Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15835040

GI number: 15835040

Start: 482348

End: 484192

Strand: Direct

Name: Not Available

Synonym: TC0422

Alternate gene names: 15835040

Gene position: 482348-484192 (Clockwise)

Preceding gene: 15835039

Following gene: 15835041

Centisome position: 44.96

GC content: 42.28

Gene sequence:

>1845_bases
ATGGAAGAGCAATCCACAGTTGAATATTGGGGAGATTACAAAGTTATCGCGGAACTCGAGCAAGGATTGTGGAGTCGAGA
TGTTCTTACAGAACATCGGTTTATTAAAAAACGTTACGTGCTCAAGATACTTCCTTCGGAACTTTCATTGTCAGAAGATT
TTATGAAAGTGTTTCAAAAGGTCATTGTTCAATTAGCTACGATTCGCCATCCAAGCTTGGTAGCTATTGAGAATGTTTCT
CAGGAGAAGGATCGCTATTTTATTGTGACGGAAGAGAATAGCGGTACGATCTCTCTGGCCAAGTATTTATCTGGAAGAAA
ACTATCAGAAGAAGAGATTGTGTATTTGATTCAACAACTTTGTGAAGTTTTGGAGCTAGTACATGAAATAGGATTAGCTC
ATGGTCAGATTAATTTACATTCTGTTCATGTCTCTTTTATCAATGGAGTAGCCAATATTTATCTTCCTGAGGTGGGGTTC
GCATCTTTGCTTAGAGAACGTATGTTCTCCTCTATTATGCAGAAAGCTTCCATGCAAGAAAGCGTGGAATGTATTCGTGA
TTTGTTGGTGTTTGAGGCTCCTGAAGAGAAATCAACCAATCACCGTGCGACAGATGCGTACTCAGTTGGTGTGTTAGCTT
ATTACTTGCTAGTAGGAGCATTTCCTTGGGGAGCTTTTCCTAAACCCTCGTCTTGTATACCTGACAGTATTTATGATTGG
GATAGTTTTATTTTGAGTTGTTTGCAGCAACAACAACAAGCCAGACCGAAGCGATTGCGAGATGCTCTAAAGAAAAAAAC
ATTAGGAGAGCAGCTCCAGTCGACTATTGACCACTGTCGTGAGTCCTTGCGTGCGATGGAAGTTCAAGAGGAGGTTTCGG
AACCTATTGCTCCGACGTCTCTGATTCGAGAGGGAGAGAAGCTTTTTGAGGGCAAAGAGGAACAACAAGCTTTTGTATTA
GTAGAGGCTAAATCGATTGATGAAGCAATGGTTACTACTGTGGATTCAGAGGAAGTATCGGAGAGTGGAGAAGGATATGT
CAATCCGTTGCAGTCTTTATTAGCAAGAGAACCGGTCGTTAGTCGCTACGTAGAAATAGAAAGAGAAGAAGTGAAACCTC
AACCGCTATCTACCGAAATGGTGTTTATTGAGGGAGGAGATTTTTCTCGTGGAAGCAGAGATGGACAGAGGGATGAATTA
CCGGTTCATAATATCACCCTTCCGGGATTTCTTTTAGATATTCATCCTGTTACGAATGAGCATTTTGTACGTTTTTTGGA
GTTTATTGGCGGAGAACAGGACGAACATTATAATGAACTAATTCGTTTAAAAGATTCTAGGATTCAGCGTCGCTCAGGCA
GGCTTATTATTGAGCCTGGATATGCTAAACATCCTGTTGTGGGTGTGACTTGGTATGGTGCTTCTTCTTATGCAAGTTGG
ATAGGCAAGAGGTTGCCTTCGGAGGCTGAATGGGAAGTGGCGGCTGCCGGAGGGAAGTTAGGAATGCGTTACCCTACCGG
AGAAGATGTAGATAAAAGCAAAGCTAACTTCTTTAGTTCAGATACAACGCCGGTTATGAGCTATCCAGCTAATATACTAG
GTCTTTATGATATGGCAGGGAATATATACGAATGGTGCCAGGATTGGTACAGTTACGATTTTTATGAAAATTCCGCTTTA
GAGCCAGATTCTCCTCAGGGGCCTCCTCAAGGTGTCTATCGCGTTTTGCGAGGAGGGTGTTGGAAGAGTCTAAAAGAGGA
TCTCCGTTGTGCACATCGCCACCGAAACAATCCAGGGGCAATTAATAGCACCTATGGGTTTCGTTGTGCGAAAGATGTAA
AATAA

Upstream 100 bases:

>100_bases
GTTGTAGACTGATCGAAAAGCTACAAGTATAGTACTAGGAAGAGAAGGCACTTAGTAGGCTCAGTCAAAGAACTTCGAAA
CAGGTATAAGGGTCCCAAAA

Downstream 100 bases:

>100_bases
AGGGCTTGCTATGAGAGCTTTGTCTCAAGACTATTATATTGCTTTATGTACAGAGTTGATAGAGCATGATCGGCGTTATT
ATGTGTTGGATCGACCTACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MEEQSTVEYWGDYKVIAELEQGLWSRDVLTEHRFIKKRYVLKILPSELSLSEDFMKVFQKVIVQLATIRHPSLVAIENVS
QEKDRYFIVTEENSGTISLAKYLSGRKLSEEEIVYLIQQLCEVLELVHEIGLAHGQINLHSVHVSFINGVANIYLPEVGF
ASLLRERMFSSIMQKASMQESVECIRDLLVFEAPEEKSTNHRATDAYSVGVLAYYLLVGAFPWGAFPKPSSCIPDSIYDW
DSFILSCLQQQQQARPKRLRDALKKKTLGEQLQSTIDHCRESLRAMEVQEEVSEPIAPTSLIREGEKLFEGKEEQQAFVL
VEAKSIDEAMVTTVDSEEVSESGEGYVNPLQSLLAREPVVSRYVEIEREEVKPQPLSTEMVFIEGGDFSRGSRDGQRDEL
PVHNITLPGFLLDIHPVTNEHFVRFLEFIGGEQDEHYNELIRLKDSRIQRRSGRLIIEPGYAKHPVVGVTWYGASSYASW
IGKRLPSEAEWEVAAAGGKLGMRYPTGEDVDKSKANFFSSDTTPVMSYPANILGLYDMAGNIYEWCQDWYSYDFYENSAL
EPDSPQGPPQGVYRVLRGGCWKSLKEDLRCAHRHRNNPGAINSTYGFRCAKDVK

Sequences:

>Translated_614_residues
MEEQSTVEYWGDYKVIAELEQGLWSRDVLTEHRFIKKRYVLKILPSELSLSEDFMKVFQKVIVQLATIRHPSLVAIENVS
QEKDRYFIVTEENSGTISLAKYLSGRKLSEEEIVYLIQQLCEVLELVHEIGLAHGQINLHSVHVSFINGVANIYLPEVGF
ASLLRERMFSSIMQKASMQESVECIRDLLVFEAPEEKSTNHRATDAYSVGVLAYYLLVGAFPWGAFPKPSSCIPDSIYDW
DSFILSCLQQQQQARPKRLRDALKKKTLGEQLQSTIDHCRESLRAMEVQEEVSEPIAPTSLIREGEKLFEGKEEQQAFVL
VEAKSIDEAMVTTVDSEEVSESGEGYVNPLQSLLAREPVVSRYVEIEREEVKPQPLSTEMVFIEGGDFSRGSRDGQRDEL
PVHNITLPGFLLDIHPVTNEHFVRFLEFIGGEQDEHYNELIRLKDSRIQRRSGRLIIEPGYAKHPVVGVTWYGASSYASW
IGKRLPSEAEWEVAAAGGKLGMRYPTGEDVDKSKANFFSSDTTPVMSYPANILGLYDMAGNIYEWCQDWYSYDFYENSAL
EPDSPQGPPQGVYRVLRGGCWKSLKEDLRCAHRHRNNPGAINSTYGFRCAKDVK
>Mature_614_residues
MEEQSTVEYWGDYKVIAELEQGLWSRDVLTEHRFIKKRYVLKILPSELSLSEDFMKVFQKVIVQLATIRHPSLVAIENVS
QEKDRYFIVTEENSGTISLAKYLSGRKLSEEEIVYLIQQLCEVLELVHEIGLAHGQINLHSVHVSFINGVANIYLPEVGF
ASLLRERMFSSIMQKASMQESVECIRDLLVFEAPEEKSTNHRATDAYSVGVLAYYLLVGAFPWGAFPKPSSCIPDSIYDW
DSFILSCLQQQQQARPKRLRDALKKKTLGEQLQSTIDHCRESLRAMEVQEEVSEPIAPTSLIREGEKLFEGKEEQQAFVL
VEAKSIDEAMVTTVDSEEVSESGEGYVNPLQSLLAREPVVSRYVEIEREEVKPQPLSTEMVFIEGGDFSRGSRDGQRDEL
PVHNITLPGFLLDIHPVTNEHFVRFLEFIGGEQDEHYNELIRLKDSRIQRRSGRLIIEPGYAKHPVVGVTWYGASSYASW
IGKRLPSEAEWEVAAAGGKLGMRYPTGEDVDKSKANFFSSDTTPVMSYPANILGLYDMAGNIYEWCQDWYSYDFYENSAL
EPDSPQGPPQGVYRVLRGGCWKSLKEDLRCAHRHRNNPGAINSTYGFRCAKDVK

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain

Homologues:

Organism=Homo sapiens, GI257470975, Length=283, Percent_Identity=32.1554770318021, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI38202250, Length=303, Percent_Identity=30.6930693069307, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI194248087, Length=277, Percent_Identity=32.8519855595668, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI194248088, Length=287, Percent_Identity=32.404181184669, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI257470977, Length=300, Percent_Identity=28, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI226437577, Length=170, Percent_Identity=35.2941176470588, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20130397, Length=289, Percent_Identity=29.4117647058824, Blast_Score=96, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PKN1_CHLMU (Q9PKP3)

Other databases:

- EMBL:   AE002160
- PIR:   H81703
- RefSeq:   NP_296799.1
- ProteinModelPortal:   Q9PKP3
- SMR:   Q9PKP3
- GeneID:   1245775
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0422
- TIGR:   TC_0422
- HOGENOM:   HBG413964
- OMA:   YYNELIR
- ProtClustDB:   CLSK871217
- BioCyc:   CMUR243161:TC_0422-MONOMER
- BRENDA:   2.7.11.1
- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532
- Gene3D:   G3DSA:3.90.1580.10

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase; SSF56436 C-type_lectin_fold; SSF56112 Kinase_like

EC number: =2.7.11.1

Molecular weight: Translated: 69783; Mature: 69783

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: BINDING 42-42

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEQSTVEYWGDYKVIAELEQGLWSRDVLTEHRFIKKRYVLKILPSELSLSEDFMKVFQK
CCCCCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHH
VIVQLATIRHPSLVAIENVSQEKDRYFIVTEENSGTISLAKYLSGRKLSEEEIVYLIQQL
HHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHH
CEVLELVHEIGLAHGQINLHSVHVSFINGVANIYLPEVGFASLLRERMFSSIMQKASMQE
HHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SVECIRDLLVFEAPEEKSTNHRATDAYSVGVLAYYLLVGAFPWGAFPKPSSCIPDSIYDW
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
DSFILSCLQQQQQARPKRLRDALKKKTLGEQLQSTIDHCRESLRAMEVQEEVSEPIAPTS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LIREGEKLFEGKEEQQAFVLVEAKSIDEAMVTTVDSEEVSESGEGYVNPLQSLLAREPVV
HHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCHHH
SRYVEIEREEVKPQPLSTEMVFIEGGDFSRGSRDGQRDELPVHNITLPGFLLDIHPVTNE
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCHH
HFVRFLEFIGGEQDEHYNELIRLKDSRIQRRSGRLIIEPGYAKHPVVGVTWYGASSYASW
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEECCCHHHHHH
IGKRLPSEAEWEVAAAGGKLGMRYPTGEDVDKSKANFFSSDTTPVMSYPANILGLYDMAG
HHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHC
NIYEWCQDWYSYDFYENSALEPDSPQGPPQGVYRVLRGGCWKSLKEDLRCAHRHRNNPGA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
INSTYGFRCAKDVK
CCCCCCCCCCCCCC
>Mature Secondary Structure
MEEQSTVEYWGDYKVIAELEQGLWSRDVLTEHRFIKKRYVLKILPSELSLSEDFMKVFQK
CCCCCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHH
VIVQLATIRHPSLVAIENVSQEKDRYFIVTEENSGTISLAKYLSGRKLSEEEIVYLIQQL
HHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHH
CEVLELVHEIGLAHGQINLHSVHVSFINGVANIYLPEVGFASLLRERMFSSIMQKASMQE
HHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SVECIRDLLVFEAPEEKSTNHRATDAYSVGVLAYYLLVGAFPWGAFPKPSSCIPDSIYDW
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
DSFILSCLQQQQQARPKRLRDALKKKTLGEQLQSTIDHCRESLRAMEVQEEVSEPIAPTS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LIREGEKLFEGKEEQQAFVLVEAKSIDEAMVTTVDSEEVSESGEGYVNPLQSLLAREPVV
HHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCHHH
SRYVEIEREEVKPQPLSTEMVFIEGGDFSRGSRDGQRDELPVHNITLPGFLLDIHPVTNE
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCHH
HFVRFLEFIGGEQDEHYNELIRLKDSRIQRRSGRLIIEPGYAKHPVVGVTWYGASSYASW
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEECCCHHHHHH
IGKRLPSEAEWEVAAAGGKLGMRYPTGEDVDKSKANFFSSDTTPVMSYPANILGLYDMAG
HHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHC
NIYEWCQDWYSYDFYENSALEPDSPQGPPQGVYRVLRGGCWKSLKEDLRCAHRHRNNPGA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
INSTYGFRCAKDVK
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935