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Identifier: 15835067

GI number: 15835067

Start: 547147

End: 547860

Strand: Reverse

Name: Not Available

Synonym: TC0449

Alternate gene names: 15835067

Gene position: 547860-547147 (Counterclockwise)

Preceding gene: 15835069

Following gene: 15835066

Centisome position: 51.06

GC content: 39.5

Gene sequence:

>714_bases
ATGAATCAGAGGATTCCTTTGAGGAAAAAGATCCTTATTATTGTTACAGCATTGGGATTTGTTTCATGCGTGGGCTTGAT
GGTGCAAACAAAACGCTCTATTATGCCGCCAAAAGCACATATACCCACCACAGCAAAATATTTTCCTACAATAGGGAATC
CTTATGCACCCATTAATATTACTGTGTTTGAAGAGCCTTCTTGTTCTGCGTGTGAGGAGTTTTCTTCAGAAGTCTTTCCT
TTGATCAAAAAACGCTTTATTGATACCGGGGAAGCCTCTTTCACTTTGATTCCGGTCTGTTTTATTAGAGGATCAATGCC
CGCTGCACAGGCTTTGCTTTGTGTCTATCATCATGATCCTAAACGACCTGATCCAGAAGCCTATATGGAGTATTTTCACA
GAATCCTTACTCATAAAAAAACAGAAGGATCACACTGGGCTACTACTGAAGTTCTTACGAAATTAGCAGAAAATATTCCT
ACGCATTCTGGTAGAGAAATTAATCCTACAGGGTTGATGCAATGTGTAAATTCGCAGAAATTTGCGGAACAGCTAAAAAA
GAACAATATTTATGGATCTCAAGTCATGGGTGGTCAACTTGCTACTCCCACAGCAATAGTGGGGGACTATCTTATTGAGG
ATCCAACGTTTGATGAAATTGAAAGAGTAATTACTCAACTGCGTCATTTACAAGCAATGGAAGAGGAGGAATAG

Upstream 100 bases:

>100_bases
GTTTTTTTTAATAGAAGTGCTTATAGAAACTTTTTCTATGTCAGCAAAAAACGGTTTCGTTTTTTTTAATTTTGTCTTAT
CTCAACTCCTATATGAAAGA

Downstream 100 bases:

>100_bases
TGATTAAACTCTTACGTTCTTATTGCTTATATTTTGCCTGGTTGGTTTCTTGTATAGGGACTCTCATGAGTGTCTATTAT
AGCTATCTACTCAATGTAGA

Product: hypothetical protein

Products: NA

Alternate protein names: Disulfide oxidoreductase D; Thiol-disulfide oxidoreductase D [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNQRIPLRKKILIIVTALGFVSCVGLMVQTKRSIMPPKAHIPTTAKYFPTIGNPYAPINITVFEEPSCSACEEFSSEVFP
LIKKRFIDTGEASFTLIPVCFIRGSMPAAQALLCVYHHDPKRPDPEAYMEYFHRILTHKKTEGSHWATTEVLTKLAENIP
THSGREINPTGLMQCVNSQKFAEQLKKNNIYGSQVMGGQLATPTAIVGDYLIEDPTFDEIERVITQLRHLQAMEEEE

Sequences:

>Translated_237_residues
MNQRIPLRKKILIIVTALGFVSCVGLMVQTKRSIMPPKAHIPTTAKYFPTIGNPYAPINITVFEEPSCSACEEFSSEVFP
LIKKRFIDTGEASFTLIPVCFIRGSMPAAQALLCVYHHDPKRPDPEAYMEYFHRILTHKKTEGSHWATTEVLTKLAENIP
THSGREINPTGLMQCVNSQKFAEQLKKNNIYGSQVMGGQLATPTAIVGDYLIEDPTFDEIERVITQLRHLQAMEEEE
>Mature_237_residues
MNQRIPLRKKILIIVTALGFVSCVGLMVQTKRSIMPPKAHIPTTAKYFPTIGNPYAPINITVFEEPSCSACEEFSSEVFP
LIKKRFIDTGEASFTLIPVCFIRGSMPAAQALLCVYHHDPKRPDPEAYMEYFHRILTHKKTEGSHWATTEVLTKLAENIP
THSGREINPTGLMQCVNSQKFAEQLKKNNIYGSQVMGGQLATPTAIVGDYLIEDPTFDEIERVITQLRHLQAMEEEE

Specific function: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26679; Mature: 26679

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRIPLRKKILIIVTALGFVSCVGLMVQTKRSIMPPKAHIPTTAKYFPTIGNPYAPINI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCEEE
TVFEEPSCSACEEFSSEVFPLIKKRFIDTGEASFTLIPVCFIRGSMPAAQALLCVYHHDP
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCC
KRPDPEAYMEYFHRILTHKKTEGSHWATTEVLTKLAENIPTHSGREINPTGLMQCVNSQK
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
FAEQLKKNNIYGSQVMGGQLATPTAIVGDYLIEDPTFDEIERVITQLRHLQAMEEEE
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQRIPLRKKILIIVTALGFVSCVGLMVQTKRSIMPPKAHIPTTAKYFPTIGNPYAPINI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCEEE
TVFEEPSCSACEEFSSEVFPLIKKRFIDTGEASFTLIPVCFIRGSMPAAQALLCVYHHDP
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCC
KRPDPEAYMEYFHRILTHKKTEGSHWATTEVLTKLAENIPTHSGREINPTGLMQCVNSQK
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
FAEQLKKNNIYGSQVMGGQLATPTAIVGDYLIEDPTFDEIERVITQLRHLQAMEEEE
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11844773; 11744713 [H]