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The map label for this gene is coaE

Identifier: 15836143

GI number: 15836143

Start: 700738

End: 701346

Strand: Reverse

Name: coaE

Synonym: CPj0611

Alternate gene names: 15836143

Gene position: 701346-700738 (Counterclockwise)

Preceding gene: 15836144

Following gene: 15836142

Centisome position: 57.18

GC content: 37.6

Gene sequence:

>609_bases
ATGTTAAAATTATTAAAAGTTTCCATTACAGGGGATCTCTCTTCTGGGAAGACTGAAGCTTGCCAAGTTTTTCAGGAATT
GGGAGCCTATGTAGTTAGTGCTGATGAAATTTCGAATAGTTTCCTTATCCCTCATACACGCATAGGTCGTCGTGTTATAG
ATCTTTTAGGATCGGATGTTGTAGTTGATGGGGCGTATGATGCGCAAGCCATAGCAGCCAAAGTTTTTTACAATTCCGTT
CTATTACAAGGTCTGGAAGCCATTCTACATCCAGAAGTTTGTCGAATTATTGAGGAACAATATCATCAAAGTATTCAAGA
TGGGAACTATCCGTTATTTGTCGCAGAAGTGCCTTTATTATACGAAATACACTATGCTAAGTGGTTTGATTCAGTGATCC
TTGTTATGGCAAACGAAGATATTCGACGCGAGAGATTCATGAAGAAAACAGGGCGTTCCTCTGAAGACTTTGATCAAAGG
TGTTCGCGTTTTCTAAATGTCGAAGAAAAGTTAGCACAAGCAGATGTTGTTGTTGAAAACAACGGAACTAAAAAAGAATT
ACATCAAAAAATTGAAGAATATTTTTACGCTTTAAAGGGAGCATTATGA

Upstream 100 bases:

>100_bases
TAGAAGAGATGCAAAGACTAGTGAGAGAGAAGATGGAATCAGCTATGACTTTATCCGTTCCTATAGTTGTGAATATCTTA
ATTGGAAAAAATTGGGCAGA

Downstream 100 bases:

>100_bases
AAGAAGAGCGTTCTTCAGAAATCTTGCCTAGGGTGAAGGAAACGAAAAAACATGCTTACGTTTCTATGCAGGAAAAATCT
TGTGTAGGGGAGTGTGCTGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MLKLLKVSITGDLSSGKTEACQVFQELGAYVVSADEISNSFLIPHTRIGRRVIDLLGSDVVVDGAYDAQAIAAKVFYNSV
LLQGLEAILHPEVCRIIEEQYHQSIQDGNYPLFVAEVPLLYEIHYAKWFDSVILVMANEDIRRERFMKKTGRSSEDFDQR
CSRFLNVEEKLAQADVVVENNGTKKELHQKIEEYFYALKGAL

Sequences:

>Translated_202_residues
MLKLLKVSITGDLSSGKTEACQVFQELGAYVVSADEISNSFLIPHTRIGRRVIDLLGSDVVVDGAYDAQAIAAKVFYNSV
LLQGLEAILHPEVCRIIEEQYHQSIQDGNYPLFVAEVPLLYEIHYAKWFDSVILVMANEDIRRERFMKKTGRSSEDFDQR
CSRFLNVEEKLAQADVVVENNGTKKELHQKIEEYFYALKGAL
>Mature_202_residues
MLKLLKVSITGDLSSGKTEACQVFQELGAYVVSADEISNSFLIPHTRIGRRVIDLLGSDVVVDGAYDAQAIAAKVFYNSV
LLQGLEAILHPEVCRIIEEQYHQSIQDGNYPLFVAEVPLLYEIHYAKWFDSVILVMANEDIRRERFMKKTGRSSEDFDQR
CSRFLNVEEKLAQADVVVENNGTKKELHQKIEEYFYALKGAL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=196, Percent_Identity=26.530612244898, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI191252795, Length=196, Percent_Identity=26.530612244898, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786292, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554944, Length=194, Percent_Identity=25.7731958762887, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320402, Length=195, Percent_Identity=25.1282051282051, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644728, Length=182, Percent_Identity=24.7252747252747, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22906; Mature: 22906

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLLKVSITGDLSSGKTEACQVFQELGAYVVSADEISNSFLIPHTRIGRRVIDLLGSDV
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHEEEHHHCCCCCCCCHHHHHHHHHHHHCCCE
VVDGAYDAQAIAAKVFYNSVLLQGLEAILHPEVCRIIEEQYHQSIQDGNYPLFVAEVPLL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
YEIHYAKWFDSVILVMANEDIRRERFMKKTGRSSEDFDQRCSRFLNVEEKLAQADVVVEN
HHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHCEEEEC
NGTKKELHQKIEEYFYALKGAL
CCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKLLKVSITGDLSSGKTEACQVFQELGAYVVSADEISNSFLIPHTRIGRRVIDLLGSDV
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHEEEHHHCCCCCCCCHHHHHHHHHHHHCCCE
VVDGAYDAQAIAAKVFYNSVLLQGLEAILHPEVCRIIEEQYHQSIQDGNYPLFVAEVPLL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
YEIHYAKWFDSVILVMANEDIRRERFMKKTGRSSEDFDQRCSRFLNVEEKLAQADVVVEN
HHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHCEEEEC
NGTKKELHQKIEEYFYALKGAL
CCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]