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The map label for this gene is cat2

Identifier: 16120156

GI number: 16120156

Start: 180135

End: 181598

Strand: Reverse

Name: cat2

Synonym: VNG6220G

Alternate gene names: 16120156

Gene position: 181598-180135 (Counterclockwise)

Preceding gene: 16120157

Following gene: 16120155

Centisome position: 49.7

GC content: 65.78

Gene sequence:

>1464_bases
ATGAGCAGCAGCCAAACGCGATCCCCCGACGCCGAACTCGGATTGCTCGACGCCACGATGATCGGCATGGGGGCGATGAT
CGGTGCCGGGATCTTCGTTTTGACCGGCCTCGCGGCCGAAATCGCTGGGCCGGCCGCTATCCTCGTGTTCGCGCTGAACG
GCGTCGTCACCGCGTTCACCGGACTCTCGTACGCCGAACTCGCGGCCTCGATCCCGAAAAGCGGCGGCGGCTACGCGTTC
GTGCGCGAGATCTTCGGCGATTTCTCCTCGTTCATCATGGGGTGGATGCTGTGGTTCGCGTACATGATCGCGGGCGCGCT
GTACGCACTCGGGTTCGCGCCCAACTTCCTCGAACTGCTGCACGTCTACGGCCTGGTGGCCCCACCGGACCAGGTCGGCG
CGATCGCCGTCCCGCTGCTCGACGCCTCAGTGCCCGCCGCGTTCGTGCTGGCGTTCATCGCAGTGCTCGGACTGGTGGCG
CTTAACGCCGTGTCCACAGCGGCAAGCGGGAGCGCTGAAACCATCTTCACGATCATCAAAGTGAGCATCCTGGTGGTGTT
CGTGGCGTTCGGCGCGACGTCCCCGCTGTTCTCCGGGGCCGAATTCCAGCCGCTGTTCGGAGTGGGTGGCGGCCCGGCGG
CGATCCTGCCCGCCATGGGACTGACGTTCATCGCCTTCGAGGGCTACGACCTCATCACCACCGTCACGGAGGAAGTCAAA
AACCCCCGCGAGAACATCCCGAAGGCGATCTTCGTGAGCCTGATCGCGACCGTGATCGTCTACCTGGCAGTCGTCACCGT
CGCCGTCGGCACGCTCGGCGCTGACGGCCTGGCGGCGGCCGGCGAAGCGGGCATCGCGGAGGCAGCCACGTCGTTCATGC
CCACCGGACTGCCGATCATCCAGAACGGCGGCGCACTCATCGTCTTCGGCGCGGTGTTCTCGACGCTCACGGCGCTGAAC
GCGGTCGTGATCGCGTCCTCACGGGTCGCATTCTCGATGGGCCGTGAGGGGCAACTGCTCCCGTCGTTCGGCCAGATCCA
CCACCGCTACGGGACGCCGTTCGTCGCGATCATCGCCAGCGCGGTGGTGATGTTGGCGTCGGTCGCGTTGCCCACGCAGA
GCGCCGGCAACATGTCCAGTCTGTTCTTCCTGCTGTCGTTCATCATCGTCAACGTCGCCGTCATCAGACTGCGCCGCGAG
CGCCCCGACATGAACCGGCCTTACGAGATGCCGTTCTATCCTGCGCCGCCACTCATCGGCATCGCGCTCAATCTCGTGTT
GTCCGTCGTGCTGGTCGACTACCTCGTGCGCACGGATCCGCTTGCGTTGGCGCTCAGCGCGGCCTGGATCGTTCTGGGGA
CGGCTGCCTACTACGCACACGCCAGCCGGCAGTCGGCCGCCGGCGACGACGAGGACACCACGACTATTTCGGCGGACGCC
GAACACACGCCACATGACCACTAA

Upstream 100 bases:

>100_bases
GTCGCCACACCTATCACCGCTCGTATGCAAGAAATCAAGTGTGTCGGCTGAGTTGTCCCGTTCACACGATGGATACACTA
CACCTCCACAGTAGTATCTG

Downstream 100 bases:

>100_bases
CCGAGACCTCATCATCGCGGGCGGCGGGCGCGTCGGCTTCCAGACGGCTGAACTCCTCGCCGACCGCGGCCACGACGTGA
CGATCATCGAGCGCGACACC

Product: cationic amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSSSQTRSPDAELGLLDATMIGMGAMIGAGIFVLTGLAAEIAGPAAILVFALNGVVTAFTGLSYAELAASIPKSGGGYAF
VREIFGDFSSFIMGWMLWFAYMIAGALYALGFAPNFLELLHVYGLVAPPDQVGAIAVPLLDASVPAAFVLAFIAVLGLVA
LNAVSTAASGSAETIFTIIKVSILVVFVAFGATSPLFSGAEFQPLFGVGGGPAAILPAMGLTFIAFEGYDLITTVTEEVK
NPRENIPKAIFVSLIATVIVYLAVVTVAVGTLGADGLAAAGEAGIAEAATSFMPTGLPIIQNGGALIVFGAVFSTLTALN
AVVIASSRVAFSMGREGQLLPSFGQIHHRYGTPFVAIIASAVVMLASVALPTQSAGNMSSLFFLLSFIIVNVAVIRLRRE
RPDMNRPYEMPFYPAPPLIGIALNLVLSVVLVDYLVRTDPLALALSAAWIVLGTAAYYAHASRQSAAGDDEDTTTISADA
EHTPHDH

Sequences:

>Translated_487_residues
MSSSQTRSPDAELGLLDATMIGMGAMIGAGIFVLTGLAAEIAGPAAILVFALNGVVTAFTGLSYAELAASIPKSGGGYAF
VREIFGDFSSFIMGWMLWFAYMIAGALYALGFAPNFLELLHVYGLVAPPDQVGAIAVPLLDASVPAAFVLAFIAVLGLVA
LNAVSTAASGSAETIFTIIKVSILVVFVAFGATSPLFSGAEFQPLFGVGGGPAAILPAMGLTFIAFEGYDLITTVTEEVK
NPRENIPKAIFVSLIATVIVYLAVVTVAVGTLGADGLAAAGEAGIAEAATSFMPTGLPIIQNGGALIVFGAVFSTLTALN
AVVIASSRVAFSMGREGQLLPSFGQIHHRYGTPFVAIIASAVVMLASVALPTQSAGNMSSLFFLLSFIIVNVAVIRLRRE
RPDMNRPYEMPFYPAPPLIGIALNLVLSVVLVDYLVRTDPLALALSAAWIVLGTAAYYAHASRQSAAGDDEDTTTISADA
EHTPHDH
>Mature_486_residues
SSSQTRSPDAELGLLDATMIGMGAMIGAGIFVLTGLAAEIAGPAAILVFALNGVVTAFTGLSYAELAASIPKSGGGYAFV
REIFGDFSSFIMGWMLWFAYMIAGALYALGFAPNFLELLHVYGLVAPPDQVGAIAVPLLDASVPAAFVLAFIAVLGLVAL
NAVSTAASGSAETIFTIIKVSILVVFVAFGATSPLFSGAEFQPLFGVGGGPAAILPAMGLTFIAFEGYDLITTVTEEVKN
PRENIPKAIFVSLIATVIVYLAVVTVAVGTLGADGLAAAGEAGIAEAATSFMPTGLPIIQNGGALIVFGAVFSTLTALNA
VVIASSRVAFSMGREGQLLPSFGQIHHRYGTPFVAIIASAVVMLASVALPTQSAGNMSSLFFLLSFIIVNVAVIRLRRER
PDMNRPYEMPFYPAPPLIGIALNLVLSVVLVDYLVRTDPLALALSAAWIVLGTAAYYAHASRQSAAGDDEDTTTISADAE
HTPHDH

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=448, Percent_Identity=27.6785714285714, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI7657683, Length=458, Percent_Identity=25.764192139738, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI115648063, Length=423, Percent_Identity=27.4231678486998, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI115648022, Length=423, Percent_Identity=27.4231678486998, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI33286428, Length=465, Percent_Identity=26.8817204301075, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI110347453, Length=367, Percent_Identity=29.4277929155313, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI186910308, Length=421, Percent_Identity=26.603325415677, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI186910306, Length=421, Percent_Identity=26.603325415677, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI186910304, Length=421, Percent_Identity=26.603325415677, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI258614003, Length=438, Percent_Identity=26.4840182648402, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI258614005, Length=438, Percent_Identity=26.4840182648402, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI114326544, Length=421, Percent_Identity=26.8408551068884, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI114326550, Length=421, Percent_Identity=26.8408551068884, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI9790235, Length=334, Percent_Identity=28.4431137724551, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI181337167, Length=400, Percent_Identity=25.75, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI187423910, Length=431, Percent_Identity=25.2900232018561, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI7657591, Length=431, Percent_Identity=25.2900232018561, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI258645169, Length=437, Percent_Identity=25.4004576659039, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI71999149, Length=425, Percent_Identity=24.2352941176471, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI33286430, Length=254, Percent_Identity=25.5905511811024, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786694, Length=406, Percent_Identity=28.5714285714286, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87081869, Length=487, Percent_Identity=24.8459958932238, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788480, Length=467, Percent_Identity=27.4089935760171, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081915, Length=416, Percent_Identity=27.1634615384615, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082250, Length=469, Percent_Identity=25.1599147121535, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789017, Length=458, Percent_Identity=23.1441048034935, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786789, Length=478, Percent_Identity=24.6861924686192, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790653, Length=470, Percent_Identity=22.7659574468085, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786302, Length=437, Percent_Identity=23.3409610983982, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081708, Length=508, Percent_Identity=23.0314960629921, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540018, Length=438, Percent_Identity=26.027397260274, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17532491, Length=404, Percent_Identity=26.980198019802, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17531343, Length=365, Percent_Identity=26.8493150684932, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17533459, Length=408, Percent_Identity=28.921568627451, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI32566699, Length=383, Percent_Identity=27.4151436031332, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17568033, Length=425, Percent_Identity=23.7647058823529, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71993915, Length=407, Percent_Identity=24.5700245700246, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320364, Length=503, Percent_Identity=23.4592445328032, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24668806, Length=406, Percent_Identity=30.5418719211823, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21356285, Length=406, Percent_Identity=30.5418719211823, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24668802, Length=406, Percent_Identity=30.5418719211823, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24667468, Length=411, Percent_Identity=30.9002433090024, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI221512776, Length=408, Percent_Identity=28.6764705882353, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24666159, Length=408, Percent_Identity=28.6764705882353, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI221331183, Length=465, Percent_Identity=26.2365591397849, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17647653, Length=465, Percent_Identity=26.2365591397849, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24664379, Length=465, Percent_Identity=26.2365591397849, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21357367, Length=441, Percent_Identity=25.6235827664399, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24651635, Length=419, Percent_Identity=25.2983293556086, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24651633, Length=419, Percent_Identity=25.2983293556086, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI116007818, Length=409, Percent_Identity=28.361858190709, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI85725152, Length=409, Percent_Identity=28.361858190709, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281366235, Length=409, Percent_Identity=28.361858190709, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI116007820, Length=409, Percent_Identity=28.361858190709, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24641993, Length=429, Percent_Identity=25.6410256410256, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24641995, Length=429, Percent_Identity=25.6410256410256, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI161077963, Length=416, Percent_Identity=26.2019230769231, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45550968, Length=479, Percent_Identity=26.0960334029228, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19921172, Length=479, Percent_Identity=26.0960334029228, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50385; Mature: 50254

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSQTRSPDAELGLLDATMIGMGAMIGAGIFVLTGLAAEIAGPAAILVFALNGVVTAFT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GLSYAELAASIPKSGGGYAFVREIFGDFSSFIMGWMLWFAYMIAGALYALGFAPNFLELL
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HVYGLVAPPDQVGAIAVPLLDASVPAAFVLAFIAVLGLVALNAVSTAASGSAETIFTIIK
HHHCCCCCCCCCCEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VSILVVFVAFGATSPLFSGAEFQPLFGVGGGPAAILPAMGLTFIAFEGYDLITTVTEEVK
HHHHHHHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHHCCHHEEEECCCHHHHHHHHHHC
NPRENIPKAIFVSLIATVIVYLAVVTVAVGTLGADGLAAAGEAGIAEAATSFMPTGLPII
CCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEE
QNGGALIVFGAVFSTLTALNAVVIASSRVAFSMGREGQLLPSFGQIHHRYGTPFVAIIAS
ECCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHH
AVVMLASVALPTQSAGNMSSLFFLLSFIIVNVAVIRLRRERPDMNRPYEMPFYPAPPLIG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
IALNLVLSVVLVDYLVRTDPLALALSAAWIVLGTAAYYAHASRQSAAGDDEDTTTISADA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
EHTPHDH
CCCCCCC
>Mature Secondary Structure 
SSSQTRSPDAELGLLDATMIGMGAMIGAGIFVLTGLAAEIAGPAAILVFALNGVVTAFT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GLSYAELAASIPKSGGGYAFVREIFGDFSSFIMGWMLWFAYMIAGALYALGFAPNFLELL
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HVYGLVAPPDQVGAIAVPLLDASVPAAFVLAFIAVLGLVALNAVSTAASGSAETIFTIIK
HHHCCCCCCCCCCEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VSILVVFVAFGATSPLFSGAEFQPLFGVGGGPAAILPAMGLTFIAFEGYDLITTVTEEVK
HHHHHHHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHHCCHHEEEECCCHHHHHHHHHHC
NPRENIPKAIFVSLIATVIVYLAVVTVAVGTLGADGLAAAGEAGIAEAATSFMPTGLPII
CCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEE
QNGGALIVFGAVFSTLTALNAVVIASSRVAFSMGREGQLLPSFGQIHHRYGTPFVAIIAS
ECCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHH
AVVMLASVALPTQSAGNMSSLFFLLSFIIVNVAVIRLRRERPDMNRPYEMPFYPAPPLIG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
IALNLVLSVVLVDYLVRTDPLALALSAAWIVLGTAAYYAHASRQSAAGDDEDTTTISADA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
EHTPHDH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]