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The map label for this gene is rpiA

Identifier: 15835103

GI number: 15835103

Start: 589237

End: 589956

Strand: Reverse

Name: rpiA

Synonym: TC0485

Alternate gene names: 15835103

Gene position: 589956-589237 (Counterclockwise)

Preceding gene: 15835104

Following gene: 15835102

Centisome position: 54.98

GC content: 41.94

Gene sequence:

>720_bases
ATGTCTAAACAAGTAGCTCATTCTTTTTCTTCTGAAGATTTTTCCTTTATAAAACAAAAATTAGCGCGAGAGGCTGTGGC
TTTGGTAGAGCCTGGAATGCGTGTAGGATTGGGAAGTGGATCTACGGCCCGAGAATTTATTTTGGCCTTAGGGGAGCGTG
TTCGGAATGAGCGGCTAGCAATTACAGCTGTTGCCTCCTCAAGAATATCACATTTGTTAGCCCAAGCGTTAGGGATTCCT
TTTCTAGATCCTGCATTATCCCAGGAGTTAGATTTGGTTGTGGATGGGGCTGATGAAGTAGATGCTAATTTGCGTATGAT
TAAGGGGGGAGGAGGAGCTCTTTTCCGGGAAAAAATTCTTCTACAAAGTGGTAAACGAAATATTATTCTAGTAGATGAGC
GCAAGCTCGTTTCTGTATTAGGGACATTTCCTCTCCCTATCGAAATTTCTCCTTTTGGTTGTTCATCGGTGGAGAAAGTA
CTTAATCAACAAGGGTATATTGGAGATTGGCGTAAAACTTCTCACGGAGAACGTTTTATCACAGATAACGGCAATTATAT
CTATGATGTGAGCTCTCCAGATTCTTATCCTCATCCAGAAGAAGATCTGATTAGATTGTTACAAATTCGTGGCATTATTG
ATGTCGGGTTTGTTATAGCAAAGGCCGAGGTGTGGGTAGGTTACGCCGATGGTACTGTGGTTCGGAAAGAAATTACGTAA

Upstream 100 bases:

>100_bases
ATTAAGCCTTGATAAAGATTTGAATGAATCCTAAATAAATTGTAGGATTCCTTGTTTAAGGAAGGGAACAGATCCCTTCC
TAGGTTGTTTCGAGAGGCTT

Downstream 100 bases:

>100_bases
TGAATATTGATCGAGAAATCATAAAAGATACTTCACTAATCTTAATAAGCTTTCATAAATTAGTAAATTTCCATAATTAT
GCAGGCATTATTTTGGGGAC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSKQVAHSFSSEDFSFIKQKLAREAVALVEPGMRVGLGSGSTAREFILALGERVRNERLAITAVASSRISHLLAQALGIP
FLDPALSQELDLVVDGADEVDANLRMIKGGGGALFREKILLQSGKRNIILVDERKLVSVLGTFPLPIEISPFGCSSVEKV
LNQQGYIGDWRKTSHGERFITDNGNYIYDVSSPDSYPHPEEDLIRLLQIRGIIDVGFVIAKAEVWVGYADGTVVRKEIT

Sequences:

>Translated_239_residues
MSKQVAHSFSSEDFSFIKQKLAREAVALVEPGMRVGLGSGSTAREFILALGERVRNERLAITAVASSRISHLLAQALGIP
FLDPALSQELDLVVDGADEVDANLRMIKGGGGALFREKILLQSGKRNIILVDERKLVSVLGTFPLPIEISPFGCSSVEKV
LNQQGYIGDWRKTSHGERFITDNGNYIYDVSSPDSYPHPEEDLIRLLQIRGIIDVGFVIAKAEVWVGYADGTVVRKEIT
>Mature_238_residues
SKQVAHSFSSEDFSFIKQKLAREAVALVEPGMRVGLGSGSTAREFILALGERVRNERLAITAVASSRISHLLAQALGIPF
LDPALSQELDLVVDGADEVDANLRMIKGGGGALFREKILLQSGKRNIILVDERKLVSVLGTFPLPIEISPFGCSSVEKVL
NQQGYIGDWRKTSHGERFITDNGNYIYDVSSPDSYPHPEEDLIRLLQIRGIIDVGFVIAKAEVWVGYADGTVVRKEIT

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=209, Percent_Identity=34.4497607655502, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1789280, Length=224, Percent_Identity=37.9464285714286, Blast_Score=114, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17551758, Length=238, Percent_Identity=33.1932773109244, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324669, Length=216, Percent_Identity=32.4074074074074, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281364072, Length=211, Percent_Identity=29.3838862559242, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_CHLMU (Q9PKI0)

Other databases:

- EMBL:   AE002160
- PIR:   E81697
- RefSeq:   NP_296862.1
- ProteinModelPortal:   Q9PKI0
- SMR:   Q9PKI0
- GeneID:   1245843
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0485
- TIGR:   TC_0485
- HOGENOM:   HBG515603
- OMA:   DKSIVGV
- PhylomeDB:   Q9PKI0
- ProtClustDB:   PRK00702
- BioCyc:   CMUR243161:TC_0485-MONOMER
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 26180; Mature: 26049

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQVAHSFSSEDFSFIKQKLAREAVALVEPGMRVGLGSGSTAREFILALGERVRNERLA
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCEE
ITAVASSRISHLLAQALGIPFLDPALSQELDLVVDGADEVDANLRMIKGGGGALFREKIL
EEEHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHH
LQSGKRNIILVDERKLVSVLGTFPLPIEISPFGCSSVEKVLNQQGYIGDWRKTSHGERFI
HHCCCCCEEEECCHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEE
TDNGNYIYDVSSPDSYPHPEEDLIRLLQIRGIIDVGFVIAKAEVWVGYADGTVVRKEIT
ECCCCEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHEEEEEEEEEEECCCEEEEEECC
>Mature Secondary Structure 
SKQVAHSFSSEDFSFIKQKLAREAVALVEPGMRVGLGSGSTAREFILALGERVRNERLA
CCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCEE
ITAVASSRISHLLAQALGIPFLDPALSQELDLVVDGADEVDANLRMIKGGGGALFREKIL
EEEHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHH
LQSGKRNIILVDERKLVSVLGTFPLPIEISPFGCSSVEKVLNQQGYIGDWRKTSHGERFI
HHCCCCCEEEECCHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCEEE
TDNGNYIYDVSSPDSYPHPEEDLIRLLQIRGIIDVGFVIAKAEVWVGYADGTVVRKEIT
ECCCCEEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHEEEEEEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935