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Identifier: 15834682

GI number: 15834682

Start: 66515

End: 67282

Strand: Direct

Name: Not Available

Synonym: TC0057

Alternate gene names: 15834682

Gene position: 66515-67282 (Clockwise)

Preceding gene: 15834681

Following gene: 15834683

Centisome position: 6.2

GC content: 42.19

Gene sequence:

>768_bases
ATGCTTCATCTATACGATTTACACGTGTGTTGTGAAGAAAAAAAGATTTTGGAAGGGTTGTCTTTGTCTATTCGCCCAGG
AGAACTCCATATCATTATGGGGCCTAATGGAGCAGGGAAATCCACGTTAGCTAAAGTTCTGTCTGGGGATGACAGTGTAG
AGGTAGCTTCAGGGAGGATGACTTTATCGGGAAGCGACTTAATTGAGATGTCTCCGGAGAAAAGGGCTCATGCAGGGATG
TTCATTAGTTTTCAACATCCTCCAGAAATTCCCGGAGTCAATAATCGTCTTTTTTTAAAAGAGGCTTGTAATGCTTGTAG
AAAAGCTCGTAATCAAGAGGTGTTGGAAGATTCTGCTTTCAATGAGTTGCTTGCGAGTTTAGAAGAAACTTATGGATTCC
CAGGATTTCATTTTTTCCCTGATAGAAATGTCAATGAAGGGTTTTCAGGGGGAGAGAAAAAAAAGAACGAACTTTGGCAA
ATGTTGATCTTGGAACCCAAAATGGTTGTGCTAGATGAACCCGACTCAGGGCTTGATGTAGATGCCCTGAAGGGCATTTG
CTCTGTTGTACAAACCTATCGACGTAAACATCCTGAAACTGCCTTTTGCATTGTGACTCATAATCCGAGACTCGGGGATC
TTCTTCACCCTGATCATGTACACATCCTTTTGAATGGGAGAGTTGTTTTTTCCGGGGATATGCATCTCATGGAGGAGCTA
GAAAGAAAGAGTTATCAAGAATTGTTGGATGTTGTTACCCGGGAGTAA

Upstream 100 bases:

>100_bases
ATGGTTTCTGTAAAGAAGTTATAGAGTTATTGCCTTTGGAATTTGCTCGAGAAGCAACAAAGTTATTAATGATTAAATTA
GAAAATAGTGTGGGCTAGAA

Downstream 100 bases:

>100_bases
GCTATGAGGGGAACTTATCAGCAAAGGCTAATTCATCCTAATGAGCGATTACTAGAAGCGCTCAGTTCTTTATGGGGCAA
ATATCAACGTGATCATGTAT

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLHLYDLHVCCEEKKILEGLSLSIRPGELHIIMGPNGAGKSTLAKVLSGDDSVEVASGRMTLSGSDLIEMSPEKRAHAGM
FISFQHPPEIPGVNNRLFLKEACNACRKARNQEVLEDSAFNELLASLEETYGFPGFHFFPDRNVNEGFSGGEKKKNELWQ
MLILEPKMVVLDEPDSGLDVDALKGICSVVQTYRRKHPETAFCIVTHNPRLGDLLHPDHVHILLNGRVVFSGDMHLMEEL
ERKSYQELLDVVTRE

Sequences:

>Translated_255_residues
MLHLYDLHVCCEEKKILEGLSLSIRPGELHIIMGPNGAGKSTLAKVLSGDDSVEVASGRMTLSGSDLIEMSPEKRAHAGM
FISFQHPPEIPGVNNRLFLKEACNACRKARNQEVLEDSAFNELLASLEETYGFPGFHFFPDRNVNEGFSGGEKKKNELWQ
MLILEPKMVVLDEPDSGLDVDALKGICSVVQTYRRKHPETAFCIVTHNPRLGDLLHPDHVHILLNGRVVFSGDMHLMEEL
ERKSYQELLDVVTRE
>Mature_255_residues
MLHLYDLHVCCEEKKILEGLSLSIRPGELHIIMGPNGAGKSTLAKVLSGDDSVEVASGRMTLSGSDLIEMSPEKRAHAGM
FISFQHPPEIPGVNNRLFLKEACNACRKARNQEVLEDSAFNELLASLEETYGFPGFHFFPDRNVNEGFSGGEKKKNELWQ
MLILEPKMVVLDEPDSGLDVDALKGICSVVQTYRRKHPETAFCIVTHNPRLGDLLHPDHVHILLNGRVVFSGDMHLMEEL
ERKSYQELLDVVTRE

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI62526033, Length=227, Percent_Identity=27.7533039647577, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787972, Length=245, Percent_Identity=48.5714285714286, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI1787370, Length=228, Percent_Identity=24.1228070175439, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081709, Length=193, Percent_Identity=24.3523316062176, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787500, Length=184, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081791, Length=179, Percent_Identity=27.3743016759777, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790190, Length=189, Percent_Identity=26.984126984127, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786253, Length=215, Percent_Identity=26.5116279069767, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790467, Length=231, Percent_Identity=24.6753246753247, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789032, Length=222, Percent_Identity=27.027027027027, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787029, Length=200, Percent_Identity=27.5, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789593, Length=201, Percent_Identity=26.865671641791, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1789891, Length=218, Percent_Identity=27.0642201834862, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=238, Percent_Identity=27.3109243697479, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=246, Percent_Identity=27.6422764227642, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=246, Percent_Identity=27.6422764227642, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=246, Percent_Identity=27.6422764227642, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324498, Length=254, Percent_Identity=25.9842519685039, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24662800, Length=222, Percent_Identity=30.1801801801802, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85816269, Length=222, Percent_Identity=27.4774774774775, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580553, Length=222, Percent_Identity=27.4774774774775, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85724864, Length=222, Percent_Identity=27.4774774774775, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580555, Length=222, Percent_Identity=27.4774774774775, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 28576; Mature: 28576

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLYDLHVCCEEKKILEGLSLSIRPGELHIIMGPNGAGKSTLAKVLSGDDSVEVASGRM
CEEEEEEHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCHHHHHHHHCCCCCEEEECCEE
TLSGSDLIEMSPEKRAHAGMFISFQHPPEIPGVNNRLFLKEACNACRKARNQEVLEDSAF
EECCCCCEECCCCCHHHCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHCCHHHHHHHHH
NELLASLEETYGFPGFHFFPDRNVNEGFSGGEKKKNELWQMLILEPKMVVLDEPDSGLDV
HHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCCH
DALKGICSVVQTYRRKHPETAFCIVTHNPRLGDLLHPDHVHILLNGRVVFSGDMHLMEEL
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECEEEEECCHHHHHHH
ERKSYQELLDVVTRE
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MLHLYDLHVCCEEKKILEGLSLSIRPGELHIIMGPNGAGKSTLAKVLSGDDSVEVASGRM
CEEEEEEHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCHHHHHHHHCCCCCEEEECCEE
TLSGSDLIEMSPEKRAHAGMFISFQHPPEIPGVNNRLFLKEACNACRKARNQEVLEDSAF
EECCCCCEECCCCCHHHCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHCCHHHHHHHHH
NELLASLEETYGFPGFHFFPDRNVNEGFSGGEKKKNELWQMLILEPKMVVLDEPDSGLDV
HHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCCH
DALKGICSVVQTYRRKHPETAFCIVTHNPRLGDLLHPDHVHILLNGRVVFSGDMHLMEEL
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECEEEEECCHHHHHHH
ERKSYQELLDVVTRE
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]