Click here to switch to the map view.

The map label for this gene is tktB_1

Identifier: 15836426

GI number: 15836426

Start: 1023215

End: 1025212

Strand: Direct

Name: tktB_1

Synonym: CPj0893

Alternate gene names: 15836426

Gene position: 1023215-1025212 (Clockwise)

Preceding gene: 15836420

Following gene: 15836428

Centisome position: 83.42

GC content: 42.69

Gene sequence:

>1998_bases
ATGATCAATAAAGAATTAGATATTGGTATTTTAGGAAAAATTGCTGGGGCTATTAAACAAATTAGTATTGAATCCATCCA
AAAGGCCTCTTCTGGTCATCCAGGACTTCCCCTAGGATGCGCAGAACTTGCTGCCTATTTATATGGTTATGTCCTGCGGC
AAAATCCACGTGATCCCCATTGGATTAATAGGGATCGGTTTGTCTTGTCAGCAGGTCATGGATCTGCTCTTCTCTATTCT
TGTTTGCATCTTGCCGGATTTGATGTTTCCTTAGAGGATCTTCAGGAATTTCGCCAGCTTCACTCCCGAACTCCCGGGCA
TCCCGAGTACGGCGAAACTGTGGGAGTCGAAGCAACGACAGGTCCTCTGGGACAGGGATTAGGCAATGCTGTCGGCATGG
CGCTCTCTATGAAGATGTTGGAATCCCGATTCAATCGCCCAGGACATGAGATTTTTAACGGAAAAATCTATTGTTTGGCA
GGGGATGGCTGTTTTATGGAGGGAGTCAGCCACGAAGTTTGTAGCTTTGCAGGCTCTTTAAATTTAAATAATCTTGTGGT
CATCTATGACTACAATAATGTTGTTCTCGATGGATATCTTAATGAAATTAGTGTTGAGGATACAAAAAAACGTTTTGAAG
CCTATGGCTGGGATGTATATGAAATTGATGGGTATGATTTTACCCATATTCATGAGACATTCTCGAGCATCAAACGGGGG
CAGGAACGTCCTGTATTAGTGATTGCACATACAATTATTGGTCATGGTTCGCCTAAGGAAGGGACAAATAAGGCTCATGG
TTCTCCTTTAGGAGTCGAAGGGACTCATGAAACAAAACAGTTTTGGCATCTCCCTGAAGAAAAGTTTTTTGTCCCTCCTG
CAGTAAAGAACTTCTTTGCTCATAAAATACAAGAAGATCGAAAAGCACAGGAGCAATGGCTGGATGAAGTTCGTGTTTGG
TCAAAACAGTTCCCAGAATTACACGAAGAATTCGTTGCGTTGACCTCTCATAAGTTACCTAAAAACTTAGAATCCTTGGT
GCAGAGTGTAGAAATGCCAGACTCTATAGCTGGCCGGGCTGCTTCAAATAAACTGATCCAAGTATTAGTACAGCACATTC
CTTATTTGATTGGAGGGTCCGCAGATCTTTCAAGCTCAGATGGAACTTGGATTGCGAATGAGAAAGTCATCCATACGTAT
GACTTCTCTGGAAGGAACATTAAATACGGCGTTCGTGAGTTTGGTATGGCCACAATCATGAATGGTTTAGCTTATAGCCA
GGTATTTCGTCCTTTTGGTGGAACATTTTTAGTTTTTTCTGACTATATGCGTAATGCAATTCGCTTGGCCGCATTATCTA
AATTACCAGTCATCTATCAATTTACCCATGATTCTATATTTGTTGGAGAAGATGGACCTACGCATCAGCCTGTGGAACAA
TTGATGTCTTTGCGCGCGATCCCTGGATTGTATGTAATACGTCCTGCCGATGCTAATGAAGTTAGAGGAGCGTGGATTGC
AGGATTAAAGCACACAGGTCCTACAGTCATTGTCTTGTCGCGACAAGCATTGCCCACACTGCCTGCTGCGCATCGGCCTT
TTAAAGATGGTGTAGGTCGTGGTGCTTATATTGTCTTAAAAGAGTCAGGAGAAAAACCAGACTATACTCTCTTCGCTACA
GGGTCAGAAGTTTCTTTAGCTCTTTCTGTAGCTAAAGAACTCGAACACTTGGATAAGCAAGTGCGTGTAGTTTCTTTCCC
TTGTTGGGAGCTTTTTGAAGCTCAAGATGTGGACTACAAACAGAGTATTGTAGGCGGAGATCTTGGAATTCGTGTCTCTA
TAGAAGCAGGATCTGCTTTGGGGTGGTATAAGTATATCGGATCTGAAGGTTTAGCTATCGCTATGGATAGATTCGGATAC
TCAGGAGCTTCTGATGATGTATCAGAAGAATGTGGCTTTACTACAGAGCAAATCCTTCAGAGGATTCTCTCTCAATAG

Upstream 100 bases:

>100_bases
ATTTGTTTTTGAAAGAATTACAAGGTAAGAGTTCCTTGCTTTTTGCTTGGGGATTTCCTATAGTTGCTGCTTTTACATAG
AAGGTCTCCAGGGTTTACTT

Downstream 100 bases:

>100_bases
TCACTGTCGGAAGTTTCAGAGCCGCTAGCCATAGTGTCATCGGCTTCTCCAACTTCCATATGAGGTAATCCTCGATACTG
TTGATCCTTCTTATGGTCAG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MINKELDIGILGKIAGAIKQISIESIQKASSGHPGLPLGCAELAAYLYGYVLRQNPRDPHWINRDRFVLSAGHGSALLYS
CLHLAGFDVSLEDLQEFRQLHSRTPGHPEYGETVGVEATTGPLGQGLGNAVGMALSMKMLESRFNRPGHEIFNGKIYCLA
GDGCFMEGVSHEVCSFAGSLNLNNLVVIYDYNNVVLDGYLNEISVEDTKKRFEAYGWDVYEIDGYDFTHIHETFSSIKRG
QERPVLVIAHTIIGHGSPKEGTNKAHGSPLGVEGTHETKQFWHLPEEKFFVPPAVKNFFAHKIQEDRKAQEQWLDEVRVW
SKQFPELHEEFVALTSHKLPKNLESLVQSVEMPDSIAGRAASNKLIQVLVQHIPYLIGGSADLSSSDGTWIANEKVIHTY
DFSGRNIKYGVREFGMATIMNGLAYSQVFRPFGGTFLVFSDYMRNAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPVEQ
LMSLRAIPGLYVIRPADANEVRGAWIAGLKHTGPTVIVLSRQALPTLPAAHRPFKDGVGRGAYIVLKESGEKPDYTLFAT
GSEVSLALSVAKELEHLDKQVRVVSFPCWELFEAQDVDYKQSIVGGDLGIRVSIEAGSALGWYKYIGSEGLAIAMDRFGY
SGASDDVSEECGFTTEQILQRILSQ

Sequences:

>Translated_665_residues
MINKELDIGILGKIAGAIKQISIESIQKASSGHPGLPLGCAELAAYLYGYVLRQNPRDPHWINRDRFVLSAGHGSALLYS
CLHLAGFDVSLEDLQEFRQLHSRTPGHPEYGETVGVEATTGPLGQGLGNAVGMALSMKMLESRFNRPGHEIFNGKIYCLA
GDGCFMEGVSHEVCSFAGSLNLNNLVVIYDYNNVVLDGYLNEISVEDTKKRFEAYGWDVYEIDGYDFTHIHETFSSIKRG
QERPVLVIAHTIIGHGSPKEGTNKAHGSPLGVEGTHETKQFWHLPEEKFFVPPAVKNFFAHKIQEDRKAQEQWLDEVRVW
SKQFPELHEEFVALTSHKLPKNLESLVQSVEMPDSIAGRAASNKLIQVLVQHIPYLIGGSADLSSSDGTWIANEKVIHTY
DFSGRNIKYGVREFGMATIMNGLAYSQVFRPFGGTFLVFSDYMRNAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPVEQ
LMSLRAIPGLYVIRPADANEVRGAWIAGLKHTGPTVIVLSRQALPTLPAAHRPFKDGVGRGAYIVLKESGEKPDYTLFAT
GSEVSLALSVAKELEHLDKQVRVVSFPCWELFEAQDVDYKQSIVGGDLGIRVSIEAGSALGWYKYIGSEGLAIAMDRFGY
SGASDDVSEECGFTTEQILQRILSQ
>Mature_665_residues
MINKELDIGILGKIAGAIKQISIESIQKASSGHPGLPLGCAELAAYLYGYVLRQNPRDPHWINRDRFVLSAGHGSALLYS
CLHLAGFDVSLEDLQEFRQLHSRTPGHPEYGETVGVEATTGPLGQGLGNAVGMALSMKMLESRFNRPGHEIFNGKIYCLA
GDGCFMEGVSHEVCSFAGSLNLNNLVVIYDYNNVVLDGYLNEISVEDTKKRFEAYGWDVYEIDGYDFTHIHETFSSIKRG
QERPVLVIAHTIIGHGSPKEGTNKAHGSPLGVEGTHETKQFWHLPEEKFFVPPAVKNFFAHKIQEDRKAQEQWLDEVRVW
SKQFPELHEEFVALTSHKLPKNLESLVQSVEMPDSIAGRAASNKLIQVLVQHIPYLIGGSADLSSSDGTWIANEKVIHTY
DFSGRNIKYGVREFGMATIMNGLAYSQVFRPFGGTFLVFSDYMRNAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPVEQ
LMSLRAIPGLYVIRPADANEVRGAWIAGLKHTGPTVIVLSRQALPTLPAAHRPFKDGVGRGAYIVLKESGEKPDYTLFAT
GSEVSLALSVAKELEHLDKQVRVVSFPCWELFEAQDVDYKQSIVGGDLGIRVSIEAGSALGWYKYIGSEGLAIAMDRFGY
SGASDDVSEECGFTTEQILQRILSQ

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=578, Percent_Identity=28.0276816608997, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI4507521, Length=578, Percent_Identity=28.0276816608997, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI133778974, Length=579, Percent_Identity=25.3886010362694, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI225637459, Length=593, Percent_Identity=25.1264755480607, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI225637461, Length=561, Percent_Identity=24.9554367201426, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI225637463, Length=556, Percent_Identity=25, Blast_Score=119, Evalue=8e-27,
Organism=Escherichia coli, GI1788808, Length=658, Percent_Identity=45.7446808510638, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI48994911, Length=658, Percent_Identity=42.7051671732523, Blast_Score=536, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17539652, Length=561, Percent_Identity=27.4509803921569, Blast_Score=162, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6325331, Length=657, Percent_Identity=42.4657534246575, Blast_Score=493, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6319593, Length=658, Percent_Identity=41.1854103343465, Blast_Score=477, Evalue=1e-135,
Organism=Drosophila melanogaster, GI45551847, Length=583, Percent_Identity=27.1012006861063, Blast_Score=155, Evalue=8e-38,
Organism=Drosophila melanogaster, GI45550715, Length=583, Percent_Identity=27.1012006861063, Blast_Score=155, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24666278, Length=599, Percent_Identity=26.3772954924875, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24645119, Length=537, Percent_Identity=26.6294227188082, Blast_Score=139, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 73465; Mature: 73465

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKELDIGILGKIAGAIKQISIESIQKASSGHPGLPLGCAELAAYLYGYVLRQNPRDPH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
WINRDRFVLSAGHGSALLYSCLHLAGFDVSLEDLQEFRQLHSRTPGHPEYGETVGVEATT
CCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCEECC
GPLGQGLGNAVGMALSMKMLESRFNRPGHEIFNGKIYCLAGDGCFMEGVSHEVCSFAGSL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEEECCCHHHCCCCHHHHHHHCCC
NLNNLVVIYDYNNVVLDGYLNEISVEDTKKRFEAYGWDVYEIDGYDFTHIHETFSSIKRG
CCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC
QERPVLVIAHTIIGHGSPKEGTNKAHGSPLGVEGTHETKQFWHLPEEKFFVPPAVKNFFA
CCCCEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEECCHHHHHHHH
HKIQEDRKAQEQWLDEVRVWSKQFPELHEEFVALTSHKLPKNLESLVQSVEMPDSIAGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCHH
ASNKLIQVLVQHIPYLIGGSADLSSSDGTWIANEKVIHTYDFSGRNIKYGVREFGMATIM
HHHHHHHHHHHHCCEEECCCCCCCCCCCCEEECCCEEEEECCCCCCEECCHHHHHHHHHH
NGLAYSQVFRPFGGTFLVFSDYMRNAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPVEQ
HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCCCHHHHHH
LMSLRAIPGLYVIRPADANEVRGAWIAGLKHTGPTVIVLSRQALPTLPAAHRPFKDGVGR
HHHHHCCCCEEEEECCCCCCCCCHHEECCCCCCCEEEEEECCCCCCCCCCCCCCHHCCCC
GAYIVLKESGEKPDYTLFATGSEVSLALSVAKELEHLDKQVRVVSFPCWELFEAQDVDYK
CEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCCCCCHH
QSIVGGDLGIRVSIEAGSALGWYKYIGSEGLAIAMDRFGYSGASDDVSEECGFTTEQILQ
HHHCCCCCEEEEEEECCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCHHHCCCCHHHHHH
RILSQ
HHHCC
>Mature Secondary Structure
MINKELDIGILGKIAGAIKQISIESIQKASSGHPGLPLGCAELAAYLYGYVLRQNPRDPH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
WINRDRFVLSAGHGSALLYSCLHLAGFDVSLEDLQEFRQLHSRTPGHPEYGETVGVEATT
CCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCEECC
GPLGQGLGNAVGMALSMKMLESRFNRPGHEIFNGKIYCLAGDGCFMEGVSHEVCSFAGSL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEEECCCHHHCCCCHHHHHHHCCC
NLNNLVVIYDYNNVVLDGYLNEISVEDTKKRFEAYGWDVYEIDGYDFTHIHETFSSIKRG
CCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC
QERPVLVIAHTIIGHGSPKEGTNKAHGSPLGVEGTHETKQFWHLPEEKFFVPPAVKNFFA
CCCCEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEECCHHHHHHHH
HKIQEDRKAQEQWLDEVRVWSKQFPELHEEFVALTSHKLPKNLESLVQSVEMPDSIAGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCHH
ASNKLIQVLVQHIPYLIGGSADLSSSDGTWIANEKVIHTYDFSGRNIKYGVREFGMATIM
HHHHHHHHHHHHCCEEECCCCCCCCCCCCEEECCCEEEEECCCCCCEECCHHHHHHHHHH
NGLAYSQVFRPFGGTFLVFSDYMRNAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPVEQ
HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCCCHHHHHH
LMSLRAIPGLYVIRPADANEVRGAWIAGLKHTGPTVIVLSRQALPTLPAAHRPFKDGVGR
HHHHHCCCCEEEEECCCCCCCCCHHEECCCCCCCEEEEEECCCCCCCCCCCCCCHHCCCC
GAYIVLKESGEKPDYTLFATGSEVSLALSVAKELEHLDKQVRVVSFPCWELFEAQDVDYK
CEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCCCCCHH
QSIVGGDLGIRVSIEAGSALGWYKYIGSEGLAIAMDRFGYSGASDDVSEECGFTTEQILQ
HHHCCCCCEEEEEEECCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCHHHCCCCHHHHHH
RILSQ
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]