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The map label for this gene is uhpC

Identifier: 15836197

GI number: 15836197

Start: 744322

End: 745689

Strand: Direct

Name: uhpC

Synonym: CPj0665

Alternate gene names: 15836197

Gene position: 744322-745689 (Clockwise)

Preceding gene: 15836191

Following gene: 15836198

Centisome position: 60.68

GC content: 42.18

Gene sequence:

>1368_bases
ATGAACGTTTGGACTAAATTTTTCCAACCTCCAAAGCACATTAAAGAAATTGAAGACCAAGAAGTGGTCAAGAAAAAATA
CAAATACTGGCGTATTCGTATTTTCTATAGCATGTTCATCGGCTACATTTTCTATTATTTCACAAGAAAAAGCTTTACCT
TTGCGATGCCCACGCTAATTGCTGATTTGGGTTTTGATAAAGCGCAATTAGGGATCATAGGAAGTACCTTATATTTTTCT
TATGGAATCAGTAAGTTTGTTAGCGGAGTCATGTCCGACCAATCCAATCCTAGATATTTCATGGCTATAGGATTGATGAT
TACAGGGCTCACTAACATCTTTTTCGGGATGTCATCCTCTATTGTATTATTTGCTCTTTGGTGGGGACTAAACGGATGGT
TCCAAGGGTGGGGCTGGCCTCCATGTGCTCGTCTACTCACCCACTGGTATGCGAAATCAGAACGGGGCACTTGGTGGAGT
GTGTGGAGTACCTCCCACAATATTGGGGGAGCACTTATTCCTATTCTCACAGGATTCATTATTGATTATAGTGGATGGCG
GGGAGCCATGTATGTTCCAGGCATTCTTTGTATTGGAATGGGTTTAGTTTTAATTAATCGTTTACGAGACACGCCTCAGT
CCTTAGGGCTACCTCCTATAGAGAAGTACAAGCGTGATCCCCATCACGCACATCACGAGGGCAAATCAGCCTCAGAAGGA
ACTGAGGAAATCGAACGCGAGCTATCCACTAGAGAAATTCTTTTTACCTATGTCCTTACAAATCAGTGGCTTTGGTTTTT
AGCTGCTGCCTCGTTCTTTATTTATATAGTACGAATGGCAGTCAACGATTGGAGCGCTTTATTCCTTATTGAGACAAAAC
ATTATGCGGCAGTGAAAGCCAATTTTTGCGTATCTCTATTTGAGATTGGTGGTTTATTCGGCATGCTAGTTGCTGGTTGG
TTATCTGATAAGATTTCTAAGGGCAATCGTGGGCCTATGAACGTCCTCTTCTCTTTAGGTTTGCTGTTTGCTATTTTAGG
CATGTGGTTTTCACGTAGTCATAATCAGTGGTGGGTGGACGGAACCTTACTTTTCGTTATTGGTTTTTTCTTATACGGCC
CTCAAATGATGATCGGTCTAGCAGCAGCAGAACTCTCTCATAAAAAAGCTGCTGGTACTGCTAGCGGATTTACTGGATGG
TTCGCTTATTTTGGAGCTACCTTTGCAGGGTATCCTTTAGGAAAGGTTACTGATGTTTGGGGGTGGAAAGGGTTTTTCAT
TGCTCTCTTAGCCTGTGCATCCATAGCTTTATTGCTCTTTTTACCAACTTGGAACGCTACGGAGAAAAACACTCGTAGTA
AAGCCTAG

Upstream 100 bases:

>100_bases
AAACGATTCCCTCCTTGTTTTTTCATCCTTGATATGGTAAAGTAGGCTTTTCTTCGCATTTCATCTCAGTGAAAAAGATT
TTACACATGGAAATTGAAAG

Downstream 100 bases:

>100_bases
CCGTTCTTGAGGATTTTTTTTGACCTGGATACCCCTTCACTGTCATTCTCAATACTCTGTTCTTGATGCAATGAGCTCCA
TCAAAGATTTCGTTGCGAAA

Product: hexosphosphate transport

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNVWTKFFQPPKHIKEIEDQEVVKKKYKYWRIRIFYSMFIGYIFYYFTRKSFTFAMPTLIADLGFDKAQLGIIGSTLYFS
YGISKFVSGVMSDQSNPRYFMAIGLMITGLTNIFFGMSSSIVLFALWWGLNGWFQGWGWPPCARLLTHWYAKSERGTWWS
VWSTSHNIGGALIPILTGFIIDYSGWRGAMYVPGILCIGMGLVLINRLRDTPQSLGLPPIEKYKRDPHHAHHEGKSASEG
TEEIERELSTREILFTYVLTNQWLWFLAAASFFIYIVRMAVNDWSALFLIETKHYAAVKANFCVSLFEIGGLFGMLVAGW
LSDKISKGNRGPMNVLFSLGLLFAILGMWFSRSHNQWWVDGTLLFVIGFFLYGPQMMIGLAAAELSHKKAAGTASGFTGW
FAYFGATFAGYPLGKVTDVWGWKGFFIALLACASIALLLFLPTWNATEKNTRSKA

Sequences:

>Translated_455_residues
MNVWTKFFQPPKHIKEIEDQEVVKKKYKYWRIRIFYSMFIGYIFYYFTRKSFTFAMPTLIADLGFDKAQLGIIGSTLYFS
YGISKFVSGVMSDQSNPRYFMAIGLMITGLTNIFFGMSSSIVLFALWWGLNGWFQGWGWPPCARLLTHWYAKSERGTWWS
VWSTSHNIGGALIPILTGFIIDYSGWRGAMYVPGILCIGMGLVLINRLRDTPQSLGLPPIEKYKRDPHHAHHEGKSASEG
TEEIERELSTREILFTYVLTNQWLWFLAAASFFIYIVRMAVNDWSALFLIETKHYAAVKANFCVSLFEIGGLFGMLVAGW
LSDKISKGNRGPMNVLFSLGLLFAILGMWFSRSHNQWWVDGTLLFVIGFFLYGPQMMIGLAAAELSHKKAAGTASGFTGW
FAYFGATFAGYPLGKVTDVWGWKGFFIALLACASIALLLFLPTWNATEKNTRSKA
>Mature_455_residues
MNVWTKFFQPPKHIKEIEDQEVVKKKYKYWRIRIFYSMFIGYIFYYFTRKSFTFAMPTLIADLGFDKAQLGIIGSTLYFS
YGISKFVSGVMSDQSNPRYFMAIGLMITGLTNIFFGMSSSIVLFALWWGLNGWFQGWGWPPCARLLTHWYAKSERGTWWS
VWSTSHNIGGALIPILTGFIIDYSGWRGAMYVPGILCIGMGLVLINRLRDTPQSLGLPPIEKYKRDPHHAHHEGKSASEG
TEEIERELSTREILFTYVLTNQWLWFLAAASFFIYIVRMAVNDWSALFLIETKHYAAVKANFCVSLFEIGGLFGMLVAGW
LSDKISKGNRGPMNVLFSLGLLFAILGMWFSRSHNQWWVDGTLLFVIGFFLYGPQMMIGLAAAELSHKKAAGTASGFTGW
FAYFGATFAGYPLGKVTDVWGWKGFFIALLACASIALLLFLPTWNATEKNTRSKA

Specific function: Transport protein for sugar phosphate uptake

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family

Homologues:

Organism=Homo sapiens, GI256219598, Length=448, Percent_Identity=34.8214285714286, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI4503847, Length=448, Percent_Identity=34.8214285714286, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI256219483, Length=448, Percent_Identity=34.8214285714286, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI256219543, Length=470, Percent_Identity=33.1914893617021, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI256219564, Length=374, Percent_Identity=31.8181818181818, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI46361976, Length=391, Percent_Identity=25.3196930946292, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI49619231, Length=416, Percent_Identity=23.7980769230769, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI223717983, Length=403, Percent_Identity=24.0694789081886, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI38093649, Length=403, Percent_Identity=24.0694789081886, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI14150047, Length=189, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87082310, Length=440, Percent_Identity=46.1363636363636, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1788573, Length=443, Percent_Identity=40.1805869074492, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI2367259, Length=450, Percent_Identity=31.1111111111111, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1789152, Length=430, Percent_Identity=20, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI2367379, Length=184, Percent_Identity=23.3695652173913, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17542316, Length=469, Percent_Identity=21.5351812366738, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17561094, Length=442, Percent_Identity=22.8506787330317, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133930953, Length=456, Percent_Identity=21.2719298245614, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI133901854, Length=469, Percent_Identity=20.8955223880597, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133901856, Length=469, Percent_Identity=20.8955223880597, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17539138, Length=298, Percent_Identity=24.1610738255034, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=453, Percent_Identity=20.9713024282561, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=390, Percent_Identity=21.2820512820513, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24656861, Length=482, Percent_Identity=24.2738589211618, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24656866, Length=498, Percent_Identity=23.6947791164659, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45550478, Length=498, Percent_Identity=23.6947791164659, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UHPT_CHLPN (Q9Z7N9)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   A72050
- PIR:   F86573
- RefSeq:   NP_224861.1
- RefSeq:   NP_300721.1
- RefSeq:   NP_444634.1
- RefSeq:   NP_876963.1
- ProteinModelPortal:   Q9Z7N9
- GeneID:   1467370
- GeneID:   895238
- GeneID:   919371
- GeneID:   963768
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0082
- KEGG:   cpn:CPn0665
- KEGG:   cpt:CpB0691
- TIGR:   CP_0082
- HOGENOM:   HBG559184
- OMA:   RKHEETT
- PhylomeDB:   Q9Z7N9
- ProtClustDB:   CLSK871435
- BioCyc:   CPNE115711:CP_0082-MONOMER
- BioCyc:   CPNE115713:CPN0665-MONOMER
- BioCyc:   CPNE138677:CPJ0665-MONOMER
- BioCyc:   CPNE182082:CPB0691-MONOMER
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159
- TIGRFAMs:   TIGR00881

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 51660; Mature: 51660

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00942 GLPT; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb8dcf50)-; HASH(0xd31c3a4)-; HASH(0xc943e74)-; HASH(0xb5f7474)-; HASH(0xcec79fc)-; HASH(0xd1ac6e4)-; HASH(0xcf83168)-; HASH(0xcc5760c)-; HASH(0xd1bbaf0)-; HASH(0xca44df8)-; HASH(0xcfcadd8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362