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The map label for this gene is accA

Identifier: 15835154

GI number: 15835154

Start: 646545

End: 647519

Strand: Reverse

Name: accA

Synonym: TC0536

Alternate gene names: 15835154

Gene position: 647519-646545 (Counterclockwise)

Preceding gene: 15835155

Following gene: 15835153

Centisome position: 60.35

GC content: 41.23

Gene sequence:

>975_bases
GTGGAACTACTTCCTCATGAAAAACAGGTTGTCGAATACGAAAAAACGATCGCCGATTTCAAAGAAAAAAATAAAGAAAA
CAGTCTGCTTTCTTCTTCAGAGATTCAAAAATTGGAAAATCGCTTAGATAGACTAAAAGAAAAAATTTATTCGAATCTTA
CTCCTTGGGAAAGGGTACAAATTTGCCGACACCCTTCGAGACCCCGCACGATTAATTATATTGAAGGGATGTGTGAAGAG
TTTGTTGAGCTTTGTGGAGATCGAACATTCCGTGATGATCCTGCAGTTGTCGGAGGATTTGCAAAGATTCAGGGACAACG
GTTTATGCTCATAGGGCAAGAAAAAGGTTGTGATACGACATCTCGTATGCATCGCAATTTTGGAATGCTTTGTCCTGAAG
GATTTCGGAAAGCTTTGCGCTTAGCTAAAATGGCTGAAAAATTTGGTCTTCCTATTATCTTCTTAGTGGACACCCCAGGG
GCTTTCCCAGGACTAACAGCTGAAGAGCGTGGGCAGGGGTGGGCTATTGCAACGAATTTGTTTGAGCTTGCCAGATTAGC
TACTCCAATTATCGTAGTTGTTATTGGAGAAGGATGTTCAGGAGGAGCTTTAGGGATGGCTATAGGAGATGTTGTAGCAA
TGCTAGAACATTCTTATTATTCCGTAATTTCTCCCGAAGGATGTGCTTCTATTTTGTGGAAAGATCCCAAAAAAAATAGC
GATGCCGCAGCCATGTTAAAAATGCATGGAGAGGATCTTAAAGGATTTGCTATTGTAGACGCAGTGATTAAAGAGCCCAT
AGGTGGGGCGCATCACAATCCTGTGGCTACATATCGTAGTGTTCAAGAATATGTCCTGCAAGAATGGCTTAAATTGAAAG
ATCTACCGGTAGAAGAGTTGCTAGAGAAACGATACCAGAAATTCCGAACGATAGGTCTATATGAAACTTCTTCTGAAAGC
AGTTCTGAGGCATAA

Upstream 100 bases:

>100_bases
TGAAACAAGGGATGTTATAATCAACTAGTTGGTTTTTGGTTGTTTTTGATAATTATTTGTATTAAAATAACTCTTTTTTA
TAAGAAGGGAGCGTGCTACG

Downstream 100 bases:

>100_bases
AAAGCATTTAGTTCTGCTCGGTTTTTCTCTTTTATCCATATTAGGACTGACGATAACGTCTCAAGCAGAAATTTTTTCTT
TGGGACTTATCGCTAAGACT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MELLPHEKQVVEYEKTIADFKEKNKENSLLSSSEIQKLENRLDRLKEKIYSNLTPWERVQICRHPSRPRTINYIEGMCEE
FVELCGDRTFRDDPAVVGGFAKIQGQRFMLIGQEKGCDTTSRMHRNFGMLCPEGFRKALRLAKMAEKFGLPIIFLVDTPG
AFPGLTAEERGQGWAIATNLFELARLATPIIVVVIGEGCSGGALGMAIGDVVAMLEHSYYSVISPEGCASILWKDPKKNS
DAAAMLKMHGEDLKGFAIVDAVIKEPIGGAHHNPVATYRSVQEYVLQEWLKLKDLPVEELLEKRYQKFRTIGLYETSSES
SSEA

Sequences:

>Translated_324_residues
MELLPHEKQVVEYEKTIADFKEKNKENSLLSSSEIQKLENRLDRLKEKIYSNLTPWERVQICRHPSRPRTINYIEGMCEE
FVELCGDRTFRDDPAVVGGFAKIQGQRFMLIGQEKGCDTTSRMHRNFGMLCPEGFRKALRLAKMAEKFGLPIIFLVDTPG
AFPGLTAEERGQGWAIATNLFELARLATPIIVVVIGEGCSGGALGMAIGDVVAMLEHSYYSVISPEGCASILWKDPKKNS
DAAAMLKMHGEDLKGFAIVDAVIKEPIGGAHHNPVATYRSVQEYVLQEWLKLKDLPVEELLEKRYQKFRTIGLYETSSES
SSEA
>Mature_324_residues
MELLPHEKQVVEYEKTIADFKEKNKENSLLSSSEIQKLENRLDRLKEKIYSNLTPWERVQICRHPSRPRTINYIEGMCEE
FVELCGDRTFRDDPAVVGGFAKIQGQRFMLIGQEKGCDTTSRMHRNFGMLCPEGFRKALRLAKMAEKFGLPIIFLVDTPG
AFPGLTAEERGQGWAIATNLFELARLATPIIVVVIGEGCSGGALGMAIGDVVAMLEHSYYSVISPEGCASILWKDPKKNS
DAAAMLKMHGEDLKGFAIVDAVIKEPIGGAHHNPVATYRSVQEYVLQEWLKLKDLPVEELLEKRYQKFRTIGLYETSSES
SSEA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=315, Percent_Identity=45.0793650793651, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_CHLMU (Q9PKC9)

Other databases:

- EMBL:   AE002160
- PIR:   D81691
- RefSeq:   NP_296913.1
- ProteinModelPortal:   Q9PKC9
- SMR:   Q9PKC9
- GeneID:   1245896
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0536
- TIGR:   TC_0536
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q9PKC9
- ProtClustDB:   PRK05724
- BioCyc:   CMUR243161:TC_0536-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36346; Mature: 36346

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLPHEKQVVEYEKTIADFKEKNKENSLLSSSEIQKLENRLDRLKEKIYSNLTPWERVQ
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ICRHPSRPRTINYIEGMCEEFVELCGDRTFRDDPAVVGGFAKIQGQRFMLIGQEKGCDTT
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCHHHHHCCCEEEEEECCCCCCHH
SRMHRNFGMLCPEGFRKALRLAKMAEKFGLPIIFLVDTPGAFPGLTAEERGQGWAIATNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCCHHHHHH
FELARLATPIIVVVIGEGCSGGALGMAIGDVVAMLEHSYYSVISPEGCASILWKDPKKNS
HHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
DAAAMLKMHGEDLKGFAIVDAVIKEPIGGAHHNPVATYRSVQEYVLQEWLKLKDLPVEEL
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
LEKRYQKFRTIGLYETSSESSSEA
HHHHHHHHHHHCCEECCCCCCCCC
>Mature Secondary Structure
MELLPHEKQVVEYEKTIADFKEKNKENSLLSSSEIQKLENRLDRLKEKIYSNLTPWERVQ
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ICRHPSRPRTINYIEGMCEEFVELCGDRTFRDDPAVVGGFAKIQGQRFMLIGQEKGCDTT
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCHHHHHCCCEEEEEECCCCCCHH
SRMHRNFGMLCPEGFRKALRLAKMAEKFGLPIIFLVDTPGAFPGLTAEERGQGWAIATNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCCHHHHHH
FELARLATPIIVVVIGEGCSGGALGMAIGDVVAMLEHSYYSVISPEGCASILWKDPKKNS
HHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
DAAAMLKMHGEDLKGFAIVDAVIKEPIGGAHHNPVATYRSVQEYVLQEWLKLKDLPVEEL
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
LEKRYQKFRTIGLYETSSESSSEA
HHHHHHHHHHHCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935