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The map label for this gene is pgmA

Identifier: 15836396

GI number: 15836396

Start: 980149

End: 980835

Strand: Reverse

Name: pgmA

Synonym: CPj0863

Alternate gene names: 15836396

Gene position: 980835-980149 (Counterclockwise)

Preceding gene: 15836399

Following gene: 15836395

Centisome position: 79.97

GC content: 39.59

Gene sequence:

>687_bases
ATGGCTCTTCTTATTTTATTACGTCATGGACAATCTGTATGGAATGAAAAAAATTTATTTTCTGGATGGGTAGACATTCC
TTTAAGCCAACAGGGAATTGAAGAGGCTTTTTCCGCAGGAAGAGCTATTCAAAATTTGCCTATAGACTGCATCTTTACCT
CTACCTTAGTACGTAGTCTGATGACCGCCTTACTCGCCATGACAAATCATCACTCTAAGAAGATCCCCTATATTGTTCAT
GAAGATCCCAAAGCAAAAGAGATGTCGAGGATCTACAGTGCGGAAGAAGAAAACAATATGATTCCTCTCTATCAATCTAG
TGCCCTCAACGAAAGAATGTACGGCGAACTTCAAGGAAAAAATAAAAAACAAACAGCCGAACAGTTCGGAGAAGAGCGGG
TCAAGCTGTGGAGGCGCAGCTACAAAACAGCTCCTCCTCAGGGAGAAAGCCTCTATGATACGAAACAAAGGACCTTGCCT
TACTTTGAAAAAAATATTTTGCCTCAACTGCAACATGGAAAAAACGTTTTTGTTTCTGCGCACGGAAATTCCTTACGCTC
TTTGATTATGGATCTAGAAAAATTAAGTGAGGAAGAGGTACTATCTTTAGAATTACCGACGGGAAAACCAGTTGTATATC
AATGGAAAAACCACAAAATCGAAAAGCACCCAGAATTTTTTGGTTAA

Upstream 100 bases:

>100_bases
TTCTTTGCTTAAAAACTTTTTTTACTTCTATATTTTCTACTAGACAAAAGTTGATTTCTGCTTATGCTTAGCTTCTCACC
CTAAATTCTAGTAGGAACAT

Downstream 100 bases:

>100_bases
ACAACCAAGTCGCTATTCCTCCTTCTGAGCGGGTTAAAGAAAGTTATGCCCTACACTCGGACATATTTTCTCTACCCCCC
GGCTCCGCGTTAAAATTAGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSLMTALLAMTNHHSKKIPYIVH
EDPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGKNKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLP
YFEKNILPQLQHGKNVFVSAHGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG

Sequences:

>Translated_228_residues
MALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSLMTALLAMTNHHSKKIPYIVH
EDPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGKNKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLP
YFEKNILPQLQHGKNVFVSAHGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG
>Mature_227_residues
ALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSLMTALLAMTNHHSKKIPYIVHE
DPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGKNKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLPY
FEKNILPQLQHGKNVFVSAHGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=257, Percent_Identity=35.0194552529183, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI4505753, Length=258, Percent_Identity=37.2093023255814, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI4502445, Length=242, Percent_Identity=35.1239669421488, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI40353764, Length=242, Percent_Identity=35.1239669421488, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI71274132, Length=258, Percent_Identity=35.2713178294574, Blast_Score=138, Evalue=4e-33,
Organism=Escherichia coli, GI1786970, Length=238, Percent_Identity=35.7142857142857, Blast_Score=155, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6322697, Length=254, Percent_Identity=35.0393700787402, Blast_Score=152, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6320183, Length=264, Percent_Identity=26.8939393939394, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324516, Length=263, Percent_Identity=25.8555133079848, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646216, Length=241, Percent_Identity=37.7593360995851, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI85725270, Length=243, Percent_Identity=36.2139917695473, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI85725272, Length=243, Percent_Identity=36.2139917695473, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24650981, Length=243, Percent_Identity=36.2139917695473, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571817, Length=242, Percent_Identity=28.5123966942149, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24648979, Length=242, Percent_Identity=28.5123966942149, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571815, Length=242, Percent_Identity=28.5123966942149, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 26269; Mature: 26138

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSL
CEEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHH
MTALLAMTNHHSKKIPYIVHEDPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGK
HHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCC
NKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLPYFEKNILPQLQHGKNVFVSA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHCCHHHCCCEEEEEE
HGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG
CCHHHHHHHHHHHHCCHHCEEEEECCCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
ALLILLRHGQSVWNEKNLFSGWVDIPLSQQGIEEAFSAGRAIQNLPIDCIFTSTLVRSL
EEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHH
MTALLAMTNHHSKKIPYIVHEDPKAKEMSRIYSAEEENNMIPLYQSSALNERMYGELQGK
HHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCC
NKKQTAEQFGEERVKLWRRSYKTAPPQGESLYDTKQRTLPYFEKNILPQLQHGKNVFVSA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHCCHHHCCCEEEEEE
HGNSLRSLIMDLEKLSEEEVLSLELPTGKPVVYQWKNHKIEKHPEFFG
CCHHHHHHHHHHHHCCHHCEEEEECCCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]