Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 16120088

GI number: 16120088

Start: 107069

End: 109054

Strand: Direct

Name: Not Available

Synonym: VNG6136H

Alternate gene names: 16120088

Gene position: 107069-109054 (Clockwise)

Preceding gene: 16120087

Following gene: 16120089

Centisome position: 29.3

GC content: 46.12

Gene sequence:

>1986_bases
ATGGCTAAGTCACTGACGAGCGACAGTCAGTGGGAGGATATACAGTCGAAAGATTGGTTCATTGAGGCGCAAGAACTTGC
CGAAGAGAAATCCTTCTTCAACTGGCGCTTAGAGTACCCAGACATTTTCTACGACGAAGCTGGGGAAGAGAAAGAGAACC
CTGGATTTGACGTTGTTCTCGGAAATCCGCCTTATATCAACGCCATCGAGCTGAACGATATTACTACGCATGAGAAGGAC
TTGTGGAAAAAACGATTCAATTCGGCTAAGGACGCTTATGACATCTATGTCCTGTTCTTAGAACAAAGTCTTGAATTATC
CCGAACGGACGGCGTTGTTGGACTGATTGTTCCAAACAAACATTTGTCTGCTCCTTACGCGAAGACGTACCGAGAGTACA
TCATCGACAACCACCAGATGTGGAAAATATGTGACGTATCCCAGCTTGGTGTATTCGAAGACCCCAGTGTATACCCCGTC
ATTCCCTTTTTCAGAACAGAAAGAGACTTCGAAGGTGTTGACAATATTGAGATTGATAAGCCTGTTTCGACGGTTTCAAT
CTCAACCGGTAGTGAACAGATGGATGTCTGCGCTCCTAGTAAACTGACCAAAATCGGTAACAACCTCTGGGGGCCTCTAT
TGCTTGATCTAGAAGAACAGGATGCTTTCTGGAGCACAGTTGAGGACACTGTCCAGTTAGACAGCGAAGGAACTGTGCAA
GCGTCTAGTACGGCAAGTGAAGCAGAGGAATTCACGGTTGCCCTAAGTGAAGAACCTCCTAGTAAGACGAATAAGAAGTT
CATCAAAACAGGAGGAATCGACCCCTTCCAATCATTCTGGAATTCAGAAGAAGTCAGGCACCAGGGAGACTACTACACAA
AGCCTGTACTAGATATTGACCATCCCATTATCACCGACCTCCGAAGGTCACAATACAATAGTGAAAAATTGGTATTTGCG
AAAGTTGCGTCGATCTTGGAGGCGTTCGTTGATACAGATGGGGAATATGCATCTGTAGATACAAATCTGTTCTACGACTC
AAATCTTGACATCAGATACTACGGAGCCATTCTCAATAGTAACGTAGTTCTATTCCTATATTCAGGAATGTTTGGTGCTC
TGAGGATGAGAGGAGGAGATTTCCAGTTCCAAGCCCCACAGTTGAAGCAAGTCCCTGTACCTTCCATCTCAATTGATACA
CCTGACCCAGAACGTGGTAGTCGGGTTTCAACAGCGTTGGATAGCTACAAAGCTTATCTAGAGGGGAGCGCATCGAGACC
TAAGCCCGAGAAGGACGATGTAGCGCATGATTTCCTCGCTGAACTCACAGATCGGATAAGCGAGCTTAAACAAGAACGGG
AGAGTCTGAATCTCGCCTTGCTGGATTACTTGGGCATCCCGACTGCTGGTATCCCTGAGGATCTCGAAGGAAAATCTCTT
CAGGAATTACACATGCCTGCACCTGGGGTCGCTGATACGCTGCTCTCGGAGACAGGTGAAGACCTCGATGGGCTTCGCAT
TGAGGGTGTTTCGTTCAGTGGTGACAACTCGAAGCTCGTGATGTCTGTAGATGTTAGCTATAAGCCTGATGATGAGGACG
CCCGAGAAACAGACCGGTACGGTCGATTAGCCGAGAATGAATTTGAAACATATGATGCGATGGTATTCACGGGCCTTTCA
GATAAAAAGAGGACCCTGATCGAGATTTTCGTCCCAGAGGCAGTTAGTCGAGCAGGTGGATTTGCAGATTTCCGCCAAAG
TGCGACAAAGACGATTTCCCCGTTGGAGAGACTTGAAAATCTAGTACTCCCGGATCTTGATGCTATCAAAAACGGCTTAG
AGAAATACGAAGACGTCAGACAAGATGCTAACGAACTCGATGAGAAAATCAACAAGACAGATACACTAATCAACGAGATT
GTCTATAGCCTGTACGATCTCTCCACTGAAGAGATTGATATTATTGAAACCTCACTAGAGGAATGA

Upstream 100 bases:

>100_bases
GTTCGAGGCGAATGTTCTTCGTCAGCGTCTCGAAGCAATTGTTGATGTTTACACCGCCGAGGAGTTTGAGGTTAATGTTC
CGAACGGTGCCTACGAGCAG

Downstream 100 bases:

>100_bases
CTGACTTTGAGGTCGGCGATCACGTCAAGTTCGCCGGTGGGCGGGGCGAAATCACGAAGATCGAGGACCGCCCAAACGGA
GGCCAACTCCTCCATATCTA

Product: hypothetical protein

Products: NA

Alternate protein names: Endonuclease Eco57I; Adenine-specific methyltransferase activity Eco57IA; M.Eco57IA [H]

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MAKSLTSDSQWEDIQSKDWFIEAQELAEEKSFFNWRLEYPDIFYDEAGEEKENPGFDVVLGNPPYINAIELNDITTHEKD
LWKKRFNSAKDAYDIYVLFLEQSLELSRTDGVVGLIVPNKHLSAPYAKTYREYIIDNHQMWKICDVSQLGVFEDPSVYPV
IPFFRTERDFEGVDNIEIDKPVSTVSISTGSEQMDVCAPSKLTKIGNNLWGPLLLDLEEQDAFWSTVEDTVQLDSEGTVQ
ASSTASEAEEFTVALSEEPPSKTNKKFIKTGGIDPFQSFWNSEEVRHQGDYYTKPVLDIDHPIITDLRRSQYNSEKLVFA
KVASILEAFVDTDGEYASVDTNLFYDSNLDIRYYGAILNSNVVLFLYSGMFGALRMRGGDFQFQAPQLKQVPVPSISIDT
PDPERGSRVSTALDSYKAYLEGSASRPKPEKDDVAHDFLAELTDRISELKQERESLNLALLDYLGIPTAGIPEDLEGKSL
QELHMPAPGVADTLLSETGEDLDGLRIEGVSFSGDNSKLVMSVDVSYKPDDEDARETDRYGRLAENEFETYDAMVFTGLS
DKKRTLIEIFVPEAVSRAGGFADFRQSATKTISPLERLENLVLPDLDAIKNGLEKYEDVRQDANELDEKINKTDTLINEI
VYSLYDLSTEEIDIIETSLEE

Sequences:

>Translated_661_residues
MAKSLTSDSQWEDIQSKDWFIEAQELAEEKSFFNWRLEYPDIFYDEAGEEKENPGFDVVLGNPPYINAIELNDITTHEKD
LWKKRFNSAKDAYDIYVLFLEQSLELSRTDGVVGLIVPNKHLSAPYAKTYREYIIDNHQMWKICDVSQLGVFEDPSVYPV
IPFFRTERDFEGVDNIEIDKPVSTVSISTGSEQMDVCAPSKLTKIGNNLWGPLLLDLEEQDAFWSTVEDTVQLDSEGTVQ
ASSTASEAEEFTVALSEEPPSKTNKKFIKTGGIDPFQSFWNSEEVRHQGDYYTKPVLDIDHPIITDLRRSQYNSEKLVFA
KVASILEAFVDTDGEYASVDTNLFYDSNLDIRYYGAILNSNVVLFLYSGMFGALRMRGGDFQFQAPQLKQVPVPSISIDT
PDPERGSRVSTALDSYKAYLEGSASRPKPEKDDVAHDFLAELTDRISELKQERESLNLALLDYLGIPTAGIPEDLEGKSL
QELHMPAPGVADTLLSETGEDLDGLRIEGVSFSGDNSKLVMSVDVSYKPDDEDARETDRYGRLAENEFETYDAMVFTGLS
DKKRTLIEIFVPEAVSRAGGFADFRQSATKTISPLERLENLVLPDLDAIKNGLEKYEDVRQDANELDEKINKTDTLINEI
VYSLYDLSTEEIDIIETSLEE
>Mature_660_residues
AKSLTSDSQWEDIQSKDWFIEAQELAEEKSFFNWRLEYPDIFYDEAGEEKENPGFDVVLGNPPYINAIELNDITTHEKDL
WKKRFNSAKDAYDIYVLFLEQSLELSRTDGVVGLIVPNKHLSAPYAKTYREYIIDNHQMWKICDVSQLGVFEDPSVYPVI
PFFRTERDFEGVDNIEIDKPVSTVSISTGSEQMDVCAPSKLTKIGNNLWGPLLLDLEEQDAFWSTVEDTVQLDSEGTVQA
SSTASEAEEFTVALSEEPPSKTNKKFIKTGGIDPFQSFWNSEEVRHQGDYYTKPVLDIDHPIITDLRRSQYNSEKLVFAK
VASILEAFVDTDGEYASVDTNLFYDSNLDIRYYGAILNSNVVLFLYSGMFGALRMRGGDFQFQAPQLKQVPVPSISIDTP
DPERGSRVSTALDSYKAYLEGSASRPKPEKDDVAHDFLAELTDRISELKQERESLNLALLDYLGIPTAGIPEDLEGKSLQ
ELHMPAPGVADTLLSETGEDLDGLRIEGVSFSGDNSKLVMSVDVSYKPDDEDARETDRYGRLAENEFETYDAMVFTGLSD
KKRTLIEIFVPEAVSRAGGFADFRQSATKTISPLERLENLVLPDLDAIKNGLEKYEDVRQDANELDEKINKTDTLINEIV
YSLYDLSTEEIDIIETSLEE

Specific function: Recognizes the double-stranded sequences CTGAAG and CTTCAG and cleaves respectively 22 bases after C-1 and 14 bases before C'-1. Also acts as a methylase that causes specific methylation on A-5 on one strand, the other strand being methylated by the Eco57

COG id: COG1002

COG function: function code V; Type II restriction enzyme, methylase subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR011639 [H]

Pfam domain/function: PF07669 Eco57I [H]

EC number: =3.1.21.4; =2.1.1.72 [H]

Molecular weight: Translated: 74581; Mature: 74450

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSLTSDSQWEDIQSKDWFIEAQELAEEKSFFNWRLEYPDIFYDEAGEEKENPGFDVVL
CCCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEEEEE
GNPPYINAIELNDITTHEKDLWKKRFNSAKDAYDIYVLFLEQSLELSRTDGVVGLIVPNK
CCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCHHCCCCEEEEEECCC
HLSAPYAKTYREYIIDNHQMWKICDVSQLGVFEDPSVYPVIPFFRTERDFEGVDNIEIDK
CCCCCHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCCEECCHHCCCCCCCCCCCCEECC
PVSTVSISTGSEQMDVCAPSKLTKIGNNLWGPLLLDLEEQDAFWSTVEDTVQLDSEGTVQ
CCEEEEECCCCCCHHCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHEECCCCCEE
ASSTASEAEEFTVALSEEPPSKTNKKFIKTGGIDPFQSFWNSEEVRHQGDYYTKPVLDID
ECCCHHHHHHEEEEECCCCCCCCCCHHHHCCCCCHHHHHCCCHHHHHCCCCCCCCCCCCC
HPIITDLRRSQYNSEKLVFAKVASILEAFVDTDGEYASVDTNLFYDSNLDIRYYGAILNS
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCEEEEEEECCC
NVVLFLYSGMFGALRMRGGDFQFQAPQLKQVPVPSISIDTPDPERGSRVSTALDSYKAYL
CEEEEEECCHHHHHEECCCCCEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
EGSASRPKPEKDDVAHDFLAELTDRISELKQERESLNLALLDYLGIPTAGIPEDLEGKSL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCCCCCCCH
QELHMPAPGVADTLLSETGEDLDGLRIEGVSFSGDNSKLVMSVDVSYKPDDEDARETDRY
HHHCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHH
GRLAENEFETYDAMVFTGLSDKKRTLIEIFVPEAVSRAGGFADFRQSATKTISPLERLEN
CCHHCCHHHHHHEEEEECCCCCCCEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVLPDLDAIKNGLEKYEDVRQDANELDEKINKTDTLINEIVYSLYDLSTEEIDIIETSLE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
E
C
>Mature Secondary Structure 
AKSLTSDSQWEDIQSKDWFIEAQELAEEKSFFNWRLEYPDIFYDEAGEEKENPGFDVVL
CCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEEEEE
GNPPYINAIELNDITTHEKDLWKKRFNSAKDAYDIYVLFLEQSLELSRTDGVVGLIVPNK
CCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCHHCCCCEEEEEECCC
HLSAPYAKTYREYIIDNHQMWKICDVSQLGVFEDPSVYPVIPFFRTERDFEGVDNIEIDK
CCCCCHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCCEECCHHCCCCCCCCCCCCEECC
PVSTVSISTGSEQMDVCAPSKLTKIGNNLWGPLLLDLEEQDAFWSTVEDTVQLDSEGTVQ
CCEEEEECCCCCCHHCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHEECCCCCEE
ASSTASEAEEFTVALSEEPPSKTNKKFIKTGGIDPFQSFWNSEEVRHQGDYYTKPVLDID
ECCCHHHHHHEEEEECCCCCCCCCCHHHHCCCCCHHHHHCCCHHHHHCCCCCCCCCCCCC
HPIITDLRRSQYNSEKLVFAKVASILEAFVDTDGEYASVDTNLFYDSNLDIRYYGAILNS
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCEEEEEEECCC
NVVLFLYSGMFGALRMRGGDFQFQAPQLKQVPVPSISIDTPDPERGSRVSTALDSYKAYL
CEEEEEECCHHHHHEECCCCCEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
EGSASRPKPEKDDVAHDFLAELTDRISELKQERESLNLALLDYLGIPTAGIPEDLEGKSL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCCCCCCCH
QELHMPAPGVADTLLSETGEDLDGLRIEGVSFSGDNSKLVMSVDVSYKPDDEDARETDRY
HHHCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHH
GRLAENEFETYDAMVFTGLSDKKRTLIEIFVPEAVSRAGGFADFRQSATKTISPLERLEN
CCHHCCHHHHHHEEEEECCCCCCCEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVLPDLDAIKNGLEKYEDVRQDANELDEKINKTDTLINEIVYSLYDLSTEEIDIIETSLE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1334261; 1334260 [H]