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The map label for this gene is nqrA

Identifier: 15836275

GI number: 15836275

Start: 838283

End: 839686

Strand: Direct

Name: nqrA

Synonym: CPj0743

Alternate gene names: 15836275

Gene position: 838283-839686 (Clockwise)

Preceding gene: 15836274

Following gene: 15836278

Centisome position: 68.34

GC content: 38.89

Gene sequence:

>1404_bases
ATGAAAATTACAGTCAATCGGGGTTTAGATTTATCCTTACAAGGGTCTCCCAAAGAATCTGGTTTCTATAACAAAATCGA
TCCAGAATTCGTATCTATAGACTTAAGGCCATTCCAACCTTTATCTCTTAAACTTAAGGTAGAGCAAGGAGATGCGGTCT
GTTCAGGAGCTCCTATAGCAGAATACAAGCACTTTCCTAACACCTACATTACCTCTCACGTTTCAGGAGTAGTTACCGCT
ATACGACGTGGAAATAAACGTTCTCTTTTAGATGTCATCATTAAGAAAACTCCTGGTCCTACATCTACAGAATATACGTA
TGATCTCCAAACTCTCTCACGTTCAGATCTTTCCGAAATCTTTAAGGAAAATGGGCTCTTTGCATTAATCAAACAACGTC
CTTTTGATATTCCCGCAATTCCAACACAAACTCCGAGAGATGTTTTCATCAATTTAGCTGACAATCGTCCTTTTACTCCA
AGCCCAGAAAAACATCTGGCTCTCTTTTCCTCTAGAGAAGAAGGATTTTATGTATTTGTGGTAGGAGTTCGAGCTATAGC
TAAACTTTTTGGACTCCGTCCTCATATAGTTTTCAGAGATCGTTTAACTCTACCTACGCAAGAACTAAAGACAATTGCTC
ACCTTCATACCGTTTCGGGACCATTCCCCTCTGGATCTCCATCGATACATATTCACAGCGTAGCCCCTATTACCAATGAG
AAAGAAGTGGTATTCACACTGTCATTTCAAGATGTCCTTACTATTGGCCATCTTTTCTTAAAGGGAAGAATTCTGCACGA
GCAAGTCACAGCACTTGCTGGTACTGCACTAAAAAGTTCTCTAAGACGCTATGTGATTACTACAAAAGGAGCTAGCTTCT
CTAGTTTAATCAATCTTAATGACATCTCGGATAACGATACATTAATTAGCGGAGATCCCTTAACAGGAAGGCTATGCAAA
AAGGAAGAGGAACCCTTTTTAGGATTTCGAGACCATTCAATTTCAGTCTTACACAACCCAACAAAACGGGAGTTGTTTAG
CTTTTTAAGAATTGGGTTTAACAAACCGACATTTACAAAAACCTATCTCTCAGGATTTTTCAAGAAAAAGCGTACCTATA
CGAATCCAGATACTAACCTCCACGGAGAAACTCGGCCGATTATTGATACTGACATCTATGATAAAGTTATGCCGATGAGA
ATTCCTGTAGTTCCTCTGATTAAAGCTGTAATTACTAAAAATTTTGATTTAGCTAATGAACTAGGGTTTTTAGAGGTTTG
TGGTGAAGATTTCGCCTTACCCACTCTTATAGATCCATCTAAAACAGAAATGCTTACCATAGTCAAGGAATCCTTAATAG
AGTATGCCAAGGAATCAGGGATCCTAACTCCCCATCAAGATTGA

Upstream 100 bases:

>100_bases
AATAAGAAAAAAAACTGGATTCCTCTATAAAATCACTTATAATCCCGATTGAATGAAACACCCAAGGACAGAGTCCAAGG
GACTTCCCTTTTAAATTTTT

Downstream 100 bases:

>100_bases
TTTTTTGTTCTTCAAAGAACTTAAAATTCAAATCCCTGATGCAGTAATTCCAAAATAAAAGGAGCGGAGTAACTAATAAT
CATATCTGCGCCAGCTCTCT

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKITVNRGLDLSLQGSPKESGFYNKIDPEFVSIDLRPFQPLSLKLKVEQGDAVCSGAPIAEYKHFPNTYITSHVSGVVTA
IRRGNKRSLLDVIIKKTPGPTSTEYTYDLQTLSRSDLSEIFKENGLFALIKQRPFDIPAIPTQTPRDVFINLADNRPFTP
SPEKHLALFSSREEGFYVFVVGVRAIAKLFGLRPHIVFRDRLTLPTQELKTIAHLHTVSGPFPSGSPSIHIHSVAPITNE
KEVVFTLSFQDVLTIGHLFLKGRILHEQVTALAGTALKSSLRRYVITTKGASFSSLINLNDISDNDTLISGDPLTGRLCK
KEEEPFLGFRDHSISVLHNPTKRELFSFLRIGFNKPTFTKTYLSGFFKKKRTYTNPDTNLHGETRPIIDTDIYDKVMPMR
IPVVPLIKAVITKNFDLANELGFLEVCGEDFALPTLIDPSKTEMLTIVKESLIEYAKESGILTPHQD

Sequences:

>Translated_467_residues
MKITVNRGLDLSLQGSPKESGFYNKIDPEFVSIDLRPFQPLSLKLKVEQGDAVCSGAPIAEYKHFPNTYITSHVSGVVTA
IRRGNKRSLLDVIIKKTPGPTSTEYTYDLQTLSRSDLSEIFKENGLFALIKQRPFDIPAIPTQTPRDVFINLADNRPFTP
SPEKHLALFSSREEGFYVFVVGVRAIAKLFGLRPHIVFRDRLTLPTQELKTIAHLHTVSGPFPSGSPSIHIHSVAPITNE
KEVVFTLSFQDVLTIGHLFLKGRILHEQVTALAGTALKSSLRRYVITTKGASFSSLINLNDISDNDTLISGDPLTGRLCK
KEEEPFLGFRDHSISVLHNPTKRELFSFLRIGFNKPTFTKTYLSGFFKKKRTYTNPDTNLHGETRPIIDTDIYDKVMPMR
IPVVPLIKAVITKNFDLANELGFLEVCGEDFALPTLIDPSKTEMLTIVKESLIEYAKESGILTPHQD
>Mature_467_residues
MKITVNRGLDLSLQGSPKESGFYNKIDPEFVSIDLRPFQPLSLKLKVEQGDAVCSGAPIAEYKHFPNTYITSHVSGVVTA
IRRGNKRSLLDVIIKKTPGPTSTEYTYDLQTLSRSDLSEIFKENGLFALIKQRPFDIPAIPTQTPRDVFINLADNRPFTP
SPEKHLALFSSREEGFYVFVVGVRAIAKLFGLRPHIVFRDRLTLPTQELKTIAHLHTVSGPFPSGSPSIHIHSVAPITNE
KEVVFTLSFQDVLTIGHLFLKGRILHEQVTALAGTALKSSLRRYVITTKGASFSSLINLNDISDNDTLISGDPLTGRLCK
KEEEPFLGFRDHSISVLHNPTKRELFSFLRIGFNKPTFTKTYLSGFFKKKRTYTNPDTNLHGETRPIIDTDIYDKVMPMR
IPVVPLIKAVITKNFDLANELGFLEVCGEDFALPTLIDPSKTEMLTIVKESLIEYAKESGILTPHQD

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_CHLPN (Q9Z7G2)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   D86583
- PIR:   E72040
- RefSeq:   NP_224939.1
- RefSeq:   NP_300799.1
- RefSeq:   NP_444555.1
- RefSeq:   NP_877043.1
- GeneID:   1467450
- GeneID:   895539
- GeneID:   919502
- GeneID:   963625
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0002
- KEGG:   cpn:CPn0743
- KEGG:   cpt:CpB0771
- TIGR:   CP_0002
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- BioCyc:   CPNE115711:CP_0002-MONOMER
- BioCyc:   CPNE115713:CPN0743-MONOMER
- BioCyc:   CPNE138677:CPJ0743-MONOMER
- BioCyc:   CPNE182082:CPB0771-MONOMER
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 52267; Mature: 52267

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITVNRGLDLSLQGSPKESGFYNKIDPEFVSIDLRPFQPLSLKLKVEQGDAVCSGAPIA
CEEEECCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEECCCCHH
EYKHFPNTYITSHVSGVVTAIRRGNKRSLLDVIIKKTPGPTSTEYTYDLQTLSRSDLSEI
HHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHCHHHHHHH
FKENGLFALIKQRPFDIPAIPTQTPRDVFINLADNRPFTPSPEKHLALFSSREEGFYVFV
HHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHEEEEECCCCCEEEEE
VGVRAIAKLFGLRPHIVFRDRLTLPTQELKTIAHLHTVSGPFPSGSPSIHIHSVAPITNE
EHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC
KEVVFTLSFQDVLTIGHLFLKGRILHEQVTALAGTALKSSLRRYVITTKGASFSSLINLN
CEEEEEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHEEEEC
DISDNDTLISGDPLTGRLCKKEEEPFLGFRDHSISVLHNPTKRELFSFLRIGFNKPTFTK
CCCCCCCEEECCCCCCHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHH
TYLSGFFKKKRTYTNPDTNLHGETRPIIDTDIYDKVMPMRIPVVPLIKAVITKNFDLANE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHH
LGFLEVCGEDFALPTLIDPSKTEMLTIVKESLIEYAKESGILTPHQD
CCHHEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKITVNRGLDLSLQGSPKESGFYNKIDPEFVSIDLRPFQPLSLKLKVEQGDAVCSGAPIA
CEEEECCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEECCCCHH
EYKHFPNTYITSHVSGVVTAIRRGNKRSLLDVIIKKTPGPTSTEYTYDLQTLSRSDLSEI
HHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHCHHHHHHH
FKENGLFALIKQRPFDIPAIPTQTPRDVFINLADNRPFTPSPEKHLALFSSREEGFYVFV
HHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHEEEEECCCCCEEEEE
VGVRAIAKLFGLRPHIVFRDRLTLPTQELKTIAHLHTVSGPFPSGSPSIHIHSVAPITNE
EHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC
KEVVFTLSFQDVLTIGHLFLKGRILHEQVTALAGTALKSSLRRYVITTKGASFSSLINLN
CEEEEEEEHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHEEEEC
DISDNDTLISGDPLTGRLCKKEEEPFLGFRDHSISVLHNPTKRELFSFLRIGFNKPTFTK
CCCCCCCEEECCCCCCHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHH
TYLSGFFKKKRTYTNPDTNLHGETRPIIDTDIYDKVMPMRIPVVPLIKAVITKNFDLANE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHH
LGFLEVCGEDFALPTLIDPSKTEMLTIVKESLIEYAKESGILTPHQD
CCHHEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362