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The map label for this gene is trkA2

Identifier: 16120119

GI number: 16120119

Start: 146432

End: 147136

Strand: Reverse

Name: trkA2

Synonym: VNG6175G

Alternate gene names: 16120119

Gene position: 147136-146432 (Counterclockwise)

Preceding gene: 16120125

Following gene: 16120116

Centisome position: 40.26

GC content: 53.76

Gene sequence:

>705_bases
ATGACGACAGTAATCGTTGGTGCCGGCAGAATAGGTTCGAGTGTAATCGAACTAGCGGCCGATGCCAACATCGGCGTCAC
TGTAATCGAACAGGAGCACGAGCGAGCTCACGAGTTTAAAGCGGACGAGAACTGCCACGTCATCCACGATGACGCCACCG
AACGCGAAACGCTGCACGAGGCTGAGGTGGGCAACGCTGATGCAATCATCGCAACTACTGATCAAGACACCACGAACCTG
ATGGTGCTGATGTTAGCCCGTGAGTTGGGCTGTGAAACACTCGTCAGTGTTGTCCACGCGGAGGAAAACATTCCACTGTT
TCGACAGCTAGGAGCCACTATCATCGAGAACCCACAACGATTGATCGCGGAATATCTGTTTCGAGGCACCCATGATCCGG
GCATTCAGGGCTTCATGCACGTTGGCGATAGAGACGGTGGAGCTGAAGTCTTTGAGATCTCAGTTGCAGATGGGGCGCCA
ATCATCGGAAAGACGCTTGAACAGGCAGACGTCGCGGGGTTCCTTCCGCCCAGCATGGTTGTCGTTGCAGTCGAACGTGA
CGGTGAAATCATCATCCCCCGAGGTAACACACAGATAGAGACGGACGACCTCGTTACCGTGTTCTCCAAGGAGGGGATCA
TTAACGAGGTGGTTGAACCGTTCAAACCTGAAGCAAAACGGACCGGTGATTCTGATACGGAGTAG

Upstream 100 bases:

>100_bases
GAGCCTCGATGTTTTCTTTCGCTCCCGATGAAGATGCTCGCTGCCACAGTTCTGGATCTACCAGTGTTTTATATTTCCCC
TCCGCAAAGTCGATATCACT

Downstream 100 bases:

>100_bases
CATCCAGAGTGTTTTACAGCAATTCTGTTGTAAATCGAGTTGGGTCGTCGAATCCCTCACTCCTCCGAGGCGAAACTCGC
GGGGACAACAGAAGTTTCGT

Product: TRK potassium uptake system protein

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTTVIVGAGRIGSSVIELAADANIGVTVIEQEHERAHEFKADENCHVIHDDATERETLHEAEVGNADAIIATTDQDTTNL
MVLMLARELGCETLVSVVHAEENIPLFRQLGATIIENPQRLIAEYLFRGTHDPGIQGFMHVGDRDGGAEVFEISVADGAP
IIGKTLEQADVAGFLPPSMVVVAVERDGEIIIPRGNTQIETDDLVTVFSKEGIINEVVEPFKPEAKRTGDSDTE

Sequences:

>Translated_234_residues
MTTVIVGAGRIGSSVIELAADANIGVTVIEQEHERAHEFKADENCHVIHDDATERETLHEAEVGNADAIIATTDQDTTNL
MVLMLARELGCETLVSVVHAEENIPLFRQLGATIIENPQRLIAEYLFRGTHDPGIQGFMHVGDRDGGAEVFEISVADGAP
IIGKTLEQADVAGFLPPSMVVVAVERDGEIIIPRGNTQIETDDLVTVFSKEGIINEVVEPFKPEAKRTGDSDTE
>Mature_233_residues
TTVIVGAGRIGSSVIELAADANIGVTVIEQEHERAHEFKADENCHVIHDDATERETLHEAEVGNADAIIATTDQDTTNLM
VLMLARELGCETLVSVVHAEENIPLFRQLGATIIENPQRLIAEYLFRGTHDPGIQGFMHVGDRDGGAEVFEISVADGAPI
IGKTLEQADVAGFLPPSMVVVAVERDGEIIIPRGNTQIETDDLVTVFSKEGIINEVVEPFKPEAKRTGDSDTE

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=226, Percent_Identity=27.4336283185841, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 25292; Mature: 25160

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVIVGAGRIGSSVIELAADANIGVTVIEQEHERAHEFKADENCHVIHDDATERETLHE
CCEEEEECCCHHHHHHHHHCCCCCCEEEEECHHHHHHHCCCCCCCEEEECCCHHHHHHHH
AEVGNADAIIATTDQDTTNLMVLMLARELGCETLVSVVHAEENIPLFRQLGATIIENPQR
HCCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHCHHHHCCHHH
LIAEYLFRGTHDPGIQGFMHVGDRDGGAEVFEISVADGAPIIGKTLEQADVAGFLPPSMV
HHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEE
VVAVERDGEIIIPRGNTQIETDDLVTVFSKEGIINEVVEPFKPEAKRTGDSDTE
EEEEECCCCEEEECCCCEECCCCEEEEHHCCCHHHHHHHCCCCCHHCCCCCCCC
>Mature Secondary Structure 
TTVIVGAGRIGSSVIELAADANIGVTVIEQEHERAHEFKADENCHVIHDDATERETLHE
CEEEEECCCHHHHHHHHHCCCCCCEEEEECHHHHHHHCCCCCCCEEEECCCHHHHHHHH
AEVGNADAIIATTDQDTTNLMVLMLARELGCETLVSVVHAEENIPLFRQLGATIIENPQR
HCCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHCHHHHCCHHH
LIAEYLFRGTHDPGIQGFMHVGDRDGGAEVFEISVADGAPIIGKTLEQADVAGFLPPSMV
HHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEE
VVAVERDGEIIIPRGNTQIETDDLVTVFSKEGIINEVVEPFKPEAKRTGDSDTE
EEEEECCCCEEEECCCCEECCCCEEEEHHCCCHHHHHHHCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]