Click here to switch to the map view.

The map label for this gene is orc2

Identifier: 16120112

GI number: 16120112

Start: 139850

End: 140644

Strand: Reverse

Name: orc2

Synonym: VNG6164G

Alternate gene names: 16120112

Gene position: 140644-139850 (Counterclockwise)

Preceding gene: 16120113

Following gene: 16120110

Centisome position: 38.49

GC content: 54.97

Gene sequence:

>795_bases
ATGACGCCCGACTCTTCACCCAGTTCTGTCGACGATCCACTCTTTGAATCCGGGCATCGTATCTTCGCGAACAAGGATCT
CCTGAAAATCGGCCACGTGCCGGAGGCTGACCGGATCGTCGGTCGTGACGAGGAAATCTCGAAGCTCGCGAAACGTCTCA
ACGGTGCTGTCCACGGGTACTCCCCGGAGAACGTGATGATCTACGGGAAAACTGGGACCGGTAAATCTCTCGTTTCAAAA
CACGTCTGCCAGCGAGCTCAAAATGCCGCTCAAGATGGCGTCGAGATTGGAACAGCGTATATCGACTGTGCTGAAGACAA
TACCGAGACCCAAGCAATCTCCTCACTTGCCGCGAAGCTGAACAATGAATCTTCGACCGGAATCTCCGTCCCTCATACCG
GCCTCAGTACGTCGAAATACTACAAACTCCTCTGGAAGACGCTCGACGCTCAATTCGATTCTGTGATCATCATCCTCGAC
GAGATCGACTTGATGAACGACGACAGCGTGCTGATGAAGCTCTCGCGCGCTGAGGAGGCGGGGAAAATCGACTGTAGCGT
CGGCGTCATCGCGATCAGCAACAAGATACAGTACGTCGACAACGTGAACGAGCGCGTGAAAAGCAGCTTCCAGCACAAGG
AGCTGTTCTTCAAGCCATACGACGCCAACCAGCTCCGGGAGATCATGTTCAACCGCGAGGATTTCTCGTCGTCGACGACC
ACGTACTCGATATCCTGGCCCGGGTGGACTGCCAGTTCCTGCTCACGCGCTCGCTTCAAAGCGGCCACGTTCTGA

Upstream 100 bases:

>100_bases
GGCATTTTCCCGCTGATATCGGACAAGAAACGTCGGAAACGTGGGATGGCGTTCTCCACTAGATTTATACCCCCTCCCCG
CTCACACCGTGTGATATTCA

Downstream 100 bases:

>100_bases
GTATTCTGAGAGTACCCCTCTAGCGGCTTGGAGACACAATTCCGTTCGACGAGCCGCTCACTGCTACGTTGCCCGCCTGC
AGTTCGTTGACTGCTCGTTC

Product: orc / cell division control protein 6

Products: NA

Alternate protein names: CDC6 homolog 6 [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTPDSSPSSVDDPLFESGHRIFANKDLLKIGHVPEADRIVGRDEEISKLAKRLNGAVHGYSPENVMIYGKTGTGKSLVSK
HVCQRAQNAAQDGVEIGTAYIDCAEDNTETQAISSLAAKLNNESSTGISVPHTGLSTSKYYKLLWKTLDAQFDSVIIILD
EIDLMNDDSVLMKLSRAEEAGKIDCSVGVIAISNKIQYVDNVNERVKSSFQHKELFFKPYDANQLREIMFNREDFSSSTT
TYSISWPGWTASSCSRARFKAATF

Sequences:

>Translated_264_residues
MTPDSSPSSVDDPLFESGHRIFANKDLLKIGHVPEADRIVGRDEEISKLAKRLNGAVHGYSPENVMIYGKTGTGKSLVSK
HVCQRAQNAAQDGVEIGTAYIDCAEDNTETQAISSLAAKLNNESSTGISVPHTGLSTSKYYKLLWKTLDAQFDSVIIILD
EIDLMNDDSVLMKLSRAEEAGKIDCSVGVIAISNKIQYVDNVNERVKSSFQHKELFFKPYDANQLREIMFNREDFSSSTT
TYSISWPGWTASSCSRARFKAATF
>Mature_263_residues
TPDSSPSSVDDPLFESGHRIFANKDLLKIGHVPEADRIVGRDEEISKLAKRLNGAVHGYSPENVMIYGKTGTGKSLVSKH
VCQRAQNAAQDGVEIGTAYIDCAEDNTETQAISSLAAKLNNESSTGISVPHTGLSTSKYYKLLWKTLDAQFDSVIIILDE
IDLMNDDSVLMKLSRAEEAGKIDCSVGVIAISNKIQYVDNVNERVKSSFQHKELFFKPYDANQLREIMFNREDFSSSTTT
YSISWPGWTASSCSRARFKAATF

Specific function: Might be involved in the initiation of DNA replication [H]

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C [H]

EC number: NA

Molecular weight: Translated: 29146; Mature: 29015

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPDSSPSSVDDPLFESGHRIFANKDLLKIGHVPEADRIVGRDEEISKLAKRLNGAVHGY
CCCCCCCCCCCCHHHHCCCEEEECCCEEEECCCCCHHHHCCCCHHHHHHHHHHCCCCCCC
SPENVMIYGKTGTGKSLVSKHVCQRAQNAAQDGVEIGTAYIDCAEDNTETQAISSLAAKL
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEECEEEEEECCCCHHHHHHHHHHHHH
NNESSTGISVPHTGLSTSKYYKLLWKTLDAQFDSVIIILDEIDLMNDDSVLMKLSRAEEA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCC
GKIDCSVGVIAISNKIQYVDNVNERVKSSFQHKELFFKPYDANQLREIMFNREDFSSSTT
CCEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCE
TYSISWPGWTASSCSRARFKAATF
EEEEECCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
TPDSSPSSVDDPLFESGHRIFANKDLLKIGHVPEADRIVGRDEEISKLAKRLNGAVHGY
CCCCCCCCCCCHHHHCCCEEEECCCEEEECCCCCHHHHCCCCHHHHHHHHHHCCCCCCC
SPENVMIYGKTGTGKSLVSKHVCQRAQNAAQDGVEIGTAYIDCAEDNTETQAISSLAAKL
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEECEEEEEECCCCHHHHHHHHHHHHH
NNESSTGISVPHTGLSTSKYYKLLWKTLDAQFDSVIIILDEIDLMNDDSVLMKLSRAEEA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCC
GKIDCSVGVIAISNKIQYVDNVNERVKSSFQHKELFFKPYDANQLREIMFNREDFSSSTT
CCEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCE
TYSISWPGWTASSCSRARFKAATF
EEEEECCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11016950 [H]