVVERKQLKATLESLLNFFNCQAYS
CCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA