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The map label for this gene is lplA_2

Identifier: 15836150

GI number: 15836150

Start: 711627

End: 712334

Strand: Direct

Name: lplA_2

Synonym: CPj0618

Alternate gene names: 15836150

Gene position: 711627-712334 (Clockwise)

Preceding gene: 15836149

Following gene: 15836188

Centisome position: 58.02

GC content: 39.97

Gene sequence:

>708_bases
ATGCCCACCACTAACTGTATTTTCCTAGATTTACGGGGACACTCTATTCTTCACCAACTGCAAATTGAAGAGGCTTTACT
AAGAGTCGCGAATCAAAATTTTTGCATTATAAATTCAGGTGCCAAAGACTCTATAGTTTTAGGAATTTCTCGAAACTTGA
ATCAAGACGTTCATATTTCTAGAGCACAAGCAGACCATATTCCTATCATACGCCGCTATAGTGGAGGGGGGACGGTATTC
ATAGATTCCAATACCTTGATGGTATCTTGGATTATGAACAGTTCAGAAGCTTCTGCCCAACCTCAGGAATTATTAGCATG
GACTTATGGCATCTATAGTCCACTACTTCCTAATACCTTTTCTATTCGAGAAAACGACTATGTTCTTGGTCATAAGAAAA
TAGGAGGTAATGCACAATATATTCAAAGACATCGCTGGGTACATCACACGACATTTCTGTGGGATATCGACCTAGATAAG
TTGTCCTACTACCTGCCAATTCCTCAACAACAACCTACCTACCGTAATCAACGCTCTCACGAAGAATTTTTGACTACGTT
ACGTCCTTGGTTCCCCTCTCGCGATGACTTCTTGGAAAGGATCAAGGCATCTGGTAGTTTGTTGTTTACCTGGGAAGAAT
TTCTTGATAATGAGCTAGAAGAAATTCTTGCTCAACCTCATCGTAAAGCAACTACAGTACTAAACTAA

Upstream 100 bases:

>100_bases
AAATTAGCGAAATTTACACCTCGAACTCTTGGTTCTGCATCGAGAATATCGGGCATAGCTTCTGCTGACATTCAAGTTTT
GATGATAGCTTTAAAAAAAC

Downstream 100 bases:

>100_bases
ACGAGAGGTTTCGAAGCGTTAACAACTTCTATCTTACTGAAGAAGTAAGCGATTTCGACAGCAGCATTTTCTAAAGTATC
AGATCCATGAACAGCATTCA

Product: lipoate-protein ligase A

Products: NA

Alternate protein names: Lipoate--protein ligase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPTTNCIFLDLRGHSILHQLQIEEALLRVANQNFCIINSGAKDSIVLGISRNLNQDVHISRAQADHIPIIRRYSGGGTVF
IDSNTLMVSWIMNSSEASAQPQELLAWTYGIYSPLLPNTFSIRENDYVLGHKKIGGNAQYIQRHRWVHHTTFLWDIDLDK
LSYYLPIPQQQPTYRNQRSHEEFLTTLRPWFPSRDDFLERIKASGSLLFTWEEFLDNELEEILAQPHRKATTVLN

Sequences:

>Translated_235_residues
MPTTNCIFLDLRGHSILHQLQIEEALLRVANQNFCIINSGAKDSIVLGISRNLNQDVHISRAQADHIPIIRRYSGGGTVF
IDSNTLMVSWIMNSSEASAQPQELLAWTYGIYSPLLPNTFSIRENDYVLGHKKIGGNAQYIQRHRWVHHTTFLWDIDLDK
LSYYLPIPQQQPTYRNQRSHEEFLTTLRPWFPSRDDFLERIKASGSLLFTWEEFLDNELEEILAQPHRKATTVLN
>Mature_234_residues
PTTNCIFLDLRGHSILHQLQIEEALLRVANQNFCIINSGAKDSIVLGISRNLNQDVHISRAQADHIPIIRRYSGGGTVFI
DSNTLMVSWIMNSSEASAQPQELLAWTYGIYSPLLPNTFSIRENDYVLGHKKIGGNAQYIQRHRWVHHTTFLWDIDLDKL
SYYLPIPQQQPTYRNQRSHEEFLTTLRPWFPSRDDFLERIKASGSLLFTWEEFLDNELEEILAQPHRKATTVLN

Specific function: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes [H]

COG id: COG0095

COG function: function code H; Lipoate-protein ligase A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lplA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR005107
- InterPro:   IPR019491
- InterPro:   IPR004562 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF10437 Lip_prot_lig_C [H]

EC number: =2.7.7.63 [H]

Molecular weight: Translated: 27203; Mature: 27072

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTNCIFLDLRGHSILHQLQIEEALLRVANQNFCIINSGAKDSIVLGISRNLNQDVHIS
CCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCEEEE
RAQADHIPIIRRYSGGGTVFIDSNTLMVSWIMNSSEASAQPQELLAWTYGIYSPLLPNTF
CCCCCCCCEEEEECCCCEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEE
SIRENDYVLGHKKIGGNAQYIQRHRWVHHTTFLWDIDLDKLSYYLPIPQQQPTYRNQRSH
EECCCCEEEEEEECCCCHHHHHHHCCEEEEEEEEEEEHHHEEEEECCCCCCCCCCCCCHH
EEFLTTLRPWFPSRDDFLERIKASGSLLFTWEEFLDNELEEILAQPHRKATTVLN
HHHHHHHCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure 
PTTNCIFLDLRGHSILHQLQIEEALLRVANQNFCIINSGAKDSIVLGISRNLNQDVHIS
CCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCEEEE
RAQADHIPIIRRYSGGGTVFIDSNTLMVSWIMNSSEASAQPQELLAWTYGIYSPLLPNTF
CCCCCCCCEEEEECCCCEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEE
SIRENDYVLGHKKIGGNAQYIQRHRWVHHTTFLWDIDLDKLSYYLPIPQQQPTYRNQRSH
EECCCCEEEEEEECCCCHHHHHHHCCEEEEEEEEEEEHHHEEEEECCCCCCCCCCCCCHH
EEFLTTLRPWFPSRDDFLERIKASGSLLFTWEEFLDNELEEILAQPHRKATTVLN
HHHHHHHCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]